ATI Fundamentals | PPE & Standard Precautions Practice Pack
2026/2027 |Questions |Answers |Rationales
1. A nurse is preparing to care for a client with Clostridium difficile. Which of the
following hand hygiene methods should the nurse use?
A. Alcohol-based hand rub
B. Soap and water
C. Chlorhexidine scrub
D. Hydrogen peroxide wipes
Answer: B
Rationale: Soap and water is required for C. diff because alcohol-based rubs are ineffective
against the spore-forming bacteria.
2. Which of the following is the correct order for donning Personal Protective
Equipment (PPE)?
A. Mask, Gown, Gloves, Goggles
B. Gloves, Goggles, Mask, Gown
C. Gown, Mask, Goggles, Gloves
D. Goggles, Mask, Gown, Gloves
Answer: C
Rationale: The recommended CDC sequence for donning PPE is gown, then mask or
respirator, then goggles or face shield, and finally gloves.
,3. A nurse is caring for a client who has Tuberculosis. What type of room should
this client be placed in?
A. Positive-pressure room
B. Semi-private room with a roommate who has the same diagnosis
C. Negative-pressure airflow room
D. Standard private room with the door open
Answer: C
Rationale: Clients with airborne infections like TB require a negative-pressure airflow
room with at least 6 to 12 air exchanges per hour.
4. When doffing PPE, which item should the nurse remove first?
A. Gloves
B. Mask
C. Gown
D. Goggles
Answer: A
Rationale: Gloves are considered the most contaminated and should be removed first to
prevent contaminating other items during doffing.
5. A nurse is caring for a client on Droplet Precautions. Which piece of PPE is
required at all times when within 3 feet of the client?
A. Surgical mask
B. N95 respirator
C. Gown
D. Shoe covers
Answer: A
Rationale: Droplet precautions require a surgical mask for anyone entering the room or
coming within 3 to 6 feet of the client.
, 6. Which diagnosis requires the use of Airborne Precautions?
A. Influenza
B. Varicella (Chickenpox)
C. Mycoplasma pneumonia
D. Vancomycin-resistant Enterococcus (VRE)
Answer: B
Rationale: Varicella, Measles, and Tuberculosis require airborne precautions, including an
N95 respirator and negative pressure room.
7. A nurse is about to irrigate a large open wound. Which PPE items are most
appropriate?
A. Gloves only
B. Gown, gloves, mask, and goggles
C. Gown, gloves, and mask
D. Gown and gloves only
Answer: B
Rationale: Wound irrigation carries a high risk of splashing; therefore, full protection
(gown, gloves, mask, and eye protection) is required.
8. Standard precautions should be applied to which of the following?
A. Only clients with known infections
B. Only clients in the ICU
C. All clients regardless of diagnosis
D. Only clients with bloodborne pathogens
Answer: C
Rationale: Standard precautions are the primary strategy for healthcare-associated
infection prevention and apply to all patients in all settings.
2026/2027 |Questions |Answers |Rationales
1. A nurse is preparing to care for a client with Clostridium difficile. Which of the
following hand hygiene methods should the nurse use?
A. Alcohol-based hand rub
B. Soap and water
C. Chlorhexidine scrub
D. Hydrogen peroxide wipes
Answer: B
Rationale: Soap and water is required for C. diff because alcohol-based rubs are ineffective
against the spore-forming bacteria.
2. Which of the following is the correct order for donning Personal Protective
Equipment (PPE)?
A. Mask, Gown, Gloves, Goggles
B. Gloves, Goggles, Mask, Gown
C. Gown, Mask, Goggles, Gloves
D. Goggles, Mask, Gown, Gloves
Answer: C
Rationale: The recommended CDC sequence for donning PPE is gown, then mask or
respirator, then goggles or face shield, and finally gloves.
,3. A nurse is caring for a client who has Tuberculosis. What type of room should
this client be placed in?
A. Positive-pressure room
B. Semi-private room with a roommate who has the same diagnosis
C. Negative-pressure airflow room
D. Standard private room with the door open
Answer: C
Rationale: Clients with airborne infections like TB require a negative-pressure airflow
room with at least 6 to 12 air exchanges per hour.
4. When doffing PPE, which item should the nurse remove first?
A. Gloves
B. Mask
C. Gown
D. Goggles
Answer: A
Rationale: Gloves are considered the most contaminated and should be removed first to
prevent contaminating other items during doffing.
5. A nurse is caring for a client on Droplet Precautions. Which piece of PPE is
required at all times when within 3 feet of the client?
A. Surgical mask
B. N95 respirator
C. Gown
D. Shoe covers
Answer: A
Rationale: Droplet precautions require a surgical mask for anyone entering the room or
coming within 3 to 6 feet of the client.
, 6. Which diagnosis requires the use of Airborne Precautions?
A. Influenza
B. Varicella (Chickenpox)
C. Mycoplasma pneumonia
D. Vancomycin-resistant Enterococcus (VRE)
Answer: B
Rationale: Varicella, Measles, and Tuberculosis require airborne precautions, including an
N95 respirator and negative pressure room.
7. A nurse is about to irrigate a large open wound. Which PPE items are most
appropriate?
A. Gloves only
B. Gown, gloves, mask, and goggles
C. Gown, gloves, and mask
D. Gown and gloves only
Answer: B
Rationale: Wound irrigation carries a high risk of splashing; therefore, full protection
(gown, gloves, mask, and eye protection) is required.
8. Standard precautions should be applied to which of the following?
A. Only clients with known infections
B. Only clients in the ICU
C. All clients regardless of diagnosis
D. Only clients with bloodborne pathogens
Answer: C
Rationale: Standard precautions are the primary strategy for healthcare-associated
infection prevention and apply to all patients in all settings.
