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  • Peshawar Dental College
  • PHAR 243 (PHARMA)
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Lecture notes

Routes of drug administration

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13 pages
2025/2026 Written for academic year
Institution
Peshawar Dental College
Module
PHAR 243 (PHARMA)
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Covers all the method through which drug is administered Advantage and disadvantages of different methods of drug administration Summary table at the end

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Hereisastructuredpreviewofthepharmacologynotes
acrossthepagesprovided:
Topic:
IntroductiontoRoutesofAdministration
CoreConcepts:
Theselectedroutedetermineshowadrugisabsorbed
andwhetheritmustcrosscellmembranes.
EnteralRoute:InvolvesOralandRectaladministration.
ParenteralRoute(Injections): IncludesIntradermal(intothe
dermis)andSubcutaneous(intofattytissue).
Topic:
EnteralandOralRoutes
CoreConcepts:
Parenteralbreakdowncontinued:IM(intomuscles)and
IV(directlyintoveins).Otherroutesincludeinhaled,
topical,buccal,andsublingual.
EnteralRoute:
PlacingthedrugintoanypartoftheGastrointestinal
Tract(GIT).
OralRoute:

, Swallowingthedrugthroughthemouth.
Advantages: Mostcommon,safe,convenient,painless,
economical;nosterilizationrequired.
Disadvantages: Sloweronsetofaction;polardrugsarenot
absorbed;drugscanbedestroyedbydigestivejuices.
Topic:
OralTidbits,Rectal,andSublingual/BuccalRoutes
CoreConcepts:
Tidbit: Oraldrugsundergodegradationintheliverbefore
reachingsystemiccirculation(First-passeffect).
ContraindicationsforOral: Unconscious,uncooperative,or
vomitingpatients.
RectalRoute:
Focusesonsuppositoriesorenemas.Usefulforvomiting
patientsorgastric-irritantdrugs.
Tidbit: Bypasses50\%offirst-passmetabolismvia
externalhemorrhoidalvessels.
Sublingual:
Placedunderthetongue.Buccal:Crushed/placed
betweencheekandgums.
Advantages: Quickonsetduetohighvascularity;actioncan
beterminatedbyspittingoutthedrug
Connected book
image
Karen Whalen Lippincott Illustrated Reviews: Pharmacology
Publisher: 2018 ISBN: 9781496384133 Edition: Unknown

Document information

Uploaded on
June 27, 2026
Number of pages
13
Written in
2025/2026
Type
Lecture notes
Professor(s)
Dr amna
Contains
Only route of drug administration
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Subjects

  • how drugs are administered
  • explain routes of drugs administration
  • name the methods through which drugs are administ
  • which method of drug is preferred and why

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