MICROB 3200 – Final Exam (Virus Classification) Exam
Questions And Correct Answers (Verified Answers) Plus
Rationales 2025 Q&A | Instant Download Pdf
based on general virology principles with a focus on virus taxonomy, structure, genome types,
replication strategies, and Baltimore classification
1. Which Baltimore class of viruses includes double-stranded DNA viruses?
A. I
B. II
C. III
D. IV
A
Class I includes double-stranded DNA viruses, which use host machinery for
transcription.
2. Single-stranded DNA viruses belong to which Baltimore classification?
A. I
B. II
C. V
D. VI
B
Class II viruses have single-stranded DNA genomes that must be converted
to double-stranded DNA before transcription.
3. Which virus family is known for having an envelope and a negative-sense
RNA genome?
, A. Adenoviridae
B. Herpesviridae
C. Orthomyxoviridae
D. Papillomaviridae
C
Orthomyxoviridae includes influenza viruses, which are enveloped and have
segmented negative-sense RNA genomes.
4. Which virus family includes viruses with a reverse transcription step but a
DNA genome?
A. Retroviridae
B. Reoviridae
C. Hepadnaviridae
D. Picornaviridae
C
Hepadnaviruses (e.g., hepatitis B virus) are Class VII: partially double-
stranded DNA viruses that replicate through an RNA intermediate.
5. Which of the following best describes Baltimore Class IV viruses?
A. Double-stranded RNA
B. Positive-sense RNA
C. Negative-sense RNA
D. DNA viruses with RNA intermediate
B
Class IV viruses have positive-sense RNA genomes that can be directly
translated into protein.
,6. Which family of viruses is double-stranded RNA and segmented?
A. Poxviridae
B. Retroviridae
C. Reoviridae
D. Flaviviridae
C
Reoviridae (e.g., rotavirus) are double-stranded RNA viruses with
segmented genomes.
7. Retroviruses belong to which Baltimore classification?
A. IV
B. V
C. VI
D. VII
C
Class VI viruses are positive-sense RNA viruses that replicate via reverse
transcription into DNA.
8. Which of the following virus families replicate entirely in the cytoplasm?
A. Herpesviridae
B. Adenoviridae
C. Poxviridae
D. Parvoviridae
C
Poxviruses are large DNA viruses that replicate in the cytoplasm and carry
their own transcription machinery.
, 9. Which of the following is a characteristic of negative-sense RNA viruses?
A. Their genomes are directly translated
B. They require reverse transcriptase
C. They must carry RNA-dependent RNA polymerase
D. They have DNA genomes
C
Negative-sense RNA viruses require RNA-dependent RNA polymerase to
transcribe their genome into positive-sense RNA.
10.Which virus is in the family Flaviviridae and classified as Class IV?
A. Influenza virus
B. Ebola virus
C. Zika virus
D. Rotavirus
C
Zika virus is a positive-sense RNA virus in the Flaviviridae family, placing it in
Class IV.
11.Which of the following is a segmented RNA virus?
A. Zika virus
B. Influenza virus
C. Measles virus
D. Rabies virus
B
Influenza virus has a segmented negative-sense RNA genome.
Questions And Correct Answers (Verified Answers) Plus
Rationales 2025 Q&A | Instant Download Pdf
based on general virology principles with a focus on virus taxonomy, structure, genome types,
replication strategies, and Baltimore classification
1. Which Baltimore class of viruses includes double-stranded DNA viruses?
A. I
B. II
C. III
D. IV
A
Class I includes double-stranded DNA viruses, which use host machinery for
transcription.
2. Single-stranded DNA viruses belong to which Baltimore classification?
A. I
B. II
C. V
D. VI
B
Class II viruses have single-stranded DNA genomes that must be converted
to double-stranded DNA before transcription.
3. Which virus family is known for having an envelope and a negative-sense
RNA genome?
, A. Adenoviridae
B. Herpesviridae
C. Orthomyxoviridae
D. Papillomaviridae
C
Orthomyxoviridae includes influenza viruses, which are enveloped and have
segmented negative-sense RNA genomes.
4. Which virus family includes viruses with a reverse transcription step but a
DNA genome?
A. Retroviridae
B. Reoviridae
C. Hepadnaviridae
D. Picornaviridae
C
Hepadnaviruses (e.g., hepatitis B virus) are Class VII: partially double-
stranded DNA viruses that replicate through an RNA intermediate.
5. Which of the following best describes Baltimore Class IV viruses?
A. Double-stranded RNA
B. Positive-sense RNA
C. Negative-sense RNA
D. DNA viruses with RNA intermediate
B
Class IV viruses have positive-sense RNA genomes that can be directly
translated into protein.
,6. Which family of viruses is double-stranded RNA and segmented?
A. Poxviridae
B. Retroviridae
C. Reoviridae
D. Flaviviridae
C
Reoviridae (e.g., rotavirus) are double-stranded RNA viruses with
segmented genomes.
7. Retroviruses belong to which Baltimore classification?
A. IV
B. V
C. VI
D. VII
C
Class VI viruses are positive-sense RNA viruses that replicate via reverse
transcription into DNA.
8. Which of the following virus families replicate entirely in the cytoplasm?
A. Herpesviridae
B. Adenoviridae
C. Poxviridae
D. Parvoviridae
C
Poxviruses are large DNA viruses that replicate in the cytoplasm and carry
their own transcription machinery.
, 9. Which of the following is a characteristic of negative-sense RNA viruses?
A. Their genomes are directly translated
B. They require reverse transcriptase
C. They must carry RNA-dependent RNA polymerase
D. They have DNA genomes
C
Negative-sense RNA viruses require RNA-dependent RNA polymerase to
transcribe their genome into positive-sense RNA.
10.Which virus is in the family Flaviviridae and classified as Class IV?
A. Influenza virus
B. Ebola virus
C. Zika virus
D. Rotavirus
C
Zika virus is a positive-sense RNA virus in the Flaviviridae family, placing it in
Class IV.
11.Which of the following is a segmented RNA virus?
A. Zika virus
B. Influenza virus
C. Measles virus
D. Rabies virus
B
Influenza virus has a segmented negative-sense RNA genome.
