NUR 521 EXAM 2 EXAM WITH CORRECT
ACTUAL QUESTIONS AND CORRECTLY
WELL DEFINED ANSWERS LATEST
ALREADY GRADED A+
Spironolactone drug class - ANSWERS-Aldosterone
antagonist potassium-sparing diuretic
Spironolactone works in the - ANSWERS-works in the late
distal convoluted tubule and collecting duct (distal nephron)
Aldosterone acts to - ANSWERS-acts to promote sodium
uptake in exchange for potassium secretion
Aldosterone Antagonist acts to - ANSWERS-retention of
potassium and increased excretion of sodium
,Spironolactone MOA - ANSWERS-Blocks the actions of
aldosterone in the distal nephron causing the retention of
potassium and excretion of NA
Spironolactone produces modest... - ANSWERS-produces
modest increase in urine production
Spironolactone produces substantial - ANSWERS-produces
substantial decrease in potassium excretion
Spironolactone is often used to - ANSWERS-often used to
counteract potassium loss caused by thiazide and loop
diuretics, not usually used alone for diuresis
Spironolactone produces scanty diuresis because... -
ANSWERS-most NA has already been reabsorbed before
reaching the distal nephron
Spironolactone used with - ANSWERS-Used with HTN,
edema, CHF (blocking aldosterone creates protective
effects), used in combination to counteract K wasting drugs
,Spironolactone dosing - ANSWERS-25, 50, 100mg tablets,
25-200mg per day
Spironolactone works in - ANSWERS-48 hours (delayed
effects)
Spironolactone off label uses - ANSWERS-Off-label uses
include acne, hair loss, hirsutism, hormone therapy for
transgender females
Spironolactone adverse effects - ANSWERS-adverse effects
are hyperkalemia (dysrhythmia), endocrine effects
(gynecomastia, menstrual irregularities, impotence,
hirsutism, deep voice)
Spironolactone BBW - ANSWERS-BBW shown to cause
tumors in rats
Furosemide BBW - ANSWERS-BBW can cause profound
diuresis with water and electrolyte depletion
, Spironolactone interactions - ANSWERS-Caution with k
supplements or k sparing drugs (ACE-I. ARBs, Direct renin
inhibitors)
Triamterene - ANSWERS-Dyrenium
Triamterene drug class - ANSWERS-Non aldosterone
antagonist potassium sparing diuretic
Triamterene MoA - ANSWERS-Disrupts NA-K exchange in the
distal nephron by direct inhibition, Na excretion is increased
and K is conserved, minimal diuresis
Triamterene Dose - ANSWERS-50mg, 100mg works in a few
hours
Triamterene contraindications - ANSWERS-Contraindicated
with elevated K levels, caution with k sparing diuretics, k
supplements, ACE-I, ARBS, Direct renin inhibitor
Triamterene BBW - ANSWERS-BBW Hyperkalemia
ACTUAL QUESTIONS AND CORRECTLY
WELL DEFINED ANSWERS LATEST
ALREADY GRADED A+
Spironolactone drug class - ANSWERS-Aldosterone
antagonist potassium-sparing diuretic
Spironolactone works in the - ANSWERS-works in the late
distal convoluted tubule and collecting duct (distal nephron)
Aldosterone acts to - ANSWERS-acts to promote sodium
uptake in exchange for potassium secretion
Aldosterone Antagonist acts to - ANSWERS-retention of
potassium and increased excretion of sodium
,Spironolactone MOA - ANSWERS-Blocks the actions of
aldosterone in the distal nephron causing the retention of
potassium and excretion of NA
Spironolactone produces modest... - ANSWERS-produces
modest increase in urine production
Spironolactone produces substantial - ANSWERS-produces
substantial decrease in potassium excretion
Spironolactone is often used to - ANSWERS-often used to
counteract potassium loss caused by thiazide and loop
diuretics, not usually used alone for diuresis
Spironolactone produces scanty diuresis because... -
ANSWERS-most NA has already been reabsorbed before
reaching the distal nephron
Spironolactone used with - ANSWERS-Used with HTN,
edema, CHF (blocking aldosterone creates protective
effects), used in combination to counteract K wasting drugs
,Spironolactone dosing - ANSWERS-25, 50, 100mg tablets,
25-200mg per day
Spironolactone works in - ANSWERS-48 hours (delayed
effects)
Spironolactone off label uses - ANSWERS-Off-label uses
include acne, hair loss, hirsutism, hormone therapy for
transgender females
Spironolactone adverse effects - ANSWERS-adverse effects
are hyperkalemia (dysrhythmia), endocrine effects
(gynecomastia, menstrual irregularities, impotence,
hirsutism, deep voice)
Spironolactone BBW - ANSWERS-BBW shown to cause
tumors in rats
Furosemide BBW - ANSWERS-BBW can cause profound
diuresis with water and electrolyte depletion
, Spironolactone interactions - ANSWERS-Caution with k
supplements or k sparing drugs (ACE-I. ARBs, Direct renin
inhibitors)
Triamterene - ANSWERS-Dyrenium
Triamterene drug class - ANSWERS-Non aldosterone
antagonist potassium sparing diuretic
Triamterene MoA - ANSWERS-Disrupts NA-K exchange in the
distal nephron by direct inhibition, Na excretion is increased
and K is conserved, minimal diuresis
Triamterene Dose - ANSWERS-50mg, 100mg works in a few
hours
Triamterene contraindications - ANSWERS-Contraindicated
with elevated K levels, caution with k sparing diuretics, k
supplements, ACE-I, ARBS, Direct renin inhibitor
Triamterene BBW - ANSWERS-BBW Hyperkalemia
