age 1 of 33
PTCB CSPT FINAL EXAM STUDY GUIDE 2025/2026
ACCURATE QUESTIONS AND CORRECT DETAILED
ANSWERS WITH RATIONALES || 100% GUARANTEED
PASS <LATEST VERSION>
Patient harmed by compounded sterile preparations
.......Answer.........microbial contamination, excessive bacterial
endotoxins, variability in strength of ingredients,
chemical/physical contaminants, inappropriate quality of
ingredients
non sterile compounding examples .......Answer.........products used
orally, topically on skin or to fill gaps when not commercially
available
aesptic .......Answer.........state of being free from microbial
contamination
,age 2 of 33
sterile compounded items .......Answer.........injections(iv, etc)
ophthalmic drops, aqueous bronchial or nasal inhalations, baths
for live organs, tissue implants, irrigation for wounds or cavities
Non hazardous hoods .......Answer.........Laminar airflow
workbench (LAFW) compounding containment isolator (CAI)
Hazardous hoods .......Answer.........biological safety cabinet
(BSC) compounding aseptic containment isolator (CACI)
Primary Engineering Control (PEC) .......Answer.........a device or
room that provides an ISO Class 5 environment for the exposure
of critical sites when compounding CSPs. Such devices include,
but may not be limited to, laminar airflow workbenches (LAFWs),
biological safety cabinets (BSCs), compounding aseptic isolators
(CAIs), and compounding aseptic containment isolators (CACIs).
,age 3 of 33
secondary engineering controls .......Answer.........the ante area
and buffer area
Buffer or Clean Room .......Answer.........ISO 7
Ante Room ISO class .......Answer.........ISO 8, unless provides
access to negative pressure room then ISO 7
vertical hood .......Answer.........hazardous compounding-air flows
vertically
Horizontal Hood .......Answer.........air flows horizontally across the
work area from back to front
Direct Compounding Area (DCA) .......Answer.........- a critical
area within the hood (ISO Class 5) where areas are exposed to
filtered air; also known as "first air"
Negative Pressure room .......Answer.........Hazardous materials
, age 4 of 33
High-efficiency particulate air (HEPA) filters
.......Answer.........remove microbes > 0.3 micrometers
Ante Room .......Answer.........washing, garbing, product
decontamination
Buffer area air change per hour (APCH) .......Answer.........30
exchanges per hour
ante room air change per hour (APCH) .......Answer.........ISO 8-20
per hour ISO 7- 30 per hour
Cleaning of compounding area .......Answer.........germicidal
detergent & water for visible solids, 70% isopropyl alcohol
ISO Class 5 PEC cleaned .......Answer.........beginning of each shift,
before each batch, every 30 minus when compounding, after
spills, contamination
PTCB CSPT FINAL EXAM STUDY GUIDE 2025/2026
ACCURATE QUESTIONS AND CORRECT DETAILED
ANSWERS WITH RATIONALES || 100% GUARANTEED
PASS <LATEST VERSION>
Patient harmed by compounded sterile preparations
.......Answer.........microbial contamination, excessive bacterial
endotoxins, variability in strength of ingredients,
chemical/physical contaminants, inappropriate quality of
ingredients
non sterile compounding examples .......Answer.........products used
orally, topically on skin or to fill gaps when not commercially
available
aesptic .......Answer.........state of being free from microbial
contamination
,age 2 of 33
sterile compounded items .......Answer.........injections(iv, etc)
ophthalmic drops, aqueous bronchial or nasal inhalations, baths
for live organs, tissue implants, irrigation for wounds or cavities
Non hazardous hoods .......Answer.........Laminar airflow
workbench (LAFW) compounding containment isolator (CAI)
Hazardous hoods .......Answer.........biological safety cabinet
(BSC) compounding aseptic containment isolator (CACI)
Primary Engineering Control (PEC) .......Answer.........a device or
room that provides an ISO Class 5 environment for the exposure
of critical sites when compounding CSPs. Such devices include,
but may not be limited to, laminar airflow workbenches (LAFWs),
biological safety cabinets (BSCs), compounding aseptic isolators
(CAIs), and compounding aseptic containment isolators (CACIs).
,age 3 of 33
secondary engineering controls .......Answer.........the ante area
and buffer area
Buffer or Clean Room .......Answer.........ISO 7
Ante Room ISO class .......Answer.........ISO 8, unless provides
access to negative pressure room then ISO 7
vertical hood .......Answer.........hazardous compounding-air flows
vertically
Horizontal Hood .......Answer.........air flows horizontally across the
work area from back to front
Direct Compounding Area (DCA) .......Answer.........- a critical
area within the hood (ISO Class 5) where areas are exposed to
filtered air; also known as "first air"
Negative Pressure room .......Answer.........Hazardous materials
, age 4 of 33
High-efficiency particulate air (HEPA) filters
.......Answer.........remove microbes > 0.3 micrometers
Ante Room .......Answer.........washing, garbing, product
decontamination
Buffer area air change per hour (APCH) .......Answer.........30
exchanges per hour
ante room air change per hour (APCH) .......Answer.........ISO 8-20
per hour ISO 7- 30 per hour
Cleaning of compounding area .......Answer.........germicidal
detergent & water for visible solids, 70% isopropyl alcohol
ISO Class 5 PEC cleaned .......Answer.........beginning of each shift,
before each batch, every 30 minus when compounding, after
spills, contamination
