HCD & R Module 4 Questions with Answers
(100% Correct Answers)
Factors consumed in a clot Answer: I, II, V, VIII, and XIII
Vitamin K dependent factors Answer: II, VII, IX, X
Labile factor Answer: V, VIII
Factors NOT found in serum Answer: I, II, V, VIII, and XIII
Factors removed by absorption with barium sulfate Answer: II, VII, IX, X
Contact factors Answer: XII, XI, Fletcher and Fitzgerald
Factors affected by coumadin Answer: II, VII, IX, X
Common path factors Answer: I, II, V, X
Factor XIII deficiency Answer: Normal PT and PTT
Measured with urea solubility
Treat with cryoprecipitate
Factor XII deficiency Answer: Normal PT
Increased PTT
Causes thrombosis NOT bleeding
Factor X deficiency Answer: Increased PT and PTT
Factor IX deficiency Answer: Normal PT
Increased PTT
Hemophilia B (Christmas disease)
Factor VII deficiency Answer: Increased PT
, 2
Normal PTT
Factor I deficiency Answer: Increased PT and PTT
Measured by thrombin time
Treat with cryoprecipitate
Where are most plasma coag factors produced? Answer: Liver
What happens with plasma coag factors in liver disease? Answer: Production is
reduced
When the concentration of factors is ___________, the coag test will be
__________? Answer: When the concentration of factors is REDUCED, the
coag test will be PROLONGED
Where is Factor VIII partly produced? Answer: Vessel endothelial cells and is
an acute phase reactant
Factor VIII in liver disease? Answer: Normal or increased
What is trypsin? Answer: An antifibrinolytic
What does trypsin prevent? Answer: In vitro fibrinolysis
What does trypsin action allow? Answer: The test to detect only the in vivo
fibrinolysis that occurred in the patient's blood PRIOR to collection
Positive FSP and a normal or negative D-Dimer. Diagnosis? Answer: Primary
fibrinogenolysis
Positive FSP and a positive or increased D-Dimer. Diagnosis? Answer: DIC
Unique to the EXTRINSIC coag pathway? Answer: III and VII
Unique to the INTRINSIC coag pathway? Answer: XII, XI, IX, VIII
Therapeutic range for INR for patients on Coumadin? Answer: 2.0 - 3.0
(100% Correct Answers)
Factors consumed in a clot Answer: I, II, V, VIII, and XIII
Vitamin K dependent factors Answer: II, VII, IX, X
Labile factor Answer: V, VIII
Factors NOT found in serum Answer: I, II, V, VIII, and XIII
Factors removed by absorption with barium sulfate Answer: II, VII, IX, X
Contact factors Answer: XII, XI, Fletcher and Fitzgerald
Factors affected by coumadin Answer: II, VII, IX, X
Common path factors Answer: I, II, V, X
Factor XIII deficiency Answer: Normal PT and PTT
Measured with urea solubility
Treat with cryoprecipitate
Factor XII deficiency Answer: Normal PT
Increased PTT
Causes thrombosis NOT bleeding
Factor X deficiency Answer: Increased PT and PTT
Factor IX deficiency Answer: Normal PT
Increased PTT
Hemophilia B (Christmas disease)
Factor VII deficiency Answer: Increased PT
, 2
Normal PTT
Factor I deficiency Answer: Increased PT and PTT
Measured by thrombin time
Treat with cryoprecipitate
Where are most plasma coag factors produced? Answer: Liver
What happens with plasma coag factors in liver disease? Answer: Production is
reduced
When the concentration of factors is ___________, the coag test will be
__________? Answer: When the concentration of factors is REDUCED, the
coag test will be PROLONGED
Where is Factor VIII partly produced? Answer: Vessel endothelial cells and is
an acute phase reactant
Factor VIII in liver disease? Answer: Normal or increased
What is trypsin? Answer: An antifibrinolytic
What does trypsin prevent? Answer: In vitro fibrinolysis
What does trypsin action allow? Answer: The test to detect only the in vivo
fibrinolysis that occurred in the patient's blood PRIOR to collection
Positive FSP and a normal or negative D-Dimer. Diagnosis? Answer: Primary
fibrinogenolysis
Positive FSP and a positive or increased D-Dimer. Diagnosis? Answer: DIC
Unique to the EXTRINSIC coag pathway? Answer: III and VII
Unique to the INTRINSIC coag pathway? Answer: XII, XI, IX, VIII
Therapeutic range for INR for patients on Coumadin? Answer: 2.0 - 3.0
