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Exam (elaborations)

: Clinical Immunology and Serology: A Laboratory Perspective (5th Edition) – Comprehensive Test Bank with Multiple-Choice Questions and Answers

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This document contains a comprehensive test bank for Clinical Immunology and Serology: A Laboratory Perspective (5th Edition) by Christine Dorresteyn. It includes multiple-choice questions and answers covering major topics such as innate and adaptive immunity, antigens and MHC, immunoglobulins, complement, T- and B-cell function, and antiglobulin testing. The material is organized by chapter and is designed for exam preparation, practice assessments, and review of key immunology and serology concepts used in clinical laboratory science.

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Chapter 1. Introduction to
Immunity and the Immune
System
Multiple Choice




Kareh
1. Eosinophils are involved in the immune response against:
A. viruses.
B. intracellular bacteria. e h
C. parasites that cannot be phagocytized.
D. extracellular bacteria.

ANS: C a r
2. Which of the following are components of both innate and adaptive immune responses?
A. Immunoglobulins
B. T helper cells
K
C. Macrophages
D. B cells

ANS: C



3. The process by which leukocytes are attracted to a specific area by chemical messengers is called:
A. diapedesis.
B. degranulation.
C. chemotaxis.
D. opsonization.

ANS: C



4. Which of the following is a characteristic of natural killer cells?
A. They mature in the thymus.
B. They are smaller than B and T cells.
C. They are a type of lymphocyte.
D. They are part of the adaptive immune system.

,ANS: C



5. Which of the following best describes diapedesis?
A. Movement toward increasing concentrations of a cytokine
B. Attachment of immunoglobulin to target cells




Kareh e h
a r
K

,C. Movement through blood vessel walls as cells exit the circulation
D. Engulfment of target cells

ANS: C



6. The most effective phagocytic and antigen-presenting cell is the:
A. neutrophil.
B. monocyte.
C. dendritic cell.
D. macrophage.

ANS: C




Kareh
A. It involves memory.
B. T lymphocytes play a major role.
e h
7. Which of the following is characteristic of natural immunity?


C. It involves specificity.
D. Mechanisms are always present and fully functional.

ANS: D a r
8. All of the following cells are considered part of natural immunity EXCEPT:
A. eosinophils.
B. B lymphocytes.
K
C. monocytes.
D. neutrophils.

ANS: B



9. Where does the specific immune response to a foreign antigen mainly occur?
A. Lymph nodes
B. Blood
C. Bone marrow
D. Skin

ANS: A



10. Which white cell in the peripheral blood migrates into tissue to become a macrophage?
A. Eosinophil
B. Basophil
C. Neutrophil

, D. Monocyte

ANS: D



11. A white blood cell that is 16 to 18 micrometers in diameter, has a horseshoe-shaped nucleus, and is
capable of phagocytosis is a:
A. neutrophil.
B. eosinophil.
C. basophil.
D. monocyte.

ANS: D




Kareh
h
12. Pasteur's discovery that older bacterial cultures would not cause disease in chickens but would protect
them from subsequent infection with more virulent strains is an example of:
A. attenuated vaccine.
e
B. natural immunity.
C. passive immunity.
D. cross-immunity.
r
ANS: A

K a
13. Antibodies are secreted by:
A. plasma cells.
B. B cells.
C. T cells.
D. dendritic cells.

ANS: A



14. Which of the following is characteristic of mucosal-associated lymphoid tissue?
A. It is one of the primary lymphoid organs.
B. It clears pathogens from the bloodstream.
C. It includes the tonsils and the appendix.
D. It includes the liver and spleen.

ANS: C



15. Acquired (adaptive) immunity can be characterized as:
A. nonspecifically activated.
B. immediately responsive.

Document information

Uploaded on
March 7, 2026
Number of pages
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Written in
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Type
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