ONS/ONCC COMPREHENSIVE TEST
SCRIPT 2026 QUESTIONS WITH
SOLUTIONS 100% CORRECT.
⩥ Non-DNA-binding solutions remain in the local area of the
extravasation, which improves the possibility of drug deactivation.
DNA-binding agents attach to DNA nucleic acids, causing the antagonist
to be ingested cellularly, leading to progressive tissue destruction.
Answer: A further classification of an antineoplastic agent's potential to
cause damage is whether its mechanism of action includes DNA binding.
⩥ Bendamustinea
Dactinomycin
Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
Mechlorethamine
Mitomycin. Answer: DNA Binding Irritants
⩥ Amsacrine
,Paclitaxel
Vinblastine
Vincristine
Vindesine
Vinorelbine. Answer: DNA Nonbinding vessicants
⩥ Sodium thiosulfate
Inject 2 ml of sodium thiosulfate for each milligram of
mechlorethamine extravasated.
Inject subcutaneously into extravasation site using a 25
gauge or smaller needle (change needle with each injection).
Monitor extravasation site according to the institution's
policies and procedures.. Answer: Extravasciation Alkylating /
Mechlorethamine tx
⩥ Apply warm compresses.
Dexamethasone
8 mg twice daily
for 14 days. Answer: Extravasciation Alkylating: Oxaliplatin
⩥ Totect
, Apply ice pack (remove 15
minutes prior to Totect
treatment).
Infusion should be initiated within six hours of extravasation.
Infused over 1-2 hours for three days in an area other
than the extravasation site
The dose recommended is based on the patients' body
surface area.
• Day 1: 1,000 mg/m2
• Day 2: 1,000 mg/m2
• Day 3: 500 mg/m. Answer: Extravasation Tx: Anthracyclines ---
Daunorubicin,
doxorubicin, epirubicin,
idarubicin
⩥ Hyaluronidase
Apply warm pack for
15-20 minutes four times
daily the next 24-48
SCRIPT 2026 QUESTIONS WITH
SOLUTIONS 100% CORRECT.
⩥ Non-DNA-binding solutions remain in the local area of the
extravasation, which improves the possibility of drug deactivation.
DNA-binding agents attach to DNA nucleic acids, causing the antagonist
to be ingested cellularly, leading to progressive tissue destruction.
Answer: A further classification of an antineoplastic agent's potential to
cause damage is whether its mechanism of action includes DNA binding.
⩥ Bendamustinea
Dactinomycin
Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
Mechlorethamine
Mitomycin. Answer: DNA Binding Irritants
⩥ Amsacrine
,Paclitaxel
Vinblastine
Vincristine
Vindesine
Vinorelbine. Answer: DNA Nonbinding vessicants
⩥ Sodium thiosulfate
Inject 2 ml of sodium thiosulfate for each milligram of
mechlorethamine extravasated.
Inject subcutaneously into extravasation site using a 25
gauge or smaller needle (change needle with each injection).
Monitor extravasation site according to the institution's
policies and procedures.. Answer: Extravasciation Alkylating /
Mechlorethamine tx
⩥ Apply warm compresses.
Dexamethasone
8 mg twice daily
for 14 days. Answer: Extravasciation Alkylating: Oxaliplatin
⩥ Totect
, Apply ice pack (remove 15
minutes prior to Totect
treatment).
Infusion should be initiated within six hours of extravasation.
Infused over 1-2 hours for three days in an area other
than the extravasation site
The dose recommended is based on the patients' body
surface area.
• Day 1: 1,000 mg/m2
• Day 2: 1,000 mg/m2
• Day 3: 500 mg/m. Answer: Extravasation Tx: Anthracyclines ---
Daunorubicin,
doxorubicin, epirubicin,
idarubicin
⩥ Hyaluronidase
Apply warm pack for
15-20 minutes four times
daily the next 24-48
