Assignment Probiotics
Verteer en verweer I
Bachelor 1 – 2019/2020
Herraets, C.C.H.A.
I6205930
Group 24
Faculty of Health, Medicine and Life Sciences (FHML)
Maastricht University
Course GNK1105
June 2020
, Clinical question
Should probiotics versus no treatment be used in patients who suffer from infectious diarrhea?
Order of importance of outcome measures:
1. The incidence and duration of infectious diarrhea
2. Side effects of the use of probiotics
Selection of literature
The papers selected for use based on the PICO questions are:
- Lönnermark E, Lappas G, Friman V, Wold AE, Backhaus E, Adlerberth I. (2015).
Effects of probiotic intake and gender on non typhoid Salmonella infection. Journal of
Clinical Gastroenterology, 49(2), 116-23.
- Buydens, P., Debeuckelaere, S. (1996). Efficacy of sf 68 in the treatment of acute
diarrhea. a placebo-controlled trial. Scandinavian Journal of Gastroenterology, 31(9),
887-891.
The papers not selected for used based on the PICO question are:
- Canani RB, Cirillo P, Terrin G, Cesarano L, Spagnuolo MI, Vincenzo A, et al. (2007).
Probiotics for treatment of acute diarrhea in children: randomised clinical trial of five
different preparations. British Medical Journal, 335(7615), 340.
This paper is not selected because the research population are children. This is not
relevant, because the recommendation is written for an adult.
- Cimperman, L., Bayless, G., Best, K., Diligente, A., Mordarski, B., Oster, M., et al.
(2011). A randomized, double-blind, placebo-controlled pilot study of lactobacillus
reuteri atcc 55730 for the prevention of antibiotic-associated diarrhea in hospitalized
adults. Journal of Clinical Gastroenterology, 45(9), 785-9.
doi:10.1097/MCG.0b013e3182166a42
This paper is not selected because the research population is too small, and for that
reason not as reliable.
- Pereg, D., Kimhi, O., Tirosh, A., Orr, N., Kayouf, R., & Lishner, M. (2005). The
effect of fermented yogurt on the prevention of diarrhea in a healthy adult population.
American Journal of Infection Control, 33(2), 122-125.
This paper is not selected because it focusses on the prevention of diarrhea rather
than treatment during diarrhea. The patient the recommendation is written for
already suffers from diarrhea, and therefor this paper is irrelevant.
- Szajewska, H., Guarino, A., Hojsak, I., Indrio, F., Kolacek, S., Shamir, R., et al.
(2014). Use of probiotics for management of acute gastroenteritis: A position paper by
the espghan working group for probiotics and prebiotics. Journal of Pediatric
Gastroenterology and Nutrition, 58(4), 531-539.
doi:10.1097/MPG.0000000000000320
This paper is not selected because the study population are children. This is not
relevant because the recommendation is written for an adult.
- The Lancet. (2008). Probiotics or con? Lancet, 23, 371(9613), 624.
Verteer en verweer I
Bachelor 1 – 2019/2020
Herraets, C.C.H.A.
I6205930
Group 24
Faculty of Health, Medicine and Life Sciences (FHML)
Maastricht University
Course GNK1105
June 2020
, Clinical question
Should probiotics versus no treatment be used in patients who suffer from infectious diarrhea?
Order of importance of outcome measures:
1. The incidence and duration of infectious diarrhea
2. Side effects of the use of probiotics
Selection of literature
The papers selected for use based on the PICO questions are:
- Lönnermark E, Lappas G, Friman V, Wold AE, Backhaus E, Adlerberth I. (2015).
Effects of probiotic intake and gender on non typhoid Salmonella infection. Journal of
Clinical Gastroenterology, 49(2), 116-23.
- Buydens, P., Debeuckelaere, S. (1996). Efficacy of sf 68 in the treatment of acute
diarrhea. a placebo-controlled trial. Scandinavian Journal of Gastroenterology, 31(9),
887-891.
The papers not selected for used based on the PICO question are:
- Canani RB, Cirillo P, Terrin G, Cesarano L, Spagnuolo MI, Vincenzo A, et al. (2007).
Probiotics for treatment of acute diarrhea in children: randomised clinical trial of five
different preparations. British Medical Journal, 335(7615), 340.
This paper is not selected because the research population are children. This is not
relevant, because the recommendation is written for an adult.
- Cimperman, L., Bayless, G., Best, K., Diligente, A., Mordarski, B., Oster, M., et al.
(2011). A randomized, double-blind, placebo-controlled pilot study of lactobacillus
reuteri atcc 55730 for the prevention of antibiotic-associated diarrhea in hospitalized
adults. Journal of Clinical Gastroenterology, 45(9), 785-9.
doi:10.1097/MCG.0b013e3182166a42
This paper is not selected because the research population is too small, and for that
reason not as reliable.
- Pereg, D., Kimhi, O., Tirosh, A., Orr, N., Kayouf, R., & Lishner, M. (2005). The
effect of fermented yogurt on the prevention of diarrhea in a healthy adult population.
American Journal of Infection Control, 33(2), 122-125.
This paper is not selected because it focusses on the prevention of diarrhea rather
than treatment during diarrhea. The patient the recommendation is written for
already suffers from diarrhea, and therefor this paper is irrelevant.
- Szajewska, H., Guarino, A., Hojsak, I., Indrio, F., Kolacek, S., Shamir, R., et al.
(2014). Use of probiotics for management of acute gastroenteritis: A position paper by
the espghan working group for probiotics and prebiotics. Journal of Pediatric
Gastroenterology and Nutrition, 58(4), 531-539.
doi:10.1097/MPG.0000000000000320
This paper is not selected because the study population are children. This is not
relevant because the recommendation is written for an adult.
- The Lancet. (2008). Probiotics or con? Lancet, 23, 371(9613), 624.
