UST ABSN Pathopharmacology 1
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EXAM QUESTIONS WITH ANSWERS |\ |\ |\
A drug is any chemical that can affect living processes -
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CORRECT ANSWERS ✔✔How do you define the word drug?
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Pharmacology can be defined as the study of drugs and their |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
interaction with living things - CORRECT ANSWERS ✔✔Define
|\ |\ |\ |\ |\ |\ |\ |\
pharmacology
study of effect of drugs in man (as compared to animals or
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
comparative pharmacology - CORRECT ANSWERS ✔✔Define |\ |\ |\ |\ |\ |\
clinical pharmacology |\
also known as therapeutics, pharmacotherapeutics emphasizes
|\ |\ |\ |\ |\ |\
the disease state and its characteristics including therapy for and
|\ |\ |\ |\ |\ |\ |\ |\ |\
use of drugs in prevention and treatment of condition - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔what are pharmacotherapeutics?
|\ |\ |\ |\
Drugs used to destroy or eliminate pathogenic cells or organisms.
|\ |\ |\ |\ |\ |\ |\ |\ |\
The term is usually restricted to anti-infectives and cancer
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
chemotherapy. - CORRECT ANSWERS ✔✔what are |\ |\ |\ |\ |\ |\
chemotherapeutic agents? |\
Toxicology deals with the effects of drugs. Toxicity is measured
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
through the Therapeutic Index. - CORRECT ANSWERS ✔✔what is
|\ |\ |\ |\ |\ |\ |\ |\ |\
toxicology and how do we measure a drugs toxicity?
|\ |\ |\ |\ |\ |\ |\ |\
,therapeutic index is a ratio that measures toxicity. The ratio is
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
found by putting the dose *capable of killing 50% of animals
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
(LD50) over than required to acheive a beneficial effect in 50% of
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
animals (ED50).
|\ |\ |\
In clinical practice the THERAPEUTIC INDEX is described as the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
ratio of the dose that causes toxicity over the dose that provides
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
therapeutic effect. - CORRECT ANSWERS ✔✔What is the |\ |\ |\ |\ |\ |\ |\ |\
therapeutic index? |\
Tolerance is the hyporeactivity that occurring from chronic
|\ |\ |\ |\ |\ |\ |\ |\
exposure to a drug. Achievement of the same effects of the drug
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
requires larger and larger doses. - CORRECT ANSWERS ✔✔what is
|\ |\ |\ |\ |\ |\ |\ |\ |\
tolerance?
|\
Cross tolerance may happen when tolerance occurs across drugs
|\ |\ |\ |\ |\ |\ |\ |\ |\
of the same class or across drugs that have the same
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
pharmacological effects - CORRECT ANSWERS ✔✔What is cross |\ |\ |\ |\ |\ |\ |\ |\
tolerance and how does it occur? |\ |\ |\ |\ |\
Tolerance to opioids, barbiturates, and alcohol - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔what are some examples of neurological
|\ |\ |\ |\ |\ |\ |\
adaptation/ cellular tolerance to drugs? |\ |\ |\ |\
metabolic drug tolerance occurs when the body has an increased
|\ |\ |\ |\ |\ |\ |\ |\ |\
rate of elimination of the drug. - CORRECT ANSWERS ✔✔What is
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
metabolic drug tolerance? |\ |\
, enzyme induction which occurs when there is an increased
|\ |\ |\ |\ |\ |\ |\ |\ |\
activity of enzymes (the drug transport system) - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔what is the most common form of metabolic |\ |\ |\ |\ |\ |\ |\ |\ |\
tolerance?
pharmacodynamic processes determine the nature and intensity |\ |\ |\ |\ |\ |\ |\
of the response. It is essentially the effect of the drug ON the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
body.
EX: Target Organ, receptors, proteins, physiological effect etc. -
|\ |\ |\ |\ |\ |\ |\ |\ |\
CORRECT ANSWERS ✔✔What is pharmacodynamics? |\ |\ |\ |\
Pharmacokinetic processes determine how much of an admin- |\ |\ |\ |\ |\ |\ |\ |\
istered dose gets to its sites of action. There are four major
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
pharmacokinetic processes: (1) drug absorption, (2) drug |\ |\ |\ |\ |\ |\ |\
distribution, (3) drug metabolism, and (4) drug excretion. *These |\ |\ |\ |\ |\ |\ |\ |\ |\
processes can be thought of as the impact of the body on drugs*
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
- CORRECT ANSWERS ✔✔What is pharmacokinetics?
|\ |\ |\ |\ |\ |\
what are the four major pharmacokinetic processes?
|\ |\ |\ |\ |\ |\
Down regulation - CORRECT ANSWERS ✔✔what type of tolerance
|\ |\ |\ |\ |\ |\ |\ |\ |\
occurs when there is a decrease in the number, or decrease in
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
the sensitivity, of receptor sites?
|\ |\ |\ |\
betablockers - CORRECT ANSWERS ✔✔what kind of drugs block |\ |\ |\ |\ |\ |\ |\ |\ |\
receptors?
