Test Bank For Clayton’s Basic Pharmacology for Nurses 19th EditionB
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y Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton Comple
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te
,Chapter 01: Drug Definitions, Standards, and Information Sources Willihngan
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z: Clayton’s Basic Pharmacology for Nurses, 19th Edition
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MULTIPLE CHOICE $r
1. Which name identifies a drug listed by the US Food an
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dDrug Administration (FDA)?
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a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C $r
The official name is the name under which a drug is listed
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by the FDA. The brand name, or trademark, is the name gi
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ven to a drug by its manufacturer. The nonproprietary, or g
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eneric, name is provided by the United States Adopted Na
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mes Council. $r
DIF: Cognitive Level: Knowledge REF: p. 9 $r $r $r $r
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Car
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eEnvironment TOP: Nursing Process Step: Assessment
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CON: $r
Patient Education $r
2. Which source contains information specific to nutritional supplements?
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a. USP Dictionary of USAN &International Drug Names
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b. Natural Medicines Comprehensive Database $r $r $r
c. United States Pharmacopoeia/National Formulary (USP NF)
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d. Drug Interaction Facts $r $r
ANS: C $r
United States Pharmacopoeia/National Formulary contains information specific to nutritional
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$
supplements. USP Dictionary of USAN & International Drug Names is a compilation of dru
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gnames, pronunciation guide, and possible future FDA approved drugs; it does not include n
r
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utritional supplements. Natural Medicines Comprehensive Database contains
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evidence-
based information on herbal medicines and herbal combination products; it does notinclude in
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$ $r
formation specific to nutritional supplements. Drug Interaction Facts contains comprehensiv
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e information on drug interaction facts; it does not include nutritional supplements.
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DIF: Cognitive Level: Knowledge REF: p. 4 $r $r $ r $r
OBJ: 3NAT: NCLEX Client Needs Category: Physiological Inte
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grity
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
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3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
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a. Drug Facts and Comparisons $r $r $r
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Editi
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on
b. Drug Interaction Facts $r $r
c. Handbook on Injectable Drugs $r $r $r
d. Martindale—The Complete Drug Reference $r $r $r
ANS: A $r
Drug Facts and Comparisons contains drug monographs that describe all drugs in at
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herapeutic class. Monographs are formatted as tables to allow comparison of similarp
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roducts, brand names, manufacturers, cost indices, and available dosage forms Onlin
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e version is available.
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DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 $r $r $ r $r $r $r
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
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4. Which drug reference contains monographs about virtually every single-
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entity drug availablein the United States and describes therapeutic uses of drugs, including
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approved and unapproved uses? $r $r $r
a. Martindale: The Complete Drug Reference $r $r $r $r
b. AHFS Drug Information $r $r
c. Drug Reference $r
d. Drug Facts and Comparisons $r $r $r
ANS: B $r
AHFS Drug Information contains monographs about virtually every single-
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entity drug available in the United States and describes therapeutic uses of drugs, including ap
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proved andunapproved uses. $r $r $r
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 $r $r $ r $r $r $r
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Planning
$ r CON: Safety | Patient Education | Clinical Judgment
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5. Which online drug reference makes available to healthcare providers and the public a sta
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ndard, comprehensive, up-to-date look up and downloadable resource about medicines?
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a. American Drug Index $r $r
b. American Hospital Formulary $r $r
c. DailyMed
d. Drug Reference $r
ANS: C $r
DailyMed makes available to healthcare providers and the public a standard, comprehensive,
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up-to-
date look up and downloadable resource about medicines. The American Drug Index isnot ap
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$ $r
propriate for patient use. The American Hospital Formulary is not appropriate for patient u
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se. The drug reference is not appropriate for patient use.
