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HESI A2 Anatomy & Physiology Study Guide

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Prepare for the HESI A2 Anatomy & Physiology exam with this comprehensive study guide. Covering key concepts in human anatomy and physiology, this resource includes essential information on organ systems, tissues, cells, and physiological processes, along with practice questions and answers. This study guide provides a thorough review of the anatomy and physiology topics crucial for success on the HESI A2 exam.

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HESI A2 ANATOMY AND PHYSIOLOGY 2025_2026 STUDY QUESTIONS
WITH CORRECT ANSWERS
The specialized junction from which
nerve impulses pass from one neu-
Synapse
ron to the next is called a
.
Which type of bone has a diaphysis and
Long bone
two epiphyses?
Which of the following correctly de-
It stimulates the production of testos-
scribes the function of luteinizing hor-
terone in males
mone?
Which of the following statements is in- It stimulates ovulation ( This is the
correct about estrogen? luteinizing hormone job)
What is the role of calcium in muscle Calcium binds to troponin and leads to
contraction? the uncovering of the active site of actin.
Which structure controls the activity of
Hypothalmus
the endocrine system?
The left atrium receives blood from the
Pulmonary vein
.
Which is the most abundant nervous tis-
Neuroglia
sue?
The tibia is to the femur. Distal
Which of the following organelles would
you expect to find an abundance of in Lysosomes
leukocytes?
A patient with a lower than normal
amount of thrombocytes could be at risk extensive bleeding
of .
A sprain occurs when which of the follow-
Ligament
ing structures is stretched or torn?
Which of the following glands secrete
Ceruminous
earwax?
What is the function of endocrine They secrete hormones directly into the
glands? blood.




, HESI A2 ANATOMY AND PHYSIOLOGY 2025_2026 STUDY QUESTIONS
WITH CORRECT ANSWERS
Which of the following occurs when the Heart rate increases
sympathetic nervous system is stimulat- Pupils dilate
ed? Digestion slows down
Which bones form via intramembranous The flat bones of the skull, the mandible,
ossification? and clavicles
The carpals articulate with the distal
Radius and ulna
ends of which two bones?
Which of the following best describes the Lets blood flow from the left atrium to the
function of the mitral valve? left ventricle
Which type of connection do ligaments
Bone to Bone
create?
Which of the four chambers of the heart
Left ventricle
has the thickest muscular wall?
Which important minerals are stored
Calcium and phosphorous
within the skeletal system?
Which type of tissue is most widely dis-
Connective tissue
tributed throughout the body?
In which of the following reproductive
structures does the fertilization of an Fallopian tube
ovum occur?
Which of the following structures is part
Pharynx
of the upper respiratory system?
Eccrine glands secrete a watery sub-
stance onto the surface of the skin
Evaporation
to maintain temperature homeostasis
through which process?
What, in addition to adenosine triphos-
phate, must be present for a muscle to Calcium
contract?
Mitosis occurs in which layer of the skin? Stratum germinativum
A patient reveals to you that they were re-
cently involved in a car accident that they
vomer is a thin, vertical bone in the nose.
believe resulted in a deviated septum.
Which of the following bones may have


, HESI A2 ANATOMY AND PHYSIOLOGY 2025_2026 STUDY QUESTIONS
WITH CORRECT ANSWERS
been injured in the accident, resulting in
the deviated septum?
Which of the following describes cellular
It is an oxidative catabolic activity
respiration?
Which structure in the epidermis is re-
sponsible for cooling the body to main- Eccrine glands ( produces sweat )
tain temperature homeostasis?
Which system coordinates and regulates
processes within the body through the Endocrine system
use of hormones?
What is one of the functions of the hypo-
Regulate body temperature
thalamus?
Proximal Convoluted Tubule - Loop of
Which of the following is the correct se-
Henle - Distal Convoluted Tubule - Col-
quence of transport of filtrate from the
lecting Duct - Minor Calyx - Major Calyx
nephrons to the renal pelvis?
- Renal Pelvis
Which of the following features of veins
Veins have thinner, more compliant ves-
results in the venous system operating at
sel walls than arteries.
lower pressures than the arterial side?
Which blood vessel delivers blood direct-
Vena cava
ly into the right atrium?
Which of the following terms describes
the process of forming new red blood Erythropoiesis
cells?
Which of the following salivary glands
primarily contributes to the production Submandibular glands
and secretion of saliva?
Which of the following gets absorbed di-
Amino acids
rectly into the blood?
Which glands release an oily secretion
through the hair follicles that lubricates Sebaceous glands
the skin and prevents drying?
Which of the following makes up the
Plasma
largest component of whole blood?

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