Guide for the Care and
Guide
Use
forofthe
Laboratory
Care and
Guide
Animals,
Use
forofthe
Laboratory
8th
Care
edition.pdf
andAnimals,
Use of Laboratory
8th edition.pdf
Animals, 8th edition.pdf
GUIDE
FOR THE CARE AND USE OF
LABORATORY
ANIMALS
Eighth Edition
Committee for the Update of the Guide for the Care
and Use of Laboratory Animals
Institute for Laboratory Animal Research
Division on Earth and Life Studies
Guide for the Care and
Guide
Use
forofthe
Laboratory
Care and
Guide
Animals,
Use
forofthe
Laboratory
8th
Care
edition.pdf
andAnimals,
Use of Laboratory
8th edition.pdf
Animals, 8th edition.pdf
,Guide for the Care and
Guide
Use
forofthe
Laboratory
Care and
Guide
Animals,
Use
forofthe
Laboratory
8th
Care
edition.pdf
andAnimals,
Use of Laboratory
8th edition.pdf
Animals, 8th edition.pdf
THE NATIONAL ACADEMIES PRESS 500 Fifth Street, NW Washington, DC 20001
NOTICE: The project that is the subject of this report was approved by the Govern-
ing Board of the National Research Council, whose members are drawn from the
councils of the National Academy of Sciences, the National Academy of Engineer-
ing, and the Institute of Medicine. The members of the Committee responsible for
the report were chosen for their special competences and with regard for appropriate
balance.
This study was supported by the Office of Extramural Research, Office of the Direc-
tor, National Institutes of Health/Department of Health and Human Services under
Contract Number N01-OD-4-2139 Task Order #188; the Office of Research Integrity,
Department of Health and Human Services; the Animal and Plant Health Inspection
Service, U.S. Department of Agriculture; Association for Assessment and Accreditation
of Laboratory Animal Care International; American Association for Laboratory Animal
Science; Abbott Fund; Pfizer; American College of Laboratory Animal Medicine; Ameri-
can Society of Laboratory Animal Practitioners; Association of Primate Veternarians.
Any opinions, findings, conclusions, or recommendations expressed in this pub-
lication are those of the authors and do not necessarily reflect the views of the
organizations or agencies that provided support for the project. The content of
this publication does not necessarily reflect the views or policies of the National
Institutes of Health, nor does mention of trade names, commercial products, or
organizations imply endorsement by the US government.
International Standard Book Number-13: 978-0-309-15400-0 (Book)
International Standard Book Number-10: 0-309-15400-6 (Book)
International Standard Book Number-13: 978-0-309-15401-7 (PDF)
International Standard Book Number-10: 0-309-15401-4 (PDF)
Library of Congress Control Number: 2010940400
Additional copies of this report are available from the National Academies Press,
500 Fifth Street, NW, Lockbox 285, Washington, DC 20055; (800) 624-6242 or
(202) 334-3313 (in the Washington metropolitan area); http://www.nap.edu.
Copyright 2011 by the National Academy of Sciences. All rights reserved.
Printed in the United States of America.
Guide for the Care and
Guide
Use
forofthe
Laboratory
Care and
Guide
Animals,
Use
forofthe
Laboratory
8th
Care
edition.pdf
andAnimals,
Use of Laboratory
8th edition.pdf
Animals, 8th edition.pdf
,Guide for the Care and
Guide
Use
forofthe
Laboratory
Care and
Guide
Animals,
Use
forofthe
Laboratory
8th
Care
edition.pdf
andAnimals,
Use of Laboratory
8th edition.pdf
Animals, 8th edition.pdf
The National Academy of Sciences is a private, nonprofit, self-perpetuating society
of distinguished scholars engaged in scientific and engineering research, dedicated
to the furtherance of science and technology and to their use for the general welfare.
Upon the authority of the charter granted to it by the Congress in 1863, the Acad-
emy has a mandate that requires it to advise the federal government on scientific
and technical matters. Dr. Ralph J. Cicerone is president of the National Academy
of Sciences.
