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CDE Exam Prep – Medications Questions and answers Updated 2026

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CDE Exam Prep – Medications
Questions and answers Updated
2026
SulfonylureasB-
BAnswerLowerBbgBbyBcausingBtheBpancreasBtoBreleaseBmoreBinsulinBA1cBdecreaseBwithBmon
otherapy:B1-2%

BiguanidesB-
BAnswerReduceBhowBmuchBglucoseBtheBliverBproduces;BincreaseBperipheralBinsulinBsensitivity.
BA1cBdecreaseBwithBmonotherapy:B1-2%

ThiazolidinedionesB-
BAnswerImproveBtheBwayBinsulinBworksBinBtheBbodyBbyBallowingBmoreBglucoseBtoBenterBmu
scles,Bfat,BandBtheBliver;BaboutB12-
16BweeksBforBmaximumBeffect.BA1cBdecreaseBwithBmonotherapy:B0.5-1.4%

Alpha-glucosidaseBinhibitorsB-
BAnswerLowerBbgBbyBdelayingBtheBbreakdownBofBcarbohydratesBandBreducingBglucoseBabsorp
tionBinBtheBsmallBintestine.BTheyBalsoBblockBcertainBenzymesBinBorderBtoBslowBdownBtheBdig
estionBofBsomeBstarches;BtreatBlowsBwithBmilkBorBglucoseBtabs;BA1cBdecreaseBwithBmonothe
rapy:B0.5-0.8%

MeglitinideB-
BAnswershortBactingBinsulinBsecretagogues;BstimulateBinsulinBreleaseBfromBpancreasBA1cBdecr
easeBwithBmonotherapy:B0.5-1.5%

DPP-4BinhibitorsB-
BAnswerHelpBtheBpancreasBtoBreleaseBmoreBinsulinBafterBmeals.BTheyBalsoBlowerBtheBamoun
tBofBglucoseBreleasedBbyBtheBliver.BA1cBdecreaseBwithBmonotherapy:B0.5-0.8%

SGLT2BinhibitorsB-
BAnswerWorkBonBtheBkidneysBtoBremoveBextraBsugarBfromBtheBbody;BA1cBdecreaseBwithBmo
notherapy:B0.8-1%

BileBacidBsequestrantB-BAnswerLowerBcholesterolBandBbgBlevelsBinBptsBwhoBhaveBdiabetes

, GLP-1BanalogsB-
BAnswerincreaseBinsulinBsecretion,BreduceBglucoseBreleaseBfromBliverBafterBmeals,BdelayBfood
BemptyingBfromBstomachBandBpromoteBsatiety

DopamineBagonistB-
BAnswerlowersBtheBamountBofBglucoseBreleasedBbyBtheBliver;BA1cBdecreaseBwithBmonotherap
y:B0.1-0.4%

MetforminBclass,BaffectBonBwt,BaffectBonBweightB-BAnswerBiguanide;BwtBneutral

Glimepiride,BGlyburide,BGlipizideBclass,BaffectBonBwtB-BAnswerSulfonylureas;BwtBgain

Pioglitazone,BRosiglitozoneBclass,BaffectBonBwtB-BAnswerThiazolidinedionesB(TZDs);BwtBgain

Acarbose,BMiglitolBclass,BaffectBonBweightB-BAnswerAlpha-glucosidaseBinhibitors;BwtBneutral

Repaglinide,BNateglinideBclass,BaffectBonBweightB-BAnswerMeglitinide;BwtBneutral

Sitagliptin,BSaxagliptin,BLinagliptin,BAlogliptinBclass,BaffectBonBweightB-BAnswerDPP-
4BInhibitors;BwtBneutral

Canagliflozin,BDapagliflozin,BEmpagliflozinBclass,BaffectBonBweightB-
BAnswerSGLT2BInhibitors;BwtBloss

ColesevelamBclassB-BAnswerBileBacidBsequestrant

Exenatide,BLiraglutide,BAlbiglutide,BDulaglutide,Bclass,BaffectBonBweightB-BAnswerGLP-
1BanalogsB,BwtBloss

BromocriptineBclass,BaffectBonBweightB-BAnswerDopamineBagonist;BwtBneutral

RapidBactingBinsulinB-
BAnswerInsulinBglulisineB(Apidra),BInsulinBlisproB(Humalog),BInsulinBaspartB(Novolog),BTechnosp
hereBinsulinBinhalationBsystemB(Afrezza)

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