|\ |\ |\ |\
EXAM QUESTIONS WITH ANSWERS |\ |\ |\
A drug is any chemical that can affect living processes -
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
CORRECT ANSWERS ✔✔How do you define the word drug?
|\ |\ |\ |\ |\ |\ |\ |\
Pharmacology can be defined as the study of drugs and their |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
interaction with living things - CORRECT ANSWERS ✔✔Define
|\ |\ |\ |\ |\ |\ |\ |\
pharmacology
study of effect of drugs in man (as compared to animals or
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
comparative pharmacology - CORRECT ANSWERS ✔✔Define |\ |\ |\ |\ |\ |\
clinical pharmacology |\
also known as therapeutics, pharmacotherapeutics emphasizes
|\ |\ |\ |\ |\ |\
the disease state and its characteristics including therapy for and
|\ |\ |\ |\ |\ |\ |\ |\ |\
use of drugs in prevention and treatment of condition - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔what are pharmacotherapeutics?
|\ |\ |\ |\
Drugs used to destroy or eliminate pathogenic cells or organisms.
|\ |\ |\ |\ |\ |\ |\ |\ |\
The term is usually restricted to anti-infectives and cancer
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
chemotherapy. - CORRECT ANSWERS ✔✔what are |\ |\ |\ |\ |\ |\
chemotherapeutic agents? |\
Toxicology deals with the effects of drugs. Toxicity is measured
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
through the Therapeutic Index. - CORRECT ANSWERS ✔✔what is
|\ |\ |\ |\ |\ |\ |\ |\ |\
toxicology and how do we measure a drugs toxicity?
|\ |\ |\ |\ |\ |\ |\ |\
,therapeutic index is a ratio that measures toxicity. The ratio is
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
found by putting the dose *capable of killing 50% of animals
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
(LD50) over than required to acheive a beneficial effect in 50% of
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
animals (ED50).
|\ |\ |\
In clinical practice the THERAPEUTIC INDEX is described as the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
ratio of the dose that causes toxicity over the dose that provides
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
therapeutic effect. - CORRECT ANSWERS ✔✔What is the |\ |\ |\ |\ |\ |\ |\ |\
therapeutic index? |\
Tolerance is the hyporeactivity that occurring from chronic
|\ |\ |\ |\ |\ |\ |\ |\
exposure to a drug. Achievement of the same effects of the drug
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
requires larger and larger doses. - CORRECT ANSWERS ✔✔what is
|\ |\ |\ |\ |\ |\ |\ |\ |\
tolerance?
|\
Cross tolerance may happen when tolerance occurs across drugs
|\ |\ |\ |\ |\ |\ |\ |\ |\
of the same class or across drugs that have the same
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
pharmacological effects - CORRECT ANSWERS ✔✔What is cross |\ |\ |\ |\ |\ |\ |\ |\
tolerance and how does it occur? |\ |\ |\ |\ |\
Tolerance to opioids, barbiturates, and alcohol - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔what are some examples of neurological
|\ |\ |\ |\ |\ |\ |\
adaptation/ cellular tolerance to drugs? |\ |\ |\ |\
metabolic drug tolerance occurs when the body has an increased
|\ |\ |\ |\ |\ |\ |\ |\ |\
rate of elimination of the drug. - CORRECT ANSWERS ✔✔What is
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
metabolic drug tolerance? |\ |\
, enzyme induction which occurs when there is an increased
|\ |\ |\ |\ |\ |\ |\ |\ |\
activity of enzymes (the drug transport system) - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔what is the most common form of metabolic |\ |\ |\ |\ |\ |\ |\ |\ |\
tolerance?
pharmacodynamic processes determine the nature and intensity |\ |\ |\ |\ |\ |\ |\
of the response. It is essentially the effect of the drug ON the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
body.
EX: Target Organ, receptors, proteins, physiological effect etc. -
|\ |\ |\ |\ |\ |\ |\ |\ |\
CORRECT ANSWERS ✔✔What is pharmacodynamics? |\ |\ |\ |\
Pharmacokinetic processes determine how much of an admin- |\ |\ |\ |\ |\ |\ |\ |\
istered dose gets to its sites of action. There are four major
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
pharmacokinetic processes: (1) drug absorption, (2) drug |\ |\ |\ |\ |\ |\ |\
distribution, (3) drug metabolism, and (4) drug excretion. *These |\ |\ |\ |\ |\ |\ |\ |\ |\
processes can be thought of as the impact of the body on drugs*
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
- CORRECT ANSWERS ✔✔What is pharmacokinetics?
|\ |\ |\ |\ |\ |\
what are the four major pharmacokinetic processes?
|\ |\ |\ |\ |\ |\
Down regulation - CORRECT ANSWERS ✔✔what type of tolerance
|\ |\ |\ |\ |\ |\ |\ |\ |\
occurs when there is a decrease in the number, or decrease in
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
the sensitivity, of receptor sites?
|\ |\ |\ |\
betablockers - CORRECT ANSWERS ✔✔what kind of drugs block |\ |\ |\ |\ |\ |\ |\ |\ |\
receptors?
