Test Bank - Abrams’ Clinical Drug Therapy: Rationales for Nursing Practice, 13th Edition (Frandsen, 2025), 9781975222321, Chapter 1-61 All Chapters

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Chapter 1, The Foundation of Pharmacology: Quality and Safety
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1. A woman diagnosed with obsessive–
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compulsive disorder has been prescribed oral paroxetine hydrochloride. What is
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the expected effect for this prescription?
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A. Curative effect on symptoms $v $v $v


B. Systemic effect on symptoms $v $v $v


C. Local effect on symptoms $v $v $v


D. Parenteral effect on symptoms $v $v $v




ANS: B $ v


Rationale: Drugs that produce systemic effects are taken into the body, circulated through
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the bloodstream to their sites of action in various body tissues, and eventually eliminated
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from the body. Curative agents are given to cure a disease process. In this case, paroxeti
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ne hydrochloride will control the symptoms but not cure the disorder. Drugs with local eff
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ects, such as sunscreen and local anesthetics, act mainly at the site of application. Paroxet
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ine hydrochloride is not administered parenterally. Parenteral agents are administered sub
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cutaneously, intramuscularly, or intravenously. $v $v $v




PTS: 1 REF: p. 3, Introduction OBJ: 1 $v $v


NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand NOT: Multiple Choice
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2. A client has been prescribed an antibiotic. This medication is a naturally occurring
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substance that has been cheG
mRicA
alDlyEm
SoBdOifOieSd.TWhaOt Mi s another name for this type o
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f medication?
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A. Synthetic drug
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B. Semisynthetic drug $v
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C. Biotechnology drug $v
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D. Prototype drug $v
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ANS: B
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Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
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that have been chemically modified. Synthetic drugs are more standardized in their chemic
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al characteristics, more consistent in their effects, and less likely to produce allergic react
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ions. Biotechnology drugs involve manipulating DNA and RNA and recombining genes i
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nto hybrid molecules that can be inserted into living organisms. Prototype drugs are the f
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irst drug of a particular group to be developed.
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PTS: 1 REF: p. 3, Drug Sources OBJ: 1 $v $v $v


NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP:
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
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3. Which classification applies to morphine?
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A. Central nervous system depressant $v $v $v


B. Central nervous system stimulant $v $v $v





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