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Mechanical Ventilation & Respiratory Failure 2026 Essentials

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1. A patient is placed on mechanical ventilation. Which parameter is most important for evaluating oxygenation? A. Serum creatinine B. SpO₂ (oxygen saturation) C. Blood glucose D. Urine output Correct Answer: B. SpO₂ (oxygen saturation) Rationale: SpO₂ directly reflects the effectiveness of oxygen delivery and ventilation support. 2. Which ABG finding is most consistent with acute respiratory failure? A. pH 7.40, PaCO₂ 40 mmHg B. pH 7.30, PaCO₂ 55 mmHg C. pH 7.45, PaCO₂ 35 mmHg D. pH 7.50, PaCO₂ 30 mmHg Correct Answer: B. pH 7.30, PaCO₂ 55 mmHg Rationale: Elevated CO₂ with acidemia indicates hypercapnic respiratory failure. 3. Which ventilator alarm requires immediate action? A. Low-pressure alarm B. High-pressure alarm C. Power-on alarm test D. Battery charging alarm Correct Answer: B. High-pressure alarm Rationale: High pressure may indicate obstruction, secretion buildup, or pneumothorax. 4. A patient on mechanical ventilation suddenly becomes hypotensive and tachycardic. What is the priority concern? A. Fluid overload B. Pneumothorax C. Hyperglycemia D. Kidney failure Correct Answer: B. Pneumothorax Rationale: Tension pneumothorax can occur and cause cardiovascular collapse. 5. Which finding suggests inadequate oxygenation in a ventilated patient? A. SpO₂ 98% B. Cyanosis C. Normal urine output D. Warm skin Correct Answer: B. Cyanosis Rationale: Cyanosis indicates poor oxygen delivery to tissues. 6. What is the primary purpose of PEEP (Positive End-Expiratory Pressure)? A. Decrease heart rate B. Prevent alveolar collapse C. Increase urine output D. Lower blood pressure Correct Answer: B. Prevent alveolar collapse Rationale: PEEP keeps alveoli open, improving gas exchange. 7. Which complication is most associated with prolonged mechanical ventilation? A. Hyperthyroidism B. Ventilator-associated pneumonia C. Appendicitis D. Cataracts Correct Answer: B. Ventilator-associated pneumonia Rationale: Intubation increases risk of lung infection. 8. A patient becomes agitated and fights the ventilator. What is the first nursing action? A. Increase sedation without order B. Assess oxygenation and airway patency C. Remove the endotracheal tube D. Turn off the ventilator Correct Answer: B. Assess oxygenation and airway patency Rationale: Agitation may indicate hypoxia or ventilator issues. 9. Which mode of ventilation supports every breath the patient initiates? A. Assist-control ventilation B. CPAP only C. Room air breathing D. Oxygen mask Correct Answer: A. Assist-control ventilation Rationale: Assist-control delivers full support to all patient-triggered breaths.

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1.​ A patient is placed on mechanical ventilation. Which parameter is most important for
evaluating oxygenation?

A. Serum creatinine​
B. SpO₂ (oxygen saturation)​
C. Blood glucose​
D. Urine output

Correct Answer: B. SpO₂ (oxygen saturation)

Rationale: SpO₂ directly reflects the effectiveness of oxygen delivery and ventilation support.



2.​ Which ABG finding is most consistent with acute respiratory failure?

A. pH 7.40, PaCO₂ 40 mmHg​
B. pH 7.30, PaCO₂ 55 mmHg​
C. pH 7.45, PaCO₂ 35 mmHg​
D. pH 7.50, PaCO₂ 30 mmHg

Correct Answer: B. pH 7.30, PaCO₂ 55 mmHg

Rationale: Elevated CO₂ with acidemia indicates hypercapnic respiratory failure.



3.​ Which ventilator alarm requires immediate action?

A. Low-pressure alarm​
B. High-pressure alarm​
C. Power-on alarm test​
D. Battery charging alarm

Correct Answer: B. High-pressure alarm

Rationale: High pressure may indicate obstruction, secretion buildup, or pneumothorax.



4.​ A patient on mechanical ventilation suddenly becomes hypotensive and tachycardic.
What is the priority concern?

A. Fluid overload​
B. Pneumothorax​

,C. Hyperglycemia​
D. Kidney failure

Correct Answer: B. Pneumothorax

Rationale: Tension pneumothorax can occur and cause cardiovascular collapse.



5.​ Which finding suggests inadequate oxygenation in a ventilated patient?

A. SpO₂ 98%​
B. Cyanosis​
C. Normal urine output​
D. Warm skin

Correct Answer: B. Cyanosis

Rationale: Cyanosis indicates poor oxygen delivery to tissues.



6.​ What is the primary purpose of PEEP (Positive End-Expiratory Pressure)?

A. Decrease heart rate​
B. Prevent alveolar collapse​
C. Increase urine output​
D. Lower blood pressure

Correct Answer: B. Prevent alveolar collapse

Rationale: PEEP keeps alveoli open, improving gas exchange.



7.​ Which complication is most associated with prolonged mechanical ventilation?

A. Hyperthyroidism​
B. Ventilator-associated pneumonia​
C. Appendicitis​
D. Cataracts

Correct Answer: B. Ventilator-associated pneumonia

Rationale: Intubation increases risk of lung infection.

, 8.​ A patient becomes agitated and fights the ventilator. What is the first nursing action?

A. Increase sedation without order​
B. Assess oxygenation and airway patency​
C. Remove the endotracheal tube​
D. Turn off the ventilator

Correct Answer: B. Assess oxygenation and airway patency

Rationale: Agitation may indicate hypoxia or ventilator issues.



9.​ Which mode of ventilation supports every breath the patient initiates?

A. Assist-control ventilation​
B. CPAP only​
C. Room air breathing​
D. Oxygen mask

Correct Answer: A. Assist-control ventilation

Rationale: Assist-control delivers full support to all patient-triggered breaths.



10.​Which ABG value indicates respiratory acidosis?

A. pH 7.50, PaCO₂ 30​
B. pH 7.25, PaCO₂ 60​
C. pH 7.45, PaCO₂ 35​
D. pH 7.40, PaCO₂ 40

Correct Answer: B. pH 7.25, PaCO₂ 60

Rationale: CO₂ retention lowers pH causing respiratory acidosis.



11.​Which action helps prevent ventilator-associated pneumonia (VAP)?

A. Keep patient supine​
B. Elevate head of bed 30–45°​
C. Limit oral care​
D. Reduce suctioning

Correct Answer: B. Elevate head of bed 30–45°

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