The National Academy of Engineering was established in 1964, under the charter
of the National Academy of Sciences, as a parallel organization of outstanding
engineers. It is autonomous in its administration and in the selection of its members,
sharing with the National Academy of Sciences the responsibility for advising the
federal government. The National Academy of Engineering also sponsors engineer-
ing programs aimed at meeting national needs, encourages education and research,
and recognizes the superior achievements of engineers. Dr. Charles Vest is president
of the National Academy of Engineering.
The Institute of Medicine was established in 1970 by the National Academy of
Sciences to secure the services of eminent members of appropriate professions in
the examination of policy matters pertaining to the health of the public. The Insti-
tute acts under the responsibility given to the National Academy of Sciences by its
congressional charter to be an adviser to the federal government and, upon its own
initiative, to identify issues of medical care, research, and education. Dr. Harvey V.
Fineberg is president of the Institute of Medicine.
The National Research Council was organized by the National Academy of Sci-
ences in 1916 to associate the broad community of science and technology with the
Academy’s purposes of furthering knowledge and advising the federal government.
Functioning in accordance with general policies determined by the Academy, the
Council has become the principal operating agency of both the National Academy
of Sciences and the National Academy of Engineering in providing services to
the government, the public, and the scientific and engineering communities. The
Council is administered jointly by both Academies and the Institute of Medicine.
Dr. Ralph J. Cicerone and Dr. Charles M. Vest are chair and vice chair, respectively,
of the National Research Council.
www.national-academies.org
Guide for the Care and
Guide
Use
forofthe
Laboratory
Care and
Guide
Animals,
Use
forofthe
Laboratory
8th
Care
edition.pdf
andAnimals,
Use of Laboratory
8th edition.pdf
Animals, 8th edition.pdf
, Guide for the Care and
Guide
Use
forofthe
Laboratory
Care and
Guide
Animals,
Use
forofthe
Laboratory
8th
Care
edition.pdf
andAnimals,
Use of Laboratory
8th edition.pdf
Animals, 8th edition.pdf
Guide for the Care and
Guide
Use
forofthe
Laboratory
Care and
Guide
Animals,
Use
forofthe
Laboratory
8th
Care
edition.pdf
andAnimals,
Use of Laboratory
8th edition.pdf
Animals, 8th edition.pdf
Guide
Use
forofthe
Laboratory
Care and
Guide
Animals,
Use
forofthe
Laboratory
8th
Care
edition.pdf
andAnimals,
Use of Laboratory
8th edition.pdf
Animals, 8th edition.pdf
GUIDE
FOR THE CARE AND USE OF
LABORATORY
ANIMALS
Eighth Edition
Committee for the Update of the Guide for the Care
and Use of Laboratory Animals
Institute for Laboratory Animal Research
Division on Earth and Life Studies
Guide for the Care and
Guide
Use
forofthe
Laboratory
Care and
Guide
Animals,
Use
forofthe
Laboratory
8th
Care
edition.pdf
andAnimals,
Use of Laboratory
8th edition.pdf
Animals, 8th edition.pdf
,Guide for the Care and
Guide
Use
forofthe
Laboratory
Care and
Guide
Animals,
Use
forofthe
Laboratory
8th
Care
edition.pdf
andAnimals,
Use of Laboratory
8th edition.pdf
Animals, 8th edition.pdf
THE NATIONAL ACADEMIES PRESS 500 Fifth Street, NW Washington, DC 20001
NOTICE: The project that is the subject of this report was approved by the Govern-
ing Board of the National Research Council, whose members are drawn from the
councils of the National Academy of Sciences, the National Academy of Engineer-
ing, and the Institute of Medicine. The members of the Committee responsible for
the report were chosen for their special competences and with regard for appropriate
balance.
This study was supported by the Office of Extramural Research, Office of the Direc-
tor, National Institutes of Health/Department of Health and Human Services under
Contract Number N01-OD-4-2139 Task Order #188; the Office of Research Integrity,
Department of Health and Human Services; the Animal and Plant Health Inspection
Service, U.S. Department of Agriculture; Association for Assessment and Accreditation
of Laboratory Animal Care International; American Association for Laboratory Animal
Science; Abbott Fund; Pfizer; American College of Laboratory Animal Medicine; Ameri-
can Society of Laboratory Animal Practitioners; Association of Primate Veternarians.
