Test Bank for Lippincott Illustrated Reviews: Pharmacology 7th Edition by Karen Whalen, Pharm.D., BCPS all 48 chapters

TESTBANK l




Lippincott Illustrated Reviews: Phar
l l l




macology7th EditionbyKaren Whale
l l l l l




n




TESTBANK l

,PharmacologylIllustratedlReviewsl7thlEditionlWhalenlTestlBanklTABLEl

OFlCONTENT
Chapterl1:lPharmacokinetics
Chapterl2:lDrug–ReceptorlInteractionslandlPharmacodynamics
Chapterl3:lThelAutonomiclNervouslSystem
Chapterl4:lCholinergiclAgonists
Chapterl5:lCholinergiclAntagonists
Chapterl6:lAdrenergiclAgonists
Chapterl7:lAdrenergiclAntagonists
Chapterl8:lDrugslforlNeurodegenerativelDiseases
Chapterl9:lAnxiolyticlandlHypnoticlDrugs
Chapterl10:lAntidepressants
Chapterl11:lAntipsychoticlDrugs
Chapterl12:lDrugslforlEpilepsy
Chapterl13:lAnesthetics
Chapterl14:lOpioids
Chapterl15:lDrugsloflAbuse
Chapterl16:lCNSlStimulants
Chapterl17:lAntihypertensives
Chapterl18:lDiuretics
Chapterl19:lHeartlFailure
Chapterl20:lAntiarrhythmics
Chapterl21:lAntianginallDrugs
Chapterl22:lAnticoagulantslandlAntiplateletlAgents
Chapterl23:lDrugslforlHyperlipidemia
Chapterl24:lPituitarylandlThyroid
Chapterl25:lDrugslforlDiabetes
Chapterl26:lEstrogenslandlAndrogens
Chapterl27:lAdrenallHormones
Chapterl28:lDrugslforlObesity
Chapterl29:lDrugslforlDisordersloflthelRespiratorylSystem
Chapterl30:lAntihistamines
Chapterl31:lGastrointestinallandlAntiemeticlDrugs
Chapterl32:lDrugslforlUrologiclDisorders
Chapterl33:lDrugslforlAnemia
Chapterl34:lDrugslforlDermatologiclDisorders
Chapterl35:lDrugslforlBonelDisorders
Chapterl36:lAnti-inflammatory,lAntipyretic,landlAnalgesiclAgents
Chapterl37:lPrinciplesloflAntimicrobiallTherapy
Chapterl38:lCelllWalllInhibitors
Chapterl39:lProteinlSynthesislInhibitors
Chapterl40:lQuinolones,lFoliclAcidlAntagonists,landlUrinarylTractlAntiseptics
Chapterl41:lAntimycobacteriallDrugs
Chapterl42:lAntifungallDrugs
Chapterl43:lAntiprotozoallDrugs
Chapterl44:lAnthelminticlDrugs
Chapterl45:lAntivirallDrugs
Chapterl46:lAnticancerlDrugs
Chapterl47:lImmunosuppressants
Chapterl48:lClinicallToxicology

, PharmacologylIllustratedlReviewsl7thlEditionlWhalenlT

estlBank

Chapterl1:lPharmacokineticslMU

LTIPLElCHOICE

1. lWhichldrugslwilllgolthroughlalpharmaceuticlphaselafterlitl isladministered?
a. Intramuscularlcephalosporins
b. Intravenouslvasopressors
c. Orallanalgesics
d. Subcutaneouslantiglycemicsl
ANS:lC
Whenldrugslareladministeredlparenterally,ltherelislnolpharmaceuticlphase,lwhichloccurslwhenlaldruglb
ecomeslalsolutionlthatlcanlcrosslthelbiologiclmembrane.

