Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Covered
PART 1: Foundations of Clinical Medicine
PART 2: Cardinal Symptoms & Clinical Presentations
PART 3: Clinical Pharmacology
PART 4: Oncology & Hematology
PART 5: Infectious Diseases
PART 6: Cardiovascular Disorders
PART 7: Respiratory Disorders
PART 8: Critical Care Medicine
PART 9: Kidney & Urinary Tract Disorders
PART 10: Gastrointestinal & Hepatobiliary Disorders
,PART 11: Immune-Mediated & Rheumatologic Disorders
PART 12: Endocrinology & Metabolism
PART 13: Neurologic & Psychiatric Disorders
PART 14: Toxicology & Environmental Injury
PART 15: Environmental & Occupational Medicine
PART 16: Genetics, Precision & Systems Medicine
PART 17–20: Special & Emerging Topics
1. A 68-year-old man presents with new-onset fatigue, weight
loss, and progressive shortness of breath on exertion. As
part of “the practice of medicine,” which initial nursing
action most directly supports accurate clinical decision-
making?
A. Obtain an extensive past psychiatric history.
B. Perform focused vital signs and pulse oximetry and
report abnormalities promptly.
C. Begin empiric broad-spectrum antibiotics.
D. Provide dietary counseling for weight loss.
Answer: B. Perform focused vital signs and pulse oximetry and
report abnormalities promptly.
Rationale: Early measurement of vitals and oxygenation
identifies immediate physiologic instability and guides timely
physician evaluation and diagnostics—core to safe clinical
practice and triage.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed. —
Chapter: The Practice of Medicine.
, 2. A nurse teaching a group of adults about primary
prevention should emphasize which behavior as the
highest-yield action to reduce chronic disease risk?
A. Annual full-body CT screening.
B. Healthy diet, regular physical activity, and tobacco
avoidance.
C. Daily multivitamin supplementation.
D. Routine use of herbal supplements.
Answer: B. Healthy diet, regular physical activity, and tobacco
avoidance.
Rationale: Lifestyle modification (diet, activity, smoking
cessation) is the most effective population-level preventive
measure for many chronic diseases; nursing education should
prioritize these evidence-based behaviors.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed. —
Chapter: Promoting Good Health.
3. A parent voices concern that vaccines cause serious long-
term harm. Which nursing response best addresses
vaccine hesitancy while supporting informed decision-
making?
A. State that no adverse events are possible and refuse
further discussion.
B. Acknowledge the concern, ask what they’ve heard,
provide clear, evidence-based information about risks and
, benefits, and offer resources.
C. Tell them vaccines are mandatory and ignore their
concerns.
D. Advise herbal alternatives instead of vaccines.
Answer: B. Acknowledge the concern, ask what they’ve heard,
provide clear, evidence-based information about risks and
benefits, and offer resources.
Rationale: Empathic listening, correction of misinformation,
and patient education support informed consent and increase
vaccination uptake—key nursing roles in addressing hesitancy.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed. —
Chapter: Vaccine Opposition and Hesitancy.
4. A hospitalized patient must decide between two cancer
treatments with differing risk/benefit profiles. Which
nursing action best supports shared decision-making?
A. Make the decision for the patient to speed care.
B. Provide neutral information about both options, assess
the patient’s values/goals, and notify the clinician to
include the patient’s preferences.
C. Only discuss the less expensive option.
D. Encourage the patient to defer to family without
exploring their preference.
Answer: B. Provide neutral information about both options,
assess the patient’s values/goals, and notify the clinician to
include the patient’s preferences.
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Covered
PART 1: Foundations of Clinical Medicine
PART 2: Cardinal Symptoms & Clinical Presentations
PART 3: Clinical Pharmacology
PART 4: Oncology & Hematology
PART 5: Infectious Diseases
PART 6: Cardiovascular Disorders
PART 7: Respiratory Disorders
PART 8: Critical Care Medicine
PART 9: Kidney & Urinary Tract Disorders
PART 10: Gastrointestinal & Hepatobiliary Disorders
,PART 11: Immune-Mediated & Rheumatologic Disorders
PART 12: Endocrinology & Metabolism
PART 13: Neurologic & Psychiatric Disorders
PART 14: Toxicology & Environmental Injury
PART 15: Environmental & Occupational Medicine
PART 16: Genetics, Precision & Systems Medicine
PART 17–20: Special & Emerging Topics
1. A 68-year-old man presents with new-onset fatigue, weight
loss, and progressive shortness of breath on exertion. As
part of “the practice of medicine,” which initial nursing
action most directly supports accurate clinical decision-
making?
A. Obtain an extensive past psychiatric history.
B. Perform focused vital signs and pulse oximetry and
report abnormalities promptly.
C. Begin empiric broad-spectrum antibiotics.
D. Provide dietary counseling for weight loss.
Answer: B. Perform focused vital signs and pulse oximetry and
report abnormalities promptly.
Rationale: Early measurement of vitals and oxygenation
identifies immediate physiologic instability and guides timely
physician evaluation and diagnostics—core to safe clinical
practice and triage.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed. —
Chapter: The Practice of Medicine.
, 2. A nurse teaching a group of adults about primary
prevention should emphasize which behavior as the
highest-yield action to reduce chronic disease risk?
A. Annual full-body CT screening.
B. Healthy diet, regular physical activity, and tobacco
avoidance.
C. Daily multivitamin supplementation.
D. Routine use of herbal supplements.
Answer: B. Healthy diet, regular physical activity, and tobacco
avoidance.
Rationale: Lifestyle modification (diet, activity, smoking
cessation) is the most effective population-level preventive
measure for many chronic diseases; nursing education should
prioritize these evidence-based behaviors.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed. —
Chapter: Promoting Good Health.
3. A parent voices concern that vaccines cause serious long-
term harm. Which nursing response best addresses
vaccine hesitancy while supporting informed decision-
making?
A. State that no adverse events are possible and refuse
further discussion.
B. Acknowledge the concern, ask what they’ve heard,
provide clear, evidence-based information about risks and
, benefits, and offer resources.
C. Tell them vaccines are mandatory and ignore their
concerns.
D. Advise herbal alternatives instead of vaccines.
Answer: B. Acknowledge the concern, ask what they’ve heard,
provide clear, evidence-based information about risks and
benefits, and offer resources.
Rationale: Empathic listening, correction of misinformation,
and patient education support informed consent and increase
vaccination uptake—key nursing roles in addressing hesitancy.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed. —
Chapter: Vaccine Opposition and Hesitancy.
4. A hospitalized patient must decide between two cancer
treatments with differing risk/benefit profiles. Which
nursing action best supports shared decision-making?
A. Make the decision for the patient to speed care.
B. Provide neutral information about both options, assess
the patient’s values/goals, and notify the clinician to
include the patient’s preferences.
C. Only discuss the less expensive option.
D. Encourage the patient to defer to family without
exploring their preference.
Answer: B. Provide neutral information about both options,
assess the patient’s values/goals, and notify the clinician to
include the patient’s preferences.