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DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 $r $r $ r $r $r $r $r
OBJ: 3NAT: NCLEX Client Needs Category: Physiological Inte
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grity
TOP: Nursing Process Step: Implementation
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CON: Safety | Patient Education | Clinical Judgment
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6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
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a. Federal Food, Drug, and Cosmetic Act (1938) $r $r $r $r $r $r
b. Durham Humphrey Amendment (1952) $r $r $r
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Editi
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on
c. Controlled Substances Act (1970) $r $r $r
d. Kefauver Harris Drug Amendment (1962) $r $r $r $r
ANS: A $r
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the saf
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ety of all drugs before marketing. Later amendments and acts helped tighten FDA control an
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d ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that ca
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nnot be used safely without medical supervision and restricts their sale to prescription by a li
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censed practitioner. The Controlled Substances Act addresses only controlled substances andt
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$
heir categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater
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$
drug safety. Drug manufacturers are required to prove to the FDA the effectiveness of their
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products before marketing them. $r $r $r
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 $r $r $r $r $r $r
OBJ: 5 $ r
NAT: NCLEX Client Needs Category: Physiological Integrit $r $r $r $r $r $r
yTOP: Nursing Process Step: Assessment
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$ $r $r $r $r
CON: Safety | Patient Education | Evidence | Health Care Law
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7. Which classification does meperidine (Demerol) fall under?
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a. I
b. II
c. III
d. IV
ANS: B $r
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead t
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osevere psychological and physical dependence. Schedule I drugs have high potential for abus
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eand no recognized medical use. Schedule III drugs have some potential for abuse. Use may
r
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lead to low to moderate physical dependence or high psychological dependence. Schedule I
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Vdrugs have low potential for abuse. Use may lead to limited physical or psychological dep
r
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endence.
DIF: Cognitive Level: Knowledge REF: p. 10 $r $r $ r $r
OBJ: 2NAT: NCLEX Client Needs Category: Safe, Effective Car $r $r $r $r $r $r $r $r $r
e Environment
$r
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
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8. Which action would the FDA take to expedite drug development and approval for an outbreak
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of smallpox?
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a. List smallpox as a health orphan disease.
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b. Omit the preclinical research phase. $r $r $r $r
c. Extend the clinical research phase. $r $r $r $r
d. Fast track the investigational drug. $r $r $r $r
ANS: D $r
Once the Investigational New Drug Application has been approved, the drug can receive hig
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hest priority within the agency, which is called fast tracking. A smallpox outbreak would be
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come a priority concern in the world. Orphan diseases are not researched in a priority manne
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r. Preclinical research is not omitted. Extending any phase of the research would meana long
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er time to develop a vaccine. The FDA must ensure that all phases of the preclinical andclinica
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l research phase have been completed in a safe manner.
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DIF: Cognitive Level: Knowledge $r $r REF: p. 7 $r$r$r $r OBJ: 5 $r
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$
y Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton Comple
$r $r $r $r $r $r $r $r $r
te
,Chapter 01: Drug Definitions, Standards, and Information Sources Willihngan
$r $r $r $r $r $r $r $r
z: Clayton’s Basic Pharmacology for Nurses, 19th Edition
$r $r $r $r $r $r $r
MULTIPLE CHOICE $r
1. Which name identifies a drug listed by the US Food an
$r $r $r $r $r $r $r $r $r $r
dDrug Administration (FDA)?
