101 define
allergy and allergens
Allergy > -
the response of the body's immune system to a substance that is otherwise harmless most allergies are type 1
hypersensitivity
Allergen > substance that causes this response (immune response) reactions (IgE mediated
-
LO2 Describe the main steps involved in the development of allergy
Development of allergy >
-
type I
hypersensitivity reaction (IgE mediated
1 sensitization >
- no
symptoms
·
first exposure to an allergen ·
plasma B cells produce IgE antibodies ·
IgE antibodies attack to the cell membrane
specific to the allergen of most cells and basophils
&
.
2 Allergic reaction
·
re-exposure to same allergen allergen attaches to the IgE present o n most cell/basophils secrete
the sensitised mast cells/basophils inflammatory mediators
3
-
histamine
symptoms
- leukotrienes
-
prostaglanding
histamine is one of the
afterbinding major inflammatory mediator
conteainflammatory
-
me
that exist in these granules
and
produced
new be and is released in
allergy
will
mediators
allergy and allergens
Allergy > -
the response of the body's immune system to a substance that is otherwise harmless most allergies are type 1
hypersensitivity
Allergen > substance that causes this response (immune response) reactions (IgE mediated
-
LO2 Describe the main steps involved in the development of allergy
Development of allergy >
-
type I
hypersensitivity reaction (IgE mediated
1 sensitization >
- no
symptoms
·
first exposure to an allergen ·
plasma B cells produce IgE antibodies ·
IgE antibodies attack to the cell membrane
specific to the allergen of most cells and basophils
&
.
2 Allergic reaction
·
re-exposure to same allergen allergen attaches to the IgE present o n most cell/basophils secrete
the sensitised mast cells/basophils inflammatory mediators
3
-
histamine
symptoms
- leukotrienes
-
prostaglanding
histamine is one of the
afterbinding major inflammatory mediator
conteainflammatory
-
me
that exist in these granules
and
produced
new be and is released in
allergy
will
mediators
