Medical-Surgical Nursing MCQ Study Guide & Practice Test Bank (Fast Revision)

Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank




Covered

PART 1: Foundations of Clinical Medicine

PART 2: Cardinal Symptoms & Clinical Presentations

PART 3: Clinical Pharmacology

PART 4: Oncology & Hematology

PART 5: Infectious Diseases

PART 6: Cardiovascular Disorders

PART 7: Respiratory Disorders

PART 8: Critical Care Medicine

PART 9: Kidney & Urinary Tract Disorders

PART 10: Gastrointestinal & Hepatobiliary Disorders

,PART 11: Immune-Mediated & Rheumatologic Disorders

PART 12: Endocrinology & Metabolism

PART 13: Neurologic & Psychiatric Disorders

PART 14: Toxicology & Environmental Injury

PART 15: Environmental & Occupational Medicine

PART 16: Genetics, Precision & Systems Medicine

PART 17–20: Special & Emerging Topics




1. The Practice of Medicine
1. Which principle best characterizes modern clinical medicine
as described in Harrison’s?
A. Disease-centered decision-making
B. Physician autonomy over patient values
C. Integration of evidence, clinical expertise, and patient values
D. Reliance on technological diagnostics over history
Correct Answer: C
Rationale: Harrison’s emphasizes evidence-based medicine
integrated with clinician expertise and patient preferences.
Citation: Harrison’s 22nd ed., Ch. 1 The Practice of Medicine


2. Promoting Good Health
2. A nurse counseling a patient on health promotion should
prioritize which intervention with the greatest population-level
impact?

,A. Genetic screening
B. Lifestyle modification
C. Early pharmacologic therapy
D. Advanced imaging
Correct Answer: B
Rationale: Behavioral and lifestyle factors (diet, exercise,
tobacco avoidance) have the largest effect on population
health.
Citation: Harrison’s 22nd ed., Ch. 2 Promoting Good Health


3. Vaccine Opposition and Hesitancy
3. What is the most effective clinician strategy for addressing
vaccine hesitancy?
A. Presenting statistical risk data alone
B. Dismissing patient concerns
C. Building trust through respectful dialogue
D. Deferring discussion indefinitely
Correct Answer: C
Rationale: Harrison’s highlights trust, empathy, and clear
communication as central to overcoming hesitancy.
Citation: Harrison’s 22nd ed., Ch. 3 Vaccine Opposition and
Hesitancy


4. Decision-Making in Clinical Medicine

, 4. Shared decision-making is MOST appropriate when:
A. Evidence strongly favors one option
B. The patient lacks decisional capacity
C. Multiple reasonable options exist
D. Emergency intervention is required
Correct Answer: C
Rationale: Shared decision-making is indicated when benefits
and risks vary by patient values.
Citation: Harrison’s 22nd ed., Ch. 4 Decision-Making in Clinical
Medicine


5. Precision Medicine and Clinical Care
5. Precision medicine primarily aims to:
A. Replace clinical judgment
B. Tailor care based on individual variability
C. Standardize treatment protocols
D. Reduce the need for diagnostics
Correct Answer: B
Rationale: Precision medicine integrates genetic,
environmental, and lifestyle factors to individualize care.
Citation: Harrison’s 22nd ed., Ch. 5 Precision Medicine and
Clinical Care


6. Screening and Prevention of Disease