Any opinions, findings, conclusions, or recommendations expressed in this pub-
lication are those of the authors and do not necessarily reflect the views of the
organizations or agencies that provided support for the project. The content of
this publication does not necessarily reflect the views or policies of the National
Institutes of Health, nor does mention of trade names, commercial products, or
organizations imply endorsement by the US government.
International Standard Book Number-13: 978-0-309-15400-0 (Book)
International Standard Book Number-10: 0-309-15400-6 (Book)
International Standard Book Number-13: 978-0-309-15401-7 (PDF)
International Standard Book Number-10: 0-309-15401-4 (PDF)
Library of Congress Control Number: 2010940400
Additional copies of this report are available from the National Academies Press,
500 Fifth Street, NW, Lockbox 285, Washington, DC 20055; (800) 624-6242 or
(202) 334-3313 (in the Washington metropolitan area); http://www.nap.edu.
Copyright 2011 by the National Academy of Sciences. All rights reserved.
Printed in the United States of America.
Guide for the Care and
Guide
Use
forofthe
Laboratory
Care and
Guide
Animals,
Use
forofthe
Laboratory
8th
Care
edition.pdf
andAnimals,
Use of Laboratory
8th edition.pdf
Animals, 8th edition.pdf
,Guide for the Care and
Guide
Use
forofthe
Laboratory
Care and
Guide
Animals,
Use
forofthe
Laboratory
8th
Care
edition.pdf
andAnimals,
Use of Laboratory
8th edition.pdf
Animals, 8th edition.pdf
The National Academy of Sciences is a private, nonprofit, self-perpetuating society
of distinguished scholars engaged in scientific and engineering research, dedicated
to the furtherance of science and technology and to their use for the general welfare.
Upon the authority of the charter granted to it by the Congress in 1863, the Acad-
emy has a mandate that requires it to advise the federal government on scientific
and technical matters. Dr. Ralph J. Cicerone is president of the National Academy
of Sciences.
The National Academy of Engineering was established in 1964, under the charter
of the National Academy of Sciences, as a parallel organization of outstanding
engineers. It is autonomous in its administration and in the selection of its members,
sharing with the National Academy of Sciences the responsibility for advising the
federal government. The National Academy of Engineering also sponsors engineer-
ing programs aimed at meeting national needs, encourages education and research,
and recognizes the superior achievements of engineers. Dr. Charles Vest is president
of the National Academy of Engineering.
The Institute of Medicine was established in 1970 by the National Academy of
Sciences to secure the services of eminent members of appropriate professions in
the examination of policy matters pertaining to the health of the public. The Insti-
tute acts under the responsibility given to the National Academy of Sciences by its
congressional charter to be an adviser to the federal government and, upon its own
initiative, to identify issues of medical care, research, and education. Dr. Harvey V.
Fineberg is president of the Institute of Medicine.
The National Research Council was organized by the National Academy of Sci-
ences in 1916 to associate the broad community of science and technology with the
Academy’s purposes of furthering knowledge and advising the federal government.
Functioning in accordance with general policies determined by the Academy, the
Council has become the principal operating agency of both the National Academy
of Sciences and the National Academy of Engineering in providing services to
the government, the public, and the scientific and engineering communities. The
Council is administered jointly by both Academies and the Institute of Medicine.
Dr. Ralph J. Cicerone and Dr. Charles M. Vest are chair and vice chair, respectively,
of the National Research Council.
www.national-academies.org
Guide for the Care and
Guide
Use
forofthe
Laboratory
Care and
Guide
Animals,
Use
forofthe
Laboratory
8th
Care
edition.pdf
andAnimals,
Use of Laboratory
8th edition.pdf
Animals, 8th edition.pdf
, Guide for the Care and
Guide
Use
forofthe
Laboratory
Care and
Guide
Animals,
Use
forofthe
Laboratory
8th
Care
edition.pdf
andAnimals,
Use of Laboratory
8th edition.pdf
Animals, 8th edition.pdf
Guide for the Care and
Guide
Use
forofthe
Laboratory
Care and
Guide
Animals,
Use
forofthe
Laboratory
8th
Care
edition.pdf
andAnimals,
Use of Laboratory
8th edition.pdf
Animals, 8th edition.pdf