r
$ $r $r
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C $r
The official name is the name under which a drug is listed
$r $r $r $r $ r $r $r $r $r $r $r $
by the FDA. The brand name, or trademark, is the name gi
r $r $r $r $r $r $r $r $r $r $r $r
ven to a drug by its manufacturer. The nonproprietary, or g
$r $r $r $r $r $r $r $r $r $r
eneric, name is provided by the United States Adopted Na
$r $r $r $r $r $r $r $r $r
mes Council. $r
DIF: Cognitive Level: Knowledge REF: p. 9 $r $r $r $r
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Car
$r $r $r $r $r $r $r $r
eEnvironment TOP: Nursing Process Step: Assessment
r
$ $r $ r $r $r $r
CON: $r
Patient Education $r
2. Which source contains information specific to nutritional supplements?
$r $r $r $r $r $r $r
a. USP Dictionary of USAN &International Drug Names
$r $r $r $r $r $r $r
b. Natural Medicines Comprehensive Database $r $r $r
c. United States Pharmacopoeia/National Formulary (USP NF)
$r $r $r $r $r
d. Drug Interaction Facts $r $r
ANS: C $r
United States Pharmacopoeia/National Formulary contains information specific to nutritional
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$
supplements. USP Dictionary of USAN & International Drug Names is a compilation of dru
$r $r $r $r $r $r $r $r $r $r $r $r $r
gnames, pronunciation guide, and possible future FDA approved drugs; it does not include n
r
$ $r $r $r $r $r $r $r $r $r $r $r $r $r
utritional supplements. Natural Medicines Comprehensive Database contains
$r $r $r $r $r $r
evidence-
based information on herbal medicines and herbal combination products; it does notinclude in
$r $r $r $r $r $r $r $r $r $r $r r
$ $r
formation specific to nutritional supplements. Drug Interaction Facts contains comprehensiv
$r $r $r $r $r $r $r $r $r
e information on drug interaction facts; it does not include nutritional supplements.
$r $r $r $r $r $r $r $r $r $r $r
DIF: Cognitive Level: Knowledge REF: p. 4 $r $r $ r $r
OBJ: 3NAT: NCLEX Client Needs Category: Physiological Inte
$r $r $r $r $r $r $r $r
grity
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
$ r $r $r $r $ r $r $r $r
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
$r $r $r $r $r $r $r $r $r $r $r $r $r
a. Drug Facts and Comparisons $r $r $r
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Editi
$r $r $r $r $r $r $r $r $r 3
on
b. Drug Interaction Facts $r $r
c. Handbook on Injectable Drugs $r $r $r
d. Martindale—The Complete Drug Reference $r $r $r
ANS: A $r
Drug Facts and Comparisons contains drug monographs that describe all drugs in at
$r $r $r $r $r $r $r $r $r $r $r $r $r
herapeutic class. Monographs are formatted as tables to allow comparison of similarp
$r $r $r $r $r $r $r $r $r $r $r r
$
roducts, brand names, manufacturers, cost indices, and available dosage forms Onlin
$r $r $r $r $r $r $r $r $r $r
e version is available.
$r $r $r
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 $r $r $ r $r $r $r
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
$r$r$ r $ r $r $r $r $r $r
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
$ r $r $r $r $ r $r $r $r $r $r $r
4. Which drug reference contains monographs about virtually every single-
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entity drug availablein the United States and describes therapeutic uses of drugs, including
$r $r $r $r $r $r $r $r $r $r $r $r $r $r
approved and unapproved uses? $r $r $r
a. Martindale: The Complete Drug Reference $r $r $r $r
b. AHFS Drug Information $r $r
c. Drug Reference $r
d. Drug Facts and Comparisons $r $r $r
ANS: B $r
AHFS Drug Information contains monographs about virtually every single-
$r $r $r $r $r $r $r $r
entity drug available in the United States and describes therapeutic uses of drugs, including ap
$r $r $r $r $r $r $r $r $r $r $r $r $r $r
proved andunapproved uses. $r $r $r
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 $r $r $ r $r $r $r
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
$r$r$ r $ r $r $r $r $r $r
TOP: Nursing Process Step: Planning
$ r CON: Safety | Patient Education | Clinical Judgment
$r $r $r $ r $r $r $r $r $r $r
5. Which online drug reference makes available to healthcare providers and the public a sta
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ndard, comprehensive, up-to-date look up and downloadable resource about medicines?
$r $r $r $r $r $r $r $r $r
a. American Drug Index $r $r
b. American Hospital Formulary $r $r
c. DailyMed
d. Drug Reference $r
ANS: C $r
DailyMed makes available to healthcare providers and the public a standard, comprehensive,
$r $r $r $r $r $r $r $r $r $r $r r
$
up-to-
date look up and downloadable resource about medicines. The American Drug Index isnot ap
$r $r $r $r $r $r $r $r $r $r $r $r r
$ $r
propriate for patient use. The American Hospital Formulary is not appropriate for patient u
$r $r $r $r $r $r $r $r $r $r $r $r $r
se. The drug reference is not appropriate for patient use.
