Nurs6501ADVANCED PATHOPHYSIOLOGY Quiz 2

A runner has depleted all the oxygen available for muscle energy. Which of the following will facilitate his continued muscle performance? - Answer: Anaerobic glycolysis What causes the rapid change in the resting membrane potential that initiates an action potential? - Answer: Sodium gates open, and sodium rushes into the cell, changing the membrane potential from negative to positive. A 12-year-old male is diagnosed with Klinefelter syndrome. His karyotype would reveal which of the following? - Answer: XXY A nurse is reviewing the pedigree chart. When checking for a proband, what is the nurse looking for? - Answer: The person who is first diagnosed with a genetic disease An aide asks the nurse why people who have neurofibromatosis will show varying degrees of the disease. Which genetic principle should the nurse explain to the aide? - Answer: Expressivity In teaching a patient with cirrhosis, which information should the nurse include regarding cholesterol? - Answer: Cholesterol decreases the membrane fluidity of the erythrocyte, which reduces its ability to carry oxygen. A 15-year-old female is diagnosed with Prader-Willi syndrome. This condition is an example of: - Answer: Gene imprinting When a patient asks what causes cystic fibrosis, how should the nurse respond? Cystic fibrosis is caused by an _____ gene - Answer: Autosomal recessive How are potassium and sodium transported across plasma membranes? - Answer: By adenosine triphosphate enzyme (ATPase) The nurse would be correct in identifying the predominant extracellular cation as: - Answer: Sodium The early dilation (swelling) of the cell's endoplasmic reticulum results in: - Answer: Reduced protein synthesis What principle should the nurse remember when trying to distinguish aging from diseases? - Answer: It is difficult to tell the difference because both processes are believed to result from cell injury. What is the diagnosis of a 13-year-old female who has a karyotype that reveals an absent homologous X chromosome with only a single X chromosome present? Her features include a short stature, widely spaced nipples, reduced carrying angle at the elbow, and sparse body hair. - Answer: Turner syndrome A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of the genetic information be contained? - Answer: Nucleolus The nurse is teaching staff about the most common cause of Down syndrome. What is the nurse describing? - Answer: Maternal nondisjunction A 50-year-old male was recently diagnosed with Huntington disease. Transmission of this disease is associated with: - Answer: Delayed age of onset A patient wants to know the risk factors for Down syndrome. What is the nurse's best response? - Answer: Pregnancy in women over age 35 What is the role of cytokines in cell reproduction? - Answer: Provide growth factor for tissue growth and development A newborn male is diagnosed with albinism based on skin, eye, and hair appearance. Which finding will support this diagnosis? - Answer: Inability to convert tyrosine to DOPA (3,4 dihydroxyphenylalanine) Sodium and water accumulation in an injured cell are a direct result of: - Answer: