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Pharmacology HESI Comprehensive Review for the NCLEX-PN
Exam, 6th Edition TEST FINAL EXAM AND PRACTICE EXAM
2026/2027 BANK 2 VERSIONS QUESTIONS WITH DETAILED
VERIFIED ANSWERS / EXAM QUESTIONS WILL COME
FROM HERE (100% CORRECT ANSWERS/ A+ GRADED
A client who received a prescription for cyclosporine ophthalmic
emulsion for dry eyes asks the practical nurse (PN) if it is safe to
continue using artificial tears. What information should the PN provide?
a. Avoid the use of artificial tears because they decrease the efficacy of
cyclosporine.
b. Discontinue the use of both products if transient blurring occurs after
administration.
c. Allow a 15-minute interval between the administration of
cyclosporine and artificial tears.
d. Discontinue the use of cyclosporine and artificial tears when tear
production reaches a normal level. - ANSWERS--c. Allow a 15-minute
interval between the administration of cyclosporine and artificial tears.
Rationale:
Cyclosporine, an ophthalmic emulsion which increases tear production,
may be used in conjunction with artificial tears as long as the products
are administered 15 minutes apart. Transient blurring after
administration is a side effect of cyclosporine and does not necessitate
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discontinuation of the medication. After tear production is increased,
artificial tears may be stopped, but discontinuing cyclosporine will
result in a decrease in tear production.
A first-day postoperative client vomits 30 minutes after receiving a dose
of hydromorphone. What initial intervention is best for the practical
nurse (PN) to implement?
a. Obtain a prescription for nasogastric intubation.
b. Administer a prn dose of ondansetron.
c. Reduce the next scheduled dose of hydromorphone.
d. Assess the client's abdomen and bowel sounds. - ANSWERS--b.
Administer a prn dose of ondansetron.
Rationale:
Because the emesis appears to be directly related to the administration
of the opiate analgesic, the first action should be to reduce the client's
nausea with the administration of the ondansetron, which is an
antiemetic.
A client has been prescribed losartan. Which change in data indicates to
the practical nurse (PN) that the desired effect of this medication has
been achieved?
a. Dependent edema reduced from +3 to +1.
b. Serum HDL increased from 35 to 55 mg/dL.
c. Pulse rate reduced from 150 to 90 beats/min.
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d. Blood pressure reduced from 160/90 to 130/80 mm Hg. - ANSWERS--
d. Blood pressure reduced from 160/90 to 130/80 mm Hg.
Rationale:
Losartan is prescribed for the treatment of hypertension. The desired
effect is a decrease in blood pressure.
A child is admitted to the emergency department for accidental
ingestion of a poison. The practical nurse (PN) should know that
inducing vomiting is recommended for which child?
a. An 8 month old who ate four to six ibuprofen tablets
b. A 3 year old who drank an unknown amount of charcoal lighter fluid
c. A 16 month old who drank 2 ounces of acetaminophen elixir
d. A 2 year old who ate a handful of automatic dishwasher detergent -
ANSWERS--c. A 16 month old who drank 2 ounces of acetaminophen
elixir
Rationale:
Emesis should be induced for the child who drank the large dose of
acetaminophen elixir because this medication is hepatotoxic. Vomiting
is contraindicated for children younger than 1 year of age. Inducing
vomiting of corrosives such as dishwasher detergents and lighter fluid is
contraindicated.
A practical nurse (PN) is reviewing teaching with the client and/or
significant others about the concurrent use of benztropine and
olanzapine to manage psychotic behavior. What information should the
PN reinforce?
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a. Benztropine will reduce the olanzapine's side effect of urinary
retention.
b. Benztropine potentiates the effect of olanzapine.
c. The benztropine is used to control the side effects of olanzapine.
d. The combined effect of these drugs will modify psychotic behavior. -
ANSWERS--c. The benztropine is used to control the side effects of
olanzapine.
Rationale:
Benztropine, an anticholinergic drug, is used to control extrapyramidal
symptoms associated with olanzapine use. Caution is required in the
dosage of benztropine used in conjunction with olanzapine.
A client diagnosed with a herniated disc is prescribed
hydrocodone/acetaminophen 10 mg/300 mg prn every 4 to 6 hours. As
the practical nurse (PN) enters the client's room to administer their
requested medication, the client is seen talking and laughing with his
visiting family. Which action should the PN implement?
a. Hold the pain medication until after the visitors leave.
b. Notify the health care provider of the client's drug-seeking behavior.
c. Administer analgesia as requested by the client.
d. Inform the client based on their display behavior, the medication is
not needed. - ANSWERS--c. Administer analgesia as requested by the
client.
Rationale:
Pharmacology HESI Comprehensive Review for the NCLEX-PN
Exam, 6th Edition TEST FINAL EXAM AND PRACTICE EXAM
2026/2027 BANK 2 VERSIONS QUESTIONS WITH DETAILED
VERIFIED ANSWERS / EXAM QUESTIONS WILL COME
FROM HERE (100% CORRECT ANSWERS/ A+ GRADED
A client who received a prescription for cyclosporine ophthalmic
emulsion for dry eyes asks the practical nurse (PN) if it is safe to
continue using artificial tears. What information should the PN provide?
a. Avoid the use of artificial tears because they decrease the efficacy of
cyclosporine.
b. Discontinue the use of both products if transient blurring occurs after
administration.
c. Allow a 15-minute interval between the administration of
cyclosporine and artificial tears.
d. Discontinue the use of cyclosporine and artificial tears when tear
production reaches a normal level. - ANSWERS--c. Allow a 15-minute
interval between the administration of cyclosporine and artificial tears.
Rationale:
Cyclosporine, an ophthalmic emulsion which increases tear production,
may be used in conjunction with artificial tears as long as the products
are administered 15 minutes apart. Transient blurring after
administration is a side effect of cyclosporine and does not necessitate
,2|Page
discontinuation of the medication. After tear production is increased,
artificial tears may be stopped, but discontinuing cyclosporine will
result in a decrease in tear production.
A first-day postoperative client vomits 30 minutes after receiving a dose
of hydromorphone. What initial intervention is best for the practical
nurse (PN) to implement?
a. Obtain a prescription for nasogastric intubation.
b. Administer a prn dose of ondansetron.
c. Reduce the next scheduled dose of hydromorphone.
d. Assess the client's abdomen and bowel sounds. - ANSWERS--b.
Administer a prn dose of ondansetron.
Rationale:
Because the emesis appears to be directly related to the administration
of the opiate analgesic, the first action should be to reduce the client's
nausea with the administration of the ondansetron, which is an
antiemetic.
A client has been prescribed losartan. Which change in data indicates to
the practical nurse (PN) that the desired effect of this medication has
been achieved?
a. Dependent edema reduced from +3 to +1.
b. Serum HDL increased from 35 to 55 mg/dL.
c. Pulse rate reduced from 150 to 90 beats/min.
,3|Page
d. Blood pressure reduced from 160/90 to 130/80 mm Hg. - ANSWERS--
d. Blood pressure reduced from 160/90 to 130/80 mm Hg.
Rationale:
Losartan is prescribed for the treatment of hypertension. The desired
effect is a decrease in blood pressure.
A child is admitted to the emergency department for accidental
ingestion of a poison. The practical nurse (PN) should know that
inducing vomiting is recommended for which child?
a. An 8 month old who ate four to six ibuprofen tablets
b. A 3 year old who drank an unknown amount of charcoal lighter fluid
c. A 16 month old who drank 2 ounces of acetaminophen elixir
d. A 2 year old who ate a handful of automatic dishwasher detergent -
ANSWERS--c. A 16 month old who drank 2 ounces of acetaminophen
elixir
Rationale:
Emesis should be induced for the child who drank the large dose of
acetaminophen elixir because this medication is hepatotoxic. Vomiting
is contraindicated for children younger than 1 year of age. Inducing
vomiting of corrosives such as dishwasher detergents and lighter fluid is
contraindicated.
A practical nurse (PN) is reviewing teaching with the client and/or
significant others about the concurrent use of benztropine and
olanzapine to manage psychotic behavior. What information should the
PN reinforce?
, 4|Page
a. Benztropine will reduce the olanzapine's side effect of urinary
retention.
b. Benztropine potentiates the effect of olanzapine.
c. The benztropine is used to control the side effects of olanzapine.
d. The combined effect of these drugs will modify psychotic behavior. -
ANSWERS--c. The benztropine is used to control the side effects of
olanzapine.
Rationale:
Benztropine, an anticholinergic drug, is used to control extrapyramidal
symptoms associated with olanzapine use. Caution is required in the
dosage of benztropine used in conjunction with olanzapine.
A client diagnosed with a herniated disc is prescribed
hydrocodone/acetaminophen 10 mg/300 mg prn every 4 to 6 hours. As
the practical nurse (PN) enters the client's room to administer their
requested medication, the client is seen talking and laughing with his
visiting family. Which action should the PN implement?
a. Hold the pain medication until after the visitors leave.
b. Notify the health care provider of the client's drug-seeking behavior.
c. Administer analgesia as requested by the client.
d. Inform the client based on their display behavior, the medication is
not needed. - ANSWERS--c. Administer analgesia as requested by the
client.
Rationale:
