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PANCE Board Review & CME 2026 – Practice Questions and Study Guide

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This document provides a comprehensive PANCE (Physician Assistant National Certifying Exam) board review with CME practice questions. It covers core medical topics, clinical scenarios, and detailed answer explanations to help learners reinforce knowledge, assess readiness, and prepare effectively for the PANCE exam and continuing medical education requirements. Ideal for structured review, self-assessment, and exam preparation.

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PANCE Board Review & CME 2026 – Practice Questions and Study
Guide


which antiHTN class frequently causes constipation &/or peripheral edema? - ANS✔✔ CCBs

[-dipine]



what would you see on the EKG in prinzmetal [aka vasospasm] angina? - ANS✔✔ ST elevation



50y/o woman w/ CP & ST elevation w/o infarction when she went to the cath lab - ANS✔✔
*coronary vasospasm*

- BB: not a tx for this form of CAD



acute coronary syndrome = - ANS✔✔ unstable angina = nonSTEMI



JNC 9

JNC 8 - ANS✔✔ 130/80

140/90



a patient w/ a significant lateral MI should have ST elevation in which leads - ANS✔✔



which abx is best to use against infections by anaerobic organisms? - ANS✔✔ - erythromycin

- penicillin

- ceftriaxone

- *clindamycin*



which, in high doses is assoc w/ loss of red-green color & optic neuritis - ANS✔✔ ethambutol

,which abx should NOT be used in pregnancy - ANS✔✔ - aminoglycosides & clindamycin



which is an andipseudomonal penicillin - ANS✔✔ - nafcillin *[AE = interstitial nephritis]*

- oxacillin

- dicloxacillin

- *piperacillin* [IV?]



listeria abx tx = - ANS✔✔ ampicillin



which antiviral is th most effective for tx of CMV? - ANS✔✔ Ganicyclovir



which thyroid carcinoma is most common? - ANS✔✔ - medullary

- follicular

- *papillary*

- anapestic



which best explains the Somogyi effect - ANS✔✔ - d/t relative insulin excess in the morning

- d/t deficiency @ midnight

- *d/t rebound nocturnal hypoglycemia*



which serologic test should be initially ordered if you suspect PRIMARY hypOthyroidism? -
ANS✔✔ - serum T4

- serum T3

- free T4

- *TSH*

, glucocorticoids are known to do all the following EXCEPT - ANS✔✔ - cause hyperglycemia

- cause euphoria

- decrease TST & LH

- *decreased IOP--> [it INCREASES IOP]*



a schiz. pt is taking geodon. which late abnormality is most worrisome in this patient? - ANS✔✔
hypOcalcemia bc geodon has a risk for long QT



which lab value is assoc. w/ Cushing's? - ANS✔✔ elevated ACTH



22 y/o college student complains of persistent bilateral rhinorrhea & nasal congestion for the
past month. she's been using OTC Afrin that initially seemed to help. diagnosis? - ANS✔✔
rhinitis medica



a pt w/ episodic vertigo, HL, tinnitus, & sensation of aural pressure has the dx of ___ - ANS✔✔ -
BPPV

- menneires dz

-

-



Ramsey-Hunt syndrome is an otitis externa w/ which CN palsy? - ANS✔✔ facial- CN VII



college student comes to ER w/ severe throat pain & dysphagia. on initial exam- *fever truisms
& muffled voice*. before looking at his pharynx, you already suspect ___ - ANS✔✔ -
*peritonsilar abscess*

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