Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Covered
PART 1: Foundations of Clinical Medicine
PART 2: Cardinal Symptoms & Clinical Presentations
PART 3: Clinical Pharmacology
PART 4: Oncology & Hematology
PART 5: Infectious Diseases
PART 6: Cardiovascular Disorders
PART 7: Respiratory Disorders
PART 8: Critical Care Medicine
PART 9: Kidney & Urinary Tract Disorders
PART 10: Gastrointestinal & Hepatobiliary Disorders
,PART 11: Immune-Mediated & Rheumatologic Disorders
PART 12: Endocrinology & Metabolism
PART 13: Neurologic & Psychiatric Disorders
PART 14: Toxicology & Environmental Injury
PART 15: Environmental & Occupational Medicine
PART 16: Genetics, Precision & Systems Medicine
PART 17–20: Special & Emerging Topics
1. The Practice of Medicine
1. Which principle best defines evidence-based medical
practice?
A. Reliance on expert opinion
B. Use of the most recent technology
C. Integration of clinical expertise with best available evidence
D. Standardized treatment regardless of patient context
Correct Answer: C
Rationale: Evidence-based medicine integrates clinician
expertise, patient values, and the best research evidence.
Citation: Harrison’s 22nd ed., Ch. 1 – The Practice of Medicine
2. Promoting Good Health
2. Which intervention has the greatest population-level impact
on reducing morbidity?
A. Tertiary care services
,B. Lifestyle modification
C. Genetic screening
D. Hospital-based treatment
Correct Answer: B
Rationale: Behavioral and lifestyle interventions significantly
reduce chronic disease burden at the population level.
Citation: Harrison’s 22nd ed., Ch. 2 – Promoting Good Health
3. Vaccine Opposition and Hesitancy
3. The most effective nursing response to vaccine hesitancy is:
A. Presenting statistical data only
B. Dismissing concerns as misinformation
C. Engaging in respectful, empathetic dialogue
D. Mandating vaccination
Correct Answer: C
Rationale: Trust-building and empathetic communication
improve vaccine acceptance.
Citation: Harrison’s 22nd ed., Ch. 3 – Vaccine Opposition and
Hesitancy
4. Decision-Making in Clinical Medicine
4. Shared decision-making primarily emphasizes:
A. Physician authority
B. Patient autonomy and values
, C. Cost containment
D. Clinical algorithms
Correct Answer: B
Rationale: Clinical decisions should align with patient
preferences and informed consent.
Citation: Harrison’s 22nd ed., Ch. 4 – Decision-Making in Clinical
Medicine
5. Precision Medicine and Clinical Care
5. Precision medicine primarily aims to:
A. Replace clinical judgment
B. Apply uniform treatments
C. Tailor care using genetic and molecular data
D. Reduce healthcare costs
Correct Answer: C
Rationale: Precision medicine customizes prevention and
treatment based on individual variability.
Citation: Harrison’s 22nd ed., Ch. 5 – Precision Medicine and
Clinical Care
6. Screening and Prevention of Disease
6. Which factor is MOST critical when evaluating a screening
test?
A. Cost
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Covered
PART 1: Foundations of Clinical Medicine
PART 2: Cardinal Symptoms & Clinical Presentations
PART 3: Clinical Pharmacology
PART 4: Oncology & Hematology
PART 5: Infectious Diseases
PART 6: Cardiovascular Disorders
PART 7: Respiratory Disorders
PART 8: Critical Care Medicine
PART 9: Kidney & Urinary Tract Disorders
PART 10: Gastrointestinal & Hepatobiliary Disorders
,PART 11: Immune-Mediated & Rheumatologic Disorders
PART 12: Endocrinology & Metabolism
PART 13: Neurologic & Psychiatric Disorders
PART 14: Toxicology & Environmental Injury
PART 15: Environmental & Occupational Medicine
PART 16: Genetics, Precision & Systems Medicine
PART 17–20: Special & Emerging Topics
1. The Practice of Medicine
1. Which principle best defines evidence-based medical
practice?
A. Reliance on expert opinion
B. Use of the most recent technology
C. Integration of clinical expertise with best available evidence
D. Standardized treatment regardless of patient context
Correct Answer: C
Rationale: Evidence-based medicine integrates clinician
expertise, patient values, and the best research evidence.
Citation: Harrison’s 22nd ed., Ch. 1 – The Practice of Medicine
2. Promoting Good Health
2. Which intervention has the greatest population-level impact
on reducing morbidity?
A. Tertiary care services
,B. Lifestyle modification
C. Genetic screening
D. Hospital-based treatment
Correct Answer: B
Rationale: Behavioral and lifestyle interventions significantly
reduce chronic disease burden at the population level.
Citation: Harrison’s 22nd ed., Ch. 2 – Promoting Good Health
3. Vaccine Opposition and Hesitancy
3. The most effective nursing response to vaccine hesitancy is:
A. Presenting statistical data only
B. Dismissing concerns as misinformation
C. Engaging in respectful, empathetic dialogue
D. Mandating vaccination
Correct Answer: C
Rationale: Trust-building and empathetic communication
improve vaccine acceptance.
Citation: Harrison’s 22nd ed., Ch. 3 – Vaccine Opposition and
Hesitancy
4. Decision-Making in Clinical Medicine
4. Shared decision-making primarily emphasizes:
A. Physician authority
B. Patient autonomy and values
, C. Cost containment
D. Clinical algorithms
Correct Answer: B
Rationale: Clinical decisions should align with patient
preferences and informed consent.
Citation: Harrison’s 22nd ed., Ch. 4 – Decision-Making in Clinical
Medicine
5. Precision Medicine and Clinical Care
5. Precision medicine primarily aims to:
A. Replace clinical judgment
B. Apply uniform treatments
C. Tailor care using genetic and molecular data
D. Reduce healthcare costs
Correct Answer: C
Rationale: Precision medicine customizes prevention and
treatment based on individual variability.
Citation: Harrison’s 22nd ed., Ch. 5 – Precision Medicine and
Clinical Care
6. Screening and Prevention of Disease
6. Which factor is MOST critical when evaluating a screening
test?
A. Cost
