LEIK FNP PRACTICE (ACTUAL 2025) QUESTIONS
& VERIFIED ANSWERS LATEST UPDATE
A 72-year-old woman has been on hydrochlorothiazide 12.5
mg for many years to control her Stage II hypertension. Her
blood pressure (BP) at this visit is 168/96. She is currently
complaining of pain on her right hip and on both knees. She
has increased her dose of ibuprofen (Motrin) from 400 mg 3
times day (TID) to 800 mg TID. She is still in pain and would
like something stronger. Which of the following statements is
the best explanation of the effects of ibuprofen (Motrin) on
her disease?
A) It increases the chances of adverse effects to her health
B) It inhibits the effect of renal prostaglandins and blunts the
effectiveness of the diuretic
C) It prolongs the therapeutic effects of hydrochlorothiazide
and other diuretics
D) None of the statements are true
B) It inhibits the effect of renal prostaglandins and blunts the
effectiveness of the diuretic.
NSAIDs and ASA inhibit the vasodilatory effects of
prostaglandins, which predisposes the kidney to ischemia.
NSAIDs and diuretics can cause acute prerenal failure by
decreasing renal blood flow.
,A 68-year-old woman has recently been diagnosed with
polymyalgia rheumatica. The nurse practitioner is discussing
the treatment options with the patient. Which of the following
medications is the first-line treatment for this condition?
A) Etanercept (Enbrel)
B) Oral prednisone
C) Indomethacin
D) Methotrexate
B) Oral prednisone
Patients with PMR are treated with oral steroids
(glucocorticoids). One of the hallmarks of the disorder is the
dramatic improvement of
symptoms after starting treatment with oral prednisone.
Usually, the symptoms can be controlled with long-term (2-3
years) low-dose oral prednisone, which can be tapered when
symptoms are under control. For most patients, PMR is a self-
limiting illness (from a few months to 3 years).
Which of the following is a true statement regarding the first-
pass metabolism process?
,A) Drugs that are administered by intramuscular injection all
go through the process of first-pass metabolism
B) After being swallowed, oral drugs are absorbed by the GI
tract and metabolized by the bacteria in the small intestines
before being released into the general circulation
C) Drugs administered through the skin (patches) are
metabolized by the dermis of the skin
D) After a drug is taken by the oral route, it is absorbed in the
small intestines and enters the liver through the portal
circulation, where it is metabolized before being released into
the general circulation
D) After a drug is taken by the oral route, it is absorbed in the
small intestines and enters the liver through the portal
circulation, where it is metabolized before being released into
the general circulation
After drugs are taken by the oral route, they are absorbed by
the small intestines and enter the liver through the portal
circulation, where they are metabolized before being released
into the
general circulation. First-pass metabolism (first-pass effect)
determines how much of the active drug is available to the
body (bioavailability). Depending on the drug and other
factors, a drug may be poorly metabolized or extensively
metabolized by the liver.
, The nurse practitioner orders an ankle-brachial index (ABI)
test for a patient. Which of the following disorders is the ABI
test used for?
A) Venous insufficiency
B) Osteoarthritis of the arm or the ankle
C) Peripheral arterial disease (PAD)
D) Rheumatoid arthritis
C) Peripheral arterial disease (PAD)
The ankle-brachial index (ABI) is a test that is used to stratify
the severity of arterial blockage in the lower extremities for
patients with peripheral arterial disease (PAD). An ABI score
of 1.0 to 1.4 is
normal. Any value less than 1.0 is abnormal. A score of 0.5 or
less is indicative of severe PAD.
We have an expert-written solution to this problem!
A college student is seen as a walk-in appointment in a
college health clinic. She complains of the abrupt onset of
sore throat, nasal congestion, runny nose, and malaise. Vital
& VERIFIED ANSWERS LATEST UPDATE
A 72-year-old woman has been on hydrochlorothiazide 12.5
mg for many years to control her Stage II hypertension. Her
blood pressure (BP) at this visit is 168/96. She is currently
complaining of pain on her right hip and on both knees. She
has increased her dose of ibuprofen (Motrin) from 400 mg 3
times day (TID) to 800 mg TID. She is still in pain and would
like something stronger. Which of the following statements is
the best explanation of the effects of ibuprofen (Motrin) on
her disease?
A) It increases the chances of adverse effects to her health
B) It inhibits the effect of renal prostaglandins and blunts the
effectiveness of the diuretic
C) It prolongs the therapeutic effects of hydrochlorothiazide
and other diuretics
D) None of the statements are true
B) It inhibits the effect of renal prostaglandins and blunts the
effectiveness of the diuretic.
NSAIDs and ASA inhibit the vasodilatory effects of
prostaglandins, which predisposes the kidney to ischemia.
NSAIDs and diuretics can cause acute prerenal failure by
decreasing renal blood flow.
,A 68-year-old woman has recently been diagnosed with
polymyalgia rheumatica. The nurse practitioner is discussing
the treatment options with the patient. Which of the following
medications is the first-line treatment for this condition?
A) Etanercept (Enbrel)
B) Oral prednisone
C) Indomethacin
D) Methotrexate
B) Oral prednisone
Patients with PMR are treated with oral steroids
(glucocorticoids). One of the hallmarks of the disorder is the
dramatic improvement of
symptoms after starting treatment with oral prednisone.
Usually, the symptoms can be controlled with long-term (2-3
years) low-dose oral prednisone, which can be tapered when
symptoms are under control. For most patients, PMR is a self-
limiting illness (from a few months to 3 years).
Which of the following is a true statement regarding the first-
pass metabolism process?
,A) Drugs that are administered by intramuscular injection all
go through the process of first-pass metabolism
B) After being swallowed, oral drugs are absorbed by the GI
tract and metabolized by the bacteria in the small intestines
before being released into the general circulation
C) Drugs administered through the skin (patches) are
metabolized by the dermis of the skin
D) After a drug is taken by the oral route, it is absorbed in the
small intestines and enters the liver through the portal
circulation, where it is metabolized before being released into
the general circulation
D) After a drug is taken by the oral route, it is absorbed in the
small intestines and enters the liver through the portal
circulation, where it is metabolized before being released into
the general circulation
After drugs are taken by the oral route, they are absorbed by
the small intestines and enter the liver through the portal
circulation, where they are metabolized before being released
into the
general circulation. First-pass metabolism (first-pass effect)
determines how much of the active drug is available to the
body (bioavailability). Depending on the drug and other
factors, a drug may be poorly metabolized or extensively
metabolized by the liver.
, The nurse practitioner orders an ankle-brachial index (ABI)
test for a patient. Which of the following disorders is the ABI
test used for?
A) Venous insufficiency
B) Osteoarthritis of the arm or the ankle
C) Peripheral arterial disease (PAD)
D) Rheumatoid arthritis
C) Peripheral arterial disease (PAD)
The ankle-brachial index (ABI) is a test that is used to stratify
the severity of arterial blockage in the lower extremities for
patients with peripheral arterial disease (PAD). An ABI score
of 1.0 to 1.4 is
normal. Any value less than 1.0 is abnormal. A score of 0.5 or
less is indicative of severe PAD.
We have an expert-written solution to this problem!
A college student is seen as a walk-in appointment in a
college health clinic. She complains of the abrupt onset of
sore throat, nasal congestion, runny nose, and malaise. Vital