$r $r $r $r $r $r $r $r $r
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 $r $r $ r $r $r $r $r
OBJ: 3NAT: NCLEX Client Needs Category: Physiological Inte
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grity
TOP: Nursing Process Step: Implementation
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CON: Safety | Patient Education | Clinical Judgment
$ r $r $r $r $r $r $r
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
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a. Federal Food, Drug, and Cosmetic Act (1938) $r $r $r $r $r $r
b. Durham Humphrey Amendment (1952) $r $r $r
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Editi
$r $r $r $r $r $r $r $r $r 4
on
c. Controlled Substances Act (1970) $r $r $r
d. Kefauver Harris Drug Amendment (1962) $r $r $r $r
ANS: A $r
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the saf
$r $r $r $r $r $r $r $r $r $r $r $r $r $r $r
ety of all drugs before marketing. Later amendments and acts helped tighten FDA control an
$r $r $r $r $r $r $r $r $r $r $r $r $r $r
d ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that ca
$r $r $r $r $r $r $r $r $r $r $r $r $r $r
nnot be used safely without medical supervision and restricts their sale to prescription by a li
$r $r $r $r $r $r $r $r $r $r $r $r $r $r $r
censed practitioner. The Controlled Substances Act addresses only controlled substances andt
$r $r $r $r $r $r $r $r $r $r r
$
heir categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater
$r $r $r $r $r $r $r $r $r $r $r r
$
drug safety. Drug manufacturers are required to prove to the FDA the effectiveness of their
$r $r $r $r $r $r $r $r $r $r $r $r $r $r $r
products before marketing them. $r $r $r
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 $r $r $r $r $r $r
OBJ: 5 $ r
NAT: NCLEX Client Needs Category: Physiological Integrit $r $r $r $r $r $r
yTOP: Nursing Process Step: Assessment
r
$ $r $r $r $r
CON: Safety | Patient Education | Evidence | Health Care Law
$ r $r $r $r $r $r $r $r $r $r
7. Which classification does meperidine (Demerol) fall under?
$r $r $r $r $r $r
a. I
b. II
c. III
d. IV
ANS: B $r
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead t
$r $r $r $r $r $r $r $r $r $r $r $r $r $r $r $r $r
osevere psychological and physical dependence. Schedule I drugs have high potential for abus
r
$ $r $r $r $r $r $r $r $r $r $r $r $r
eand no recognized medical use. Schedule III drugs have some potential for abuse. Use may
r
$ $r $r $r $r $r $r $r $r $r $r $r $r $r $r
lead to low to moderate physical dependence or high psychological dependence. Schedule I
$r $r $r $r $r $r $r $r $r $r $r $r $r
Vdrugs have low potential for abuse. Use may lead to limited physical or psychological dep
r
$ $r $r $r $r $r $r $r $r $r $r $r $r $r $r
endence.
DIF: Cognitive Level: Knowledge REF: p. 10 $r $r $ r $r
OBJ: 2NAT: NCLEX Client Needs Category: Safe, Effective Car $r $r $r $r $r $r $r $r $r
e Environment
$r
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
$ r $r $r $r $ r $r $r $r $r $r
8. Which action would the FDA take to expedite drug development and approval for an outbreak
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$
of smallpox?
$r
a. List smallpox as a health orphan disease.
$r $r $r $r $r $r
b. Omit the preclinical research phase. $r $r $r $r
c. Extend the clinical research phase. $r $r $r $r
d. Fast track the investigational drug. $r $r $r $r
ANS: D $r
Once the Investigational New Drug Application has been approved, the drug can receive hig
$r $r $r $r $r $r $r $r $r $r $r $r $r
hest priority within the agency, which is called fast tracking. A smallpox outbreak would be
$r $r $r $r $r $r $r $r $r $r $r $r $r $r
come a priority concern in the world. Orphan diseases are not researched in a priority manne
$r $r $r $r $r $r $r $r $r $r $r $r $r $r $r
r. Preclinical research is not omitted. Extending any phase of the research would meana long
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$
er time to develop a vaccine. The FDA must ensure that all phases of the preclinical andclinica
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$
l research phase have been completed in a safe manner.
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DIF: Cognitive Level: Knowledge $r $r REF: p. 7 $r$r$r $r OBJ: 5 $r
