Summary – Apoptosis
Source: Freepik
Written by: Abduallah Lemdjad
Date: 26-03-2024
,Course: Apoptosis
, Table of Contents
Lecture 1 – Cell death and Apoptosis..................................................................................4
Lecture 2- Cell death signalling...........................................................................................6
2.1 The Fas receptor.....................................................................................................................6
2.2 The DR4 and DR5....................................................................................................................7
2.3 The tumour necrosis factor (TNF) receptor.............................................................................7
2.4 The activation of caspase-8.....................................................................................................9
2.5 The activation of caspase-9.....................................................................................................9
2.6 The role of IAP in the inhibition of apoptosis..........................................................................9
Lecture 3 – The role of cell death in inflammation and the intrinsic apoptotic pathway....11
3.1 The activation of procaspase-1 induces inflammation...........................................................11
3.2 The intrinsic apoptotic pathway (cellular stress signals)........................................................12
Lecture 4 – Immunity and Apoptosis.................................................................................16
4.1 Role of apoptosis in the adaptive immune system................................................................16
4.3 Role of apoptosis in viral infections.......................................................................................16
4.4 Methods to detect and quantify apoptosis...........................................................................18
Lecture 5 – Apoptosis and stress.......................................................................................19
Source: Freepik
Written by: Abduallah Lemdjad
Date: 26-03-2024
,Course: Apoptosis
, Table of Contents
Lecture 1 – Cell death and Apoptosis..................................................................................4
Lecture 2- Cell death signalling...........................................................................................6
2.1 The Fas receptor.....................................................................................................................6
2.2 The DR4 and DR5....................................................................................................................7
2.3 The tumour necrosis factor (TNF) receptor.............................................................................7
2.4 The activation of caspase-8.....................................................................................................9
2.5 The activation of caspase-9.....................................................................................................9
2.6 The role of IAP in the inhibition of apoptosis..........................................................................9
Lecture 3 – The role of cell death in inflammation and the intrinsic apoptotic pathway....11
3.1 The activation of procaspase-1 induces inflammation...........................................................11
3.2 The intrinsic apoptotic pathway (cellular stress signals)........................................................12
Lecture 4 – Immunity and Apoptosis.................................................................................16
4.1 Role of apoptosis in the adaptive immune system................................................................16
4.3 Role of apoptosis in viral infections.......................................................................................16
4.4 Methods to detect and quantify apoptosis...........................................................................18
Lecture 5 – Apoptosis and stress.......................................................................................19
