PMT
Please check the examination details below before entering your candidate information
Candidate surname Other names
Pearson Edexcel Centre Number Candidate Number
International
Advanced Level
Wednesday 13 January 2021
Afternoon (Time: 1 hour 45 minutes) Paper Reference WBI14/01
Biology
International Advanced Level
Unit 4 : Energy, Environment, Microbiology and
Immunity
You must have: Total Marks
Scientific calculator, ruler, HB pencil
Instructions
• Use black ink or ball-point pen.
• centrethe
Fill in boxes at the top of this page with your name,
number and candidate number.
• Answer all questions.
• Answer the questions in the spaces provided
– there may be more space than you need.
• Show all your working in calculations and include units where appropriate.
Information
• The total mark for this paper is 90.
• – usemarks
The for each question are shown in brackets
this as a guide as to how much time to spend on each question.
• toIn questions marked with an asterisk (*), marks will be awarded for your ability
structure your answer logically showing how the points that you make are
related or follow on from each other where appropriate.
Advice
• Read each question carefully before you start to answer it.
• Try to answer every question.
• Check your answers if you have time at the end.
Turn over
P66156A
©2021 Pearson Education Ltd.
1/1/1/1/1
*P66156A0132*
, PMT
Answer ALL questions.
Write your answers in the spaces provided.
Some questions must be answered with a cross in a box . If you change your mind about an
answer, put a line through the box and then mark your new answer with a cross .
1 Inflammation is involved in the non-specific response of the body to infection and
injury.
(a) (i) Complete the diagram to show the four characteristics of inflammation.
(2)
swelling
... .......... .......... ........... .......... .......... ........ ................. ..............
Characteristics of
inflammation
. .. ... ... .. ... .. ... .. ... .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....... .......... .......... .......... .......... .......... ..... .................... ...........
(ii) Inflammation occurs following a cut to the skin.
Describe the role of two of these characteristics of inflammation in response
to a cut to the skin.
(2)
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
2
*P66156A0232*
, PMT
(b) Anti-inflammatory drugs reduce inflammation.
Turmeric is a spice that is added to food.
Curcumin is a chemical in turmeric that has been shown to reduce inflammation.
(i) The graph shows the effect of treating inflammation with curcumin extract
and an anti-inflammatory drug, drug A.
inflammation with
no treatment
Inflammation
Key
drug A
curcumin extract
1 2 3 4 5 6
Days after treatment
Compare and contrast the effect of treating inflammation with curcumin
extract and with drug A.
(3)
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... ..................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ......... .............
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
3
*P66156A0332* Turn over
, PMT
(ii) Many treatments use 1 g curcumin extract.
A sample of turmeric contains 3 % curcumin.
Which is the mass of turmeric for one treatment?
(1)
A 0.03 g
B 3.33 g
C 33.3 g
D 33.4 g
(Total for Question 1 = 8 marks)
4
*P66156A0432*
Please check the examination details below before entering your candidate information
Candidate surname Other names
Pearson Edexcel Centre Number Candidate Number
International
Advanced Level
Wednesday 13 January 2021
Afternoon (Time: 1 hour 45 minutes) Paper Reference WBI14/01
Biology
International Advanced Level
Unit 4 : Energy, Environment, Microbiology and
Immunity
You must have: Total Marks
Scientific calculator, ruler, HB pencil
Instructions
• Use black ink or ball-point pen.
• centrethe
Fill in boxes at the top of this page with your name,
number and candidate number.
• Answer all questions.
• Answer the questions in the spaces provided
– there may be more space than you need.
• Show all your working in calculations and include units where appropriate.
Information
• The total mark for this paper is 90.
• – usemarks
The for each question are shown in brackets
this as a guide as to how much time to spend on each question.
• toIn questions marked with an asterisk (*), marks will be awarded for your ability
structure your answer logically showing how the points that you make are
related or follow on from each other where appropriate.
Advice
• Read each question carefully before you start to answer it.
• Try to answer every question.
• Check your answers if you have time at the end.
Turn over
P66156A
©2021 Pearson Education Ltd.
1/1/1/1/1
*P66156A0132*
, PMT
Answer ALL questions.
Write your answers in the spaces provided.
Some questions must be answered with a cross in a box . If you change your mind about an
answer, put a line through the box and then mark your new answer with a cross .
1 Inflammation is involved in the non-specific response of the body to infection and
injury.
(a) (i) Complete the diagram to show the four characteristics of inflammation.
(2)
swelling
... .......... .......... ........... .......... .......... ........ ................. ..............
Characteristics of
inflammation
. .. ... ... .. ... .. ... .. ... .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....... .......... .......... .......... .......... .......... ..... .................... ...........
(ii) Inflammation occurs following a cut to the skin.
Describe the role of two of these characteristics of inflammation in response
to a cut to the skin.
(2)
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
2
*P66156A0232*
, PMT
(b) Anti-inflammatory drugs reduce inflammation.
Turmeric is a spice that is added to food.
Curcumin is a chemical in turmeric that has been shown to reduce inflammation.
(i) The graph shows the effect of treating inflammation with curcumin extract
and an anti-inflammatory drug, drug A.
inflammation with
no treatment
Inflammation
Key
drug A
curcumin extract
1 2 3 4 5 6
Days after treatment
Compare and contrast the effect of treating inflammation with curcumin
extract and with drug A.
(3)
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... ..................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ......... .............
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
.. .. ... .. ... .. ... .. ... .. ... ... .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .... .......... .. ........ .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ...... .............. ..... .................
3
*P66156A0332* Turn over
, PMT
(ii) Many treatments use 1 g curcumin extract.
A sample of turmeric contains 3 % curcumin.
Which is the mass of turmeric for one treatment?
(1)
A 0.03 g
B 3.33 g
C 33.3 g
D 33.4 g
(Total for Question 1 = 8 marks)
4
*P66156A0432*
