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ULTIMATE HESI PHARMACOLOGY EXAM SUCCESS BANK

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Master Pharmacology with Confidence! This comprehensive exam bank contains TWO complete versions of the HESI Pharmacology exam with detailed, verified answers and rationales for every single question. Each answer includes clinical reasoning, drug classifications, side effects, nursing interventions, and patient teaching points that mirror actual exam content.

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HESI Pharmacology Exam Practice TEST FINAL EXAM AND
PRACTICE EXAM 20262027 BANK 2 VERSIONS QUESTIONS
WITH DETAILED VERIFIED ANSWERS EXAM QUESTIONS
WILL COME FROM HERE (100% CORRECT ANSWERS A+
GRADED




A healthcare provider prescribes cephalexin monohydrate (Keflex) for a
client with a postoperative infection. It is most important for the nurse
to assess for what additional drug allergy before administering this
prescription?
A) Penicillins.
B) Aminoglycosides.
C) Erythromycins.
D) Sulfonamides. - ANSWER--A) Penicillins.


Cross-allergies exist between penicillins (A) and cephalosporins, such as
cephalexin monohydrate (Keflex), so checking for penicillin allergy is a
wise precaution before administering this drug.


Which nursing intervention is most important when caring for a client
receiving the antimetabolite cytosine arabinoside (Arc-C) for
chemotherapy?
A) Hydrate the client with IV fluids before and after infusion.

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B) Assess the client for numbness and tingling of extremities.
C) Inspect the client's oral mucosa for ulcerations.
D) Monitor the client's urine pH for increased acidity. - ANSWER--C)
Inspect the client's oral mucosa for ulcerations.


Cytosine arabinoside (Arc-C) affects the rapidly growing cells of the
body, therefore stomatitis and mucosal ulcerations are key signs of
antimetabolite toxicity (C). (A, B, and D) are not typical interventions
associated with the administration of antimetabolites.


When assessing an adolescent who recently overdosed on
acetaminophen (Tylenol), it is most important for the nurse to assess
for pain in which area of the body?
A) Flank.
B) Abdomen.
C) Chest.
D) Head. - ANSWER--B) Abdomen.


Acetaminophen toxicity can result in liver damage; therefore, it is
especially important for the nurse to assess for pain in the right upper
quadrant of the abdomen (B), which might indicate liver damage. (A, C,
and D) are not areas where pain would be anticipated.

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An adult client is given a prescription for a scopolamine patch
(Transderm Scop) to prevent motion sickness while on a cruise. Which
information should the nurse provide to the client?
A) Apply the patch at least 4 hours prior to departure.
B) Change the patch every other day while on the cruise.
C) Place the patch on a hairless area at the base of the skull.
D) Drink no more than 2 alcoholic drinks during the cruise. - ANSWER--
A) Apply the patch at least 4 hours prior to departure.


Scopolamine, an anticholinergic agent, is used to prevent motion
sickness and has a peak onset in 6 hours, so the client should be
instructed to apply the patch at least 4 hours before departure (A) on
the cruise ship. The duration of the transdermal patch is 72 hours, so
(B) is not needed. Scolopamine blocks muscarinic receptors in the inner
ear and to the vomiting center, so the best application site of the patch
is behind the ear, not at the base of the skull (C). Anticholinergic
medications are CNS depressants, so the client should be instructed to
avoid alcohol (D) while using the patch.


The nurse is reviewing the use of the patient-controlled analgesia (PCA)
pump with a client in the immediate postoperative period. The client
will receive morphine 1 mg IV per hour basal rate with 1 mg IV every 15
minutes per PCA to total 5 mg IV maximally per hour. What assessment
has the highest priority before initiating the PCA pump?
A) The expiration date on the morphine syringe in the pump.
B) The rate and depth of the client's respirations.

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C) The type of anesthesia used during the surgical procedure.
D) The client's subjective and objective signs of pain. - ANSWER--B) The
rate and depth of the client's respirations.


A life-threatening side effect of intravenous administration of morphine
sulfate, an opiate narcotic, is respiratory depression (B). The PCA pump
should be stopped and the healthcare provider notified if the client's
respiratory rate falls below 12 breaths per minute, and the nurse
should anticipate adjustments in the client's dosage before the PCA
pump is restarted. (A, C, and D) provide helpful information, but are not
as high a priority as the assessment described in (B).


A medication that is classified as a beta-1 agonist is most commonly
prescribed for a client with which condition?
A) Glaucoma.
B) Hypertension.
C) Heart failure.
D) Asthma. - ANSWER--C) Heart failure.


Beta-1 agonists improve cardiac output by increasing the heart rate and
blood pressure and are indicated in heart failure (C), shock,
atrioventricular block dysrhythmias, and cardiac arrest. Glaucoma (A) is
managed using adrenergic agents and beta-adrenergic blocking agents.
Beta-1 blocking agents are used in the management of hypertension
(B). Medications that stimulate beta-2 receptors in the bronchi are

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