DIF:lCOGNITIVElLEVEL:lUnderstandingl(Comprehension)lREF:ldml3lTOP:l
NURSINGlPROCESS:lAssessment
MSC:lNCLEX:lPhysiologicallIntegrity:lPharmacologicallandlParenterallTherapies

2. Thelnurselislpreparingltoladministerlanlorallmedicationlandlwantsltolensurelalrapidldruglactio
n.lWhichlformloflthelmedicationlwilllthelnurseladminister?
a. Capsule
b. Enteric-coatedlpill
c. Liquidlsuspension
d. Tablet
ANS:lC
l


Liquidldrugslarelalreadylinlsolution,lwhichlislthelformlnecessarylforlabsorptionlinlthelGIltract.lThelo
therlformslmustldisintegratelintolsmalllparticleslandlthenldissolvelbeforelbeinglabsorbed.

DIF:lCOGNITIVElLEVEL:lUnderstandingl(Comprehension)lREF:ldml3lTOP:l
NURSINGlPROCESS:lNursinglIntervention
MSC:lNCLEX:lPhysiologicallIntegrity:lPharmacologicallandlParenterallTherapies

, Stuvia.coml-lThelMarketplaceltolBuylandlSelllyourlStudy




3. Thelnurselislteachinglalpatientlwholwilllbeldischargedlhomelwithlalprescriptionlforlanlenteric-
coatedltablet.lWhichlstatementlbylthelpatientlindicateslunderstandingloflthelteaching?
a. Ilmaylcrushltheltabletlandlputlitlinlapplesauceltolimprovelabsorption.
b. Ilshouldlconsumelacidiclfoodsltolenhancelabsorptionloflthislmedication.
c. Ilshouldlexpectlaldelaylinlonsetlofltheldrugsleffectslafterltakingltheltablet.
d. Ilshouldltakelthislmedicationlwithlhigh-
fatlfoodsltolimprovelitslaction.lANS:lC
Enteric-
coatedltabletslresistldisintegrationlinlthelacidiclenvironmentloflthelstomachlandldisintegratelwhenlthe
ylreachlthelsmalllintestine.lTherelislusuallylsomeldelaylinlonsetloflactionslafterltakingltheselmedicatio
ns.lEnteric-
coatedltabletslshouldlnotlbelcrushedlorlchewed,lwhichlwouldlalterltheltimelandllocationloflabsorption.
l Acidiclfoodslwilllnotlenhancelthelabsorptionloflthelmedication.lThelpatientlshouldlnotltoleatlhigh-
fatlfoodlbeforelingestinglanlenteric-coatedltablet,lbecauselhigh-
fatlfoodsldecreaselthelabsorptionlrate.

DIF:lCOGNITIVElLEVEL:lApplyingl(Application)lREF:ldml3lTOP:l
NURSINGlPROCESS:lNursinglIntervention
MSC:lNCLEX:lPhysiologicallIntegrity:lPharmacologicallandlParenterallTherapies

4. Alpatientlwholislnewlyldiagnosedlwithltypel1ldiabeteslmellituslaskslwhylinsulinlmustlbelgivenlbyl
subcutaneouslinjectionlinsteadloflbylmouth.lThelnurselwilllexplainlthatlthislislbecause
a. absorptionlisldiminishedlbylthelfirst-passleffectslinlthelliver.
b. absorptionlislfasterlwhenlinsulinlislgivenlsubcutaneously.
c. digestivelenzymeslinlthelgastrointestinalltractlpreventlabsorption.
d. thelorallformlisllesslpredictablelwithlmoreladverseleffects.lA
NS:lC
Insulin,lgrowthlhormones,landlotherlprotein-
basedldrugslareldestroyedlinlthelsmalllintestinelbyldigestivelenzymeslandlmustlbelgivenlparenterally.l
Becauselinsulinlisldestroyedlbyldigestivelenzymes,litlwouldlnotlmakelitltolthelliverlforlmetabolismlwit
hlalfirst-
passleffect.lSubcutaneousltissuelhaslfewerlbloodlvessels,lsolabsorptionlislslowerlinlsuchltissue.lInsulin
l islgivenlsubcutaneouslylbecauselitlisldesirableltolhavelitlabsorblslowly.

DIF:lCOGNITIVElLEVEL:lUnderstandingl(Comprehension)lREF:ldml3lTOP:l
NURSINGlPROCESS:lNursinglIntervention:lPatientlTeaching
MSC:lNCLEX:lPhysiologicallIntegrity:lPharmacologicallandlParenterallTherapies