Legenda:
Nagekeken
Vragen over
Informatie over toets
Inhoudsopgave
Theme 1 Introduction immune system................................................................................................... 2
LC1....................................................................................................................................................... 2
CA1 Introduction ................................................................................................................................. 6
SSA 1.................................................................................................................................................... 7
Theme 2 Innate immunity..................................................................................................................... 15
LC2..................................................................................................................................................... 15
SSA 2.................................................................................................................................................. 18
Theme 3 MHC complex structure and function, and antigen processing ............................................ 31
LC3..................................................................................................................................................... 31
SSA 3.................................................................................................................................................. 33
Theme 4 T cell development and T cell receptor + signaling ................................................................ 36
LC4..................................................................................................................................................... 36
SSA 4.................................................................................................................................................. 44
Theme 5 B cell development and B cell receptor and antibodies + signaling ...................................... 53
LC5..................................................................................................................................................... 53
CA4/5 flow cytometry B and T cells .................................................................................................. 72
SSA 5.................................................................................................................................................. 59
PA5 antibodies (graded) ....................................................................................................................... 73
Theme 6 Cellular immunity ................................................................................................................... 77
LC 6 .................................................................................................................................................... 77
SSA 6.................................................................................................................................................. 79
Theme 7 Humoral immunity ................................................................................................................. 84
LC7..................................................................................................................................................... 84
CA7 Humoral techniques .................................................................................................................. 95
SSA 7.................................................................................................................................................. 88
Theme 8 Infection and immunodeficiency ........................................................................................... 97
LC8..................................................................................................................................................... 97
SSA 8................................................................................................................................................ 102
Theme 9 Tumor immunology.............................................................................................................. 110
LC9................................................................................................................................................... 110
, SSA 9................................................................................................................................................ 114
Theme 10 tolerance and autoimmunity ............................................................................................. 116
LC10................................................................................................................................................. 116
SSA 10.............................................................................................................................................. 122
Overview theme 1-7 (basics of immunology) .......................................... Error! Bookmark not defined.
Q&A theme 1-7 ........................................................................................ Error! Bookmark not defined.
Theme 11 Transplantation .................................................................................................................. 136
LC11................................................................................................................................................. 136
SSA 11.............................................................................................................................................. 138
Theme 12 Manipulation...................................................................................................................... 142
LC12................................................................................................................................................. 142
SSA 12.............................................................................................................................................. 145
Intermezzo Covid vaccines .................................................................................................................. 147
Q&A theme 1-12 group 1 .................................................................................................................... 148
CA overview immunology ........................................................................ Error! Bookmark not defined.
Johan van der Vlag coordinator, Head of nephrology research at RadboudUMC, kidney diseases and
transplantation.
Each theme has a lecture, SSA and responsive lecture
PA theme 5 on campus, PA theme 4/5 and 7 virtual are graded (20% of final grade)
All lectures will be recorded. PowerPoint files will be on BS
2 discussion for a (organizational, like comments and feedback, and content questions)
in case of problems or absence
Study load decreases during time
Studymaterial: textbook (largest part). Keep up with studying!
Theme 1 Introduction immune system
LC1
Immunity: consists of tissues, cells and humoral components
,
, 3 phases:
1. Recognition phase (danger, receptors are key, they arise in B/T cells)
2. Induction phase (immune response or tolerance, which type of response)
3. Effector phase (effector mechanisms, then immune response terminated, memory
established and maintained)
Nagekeken
Vragen over
Informatie over toets
Inhoudsopgave
Theme 1 Introduction immune system................................................................................................... 2
LC1....................................................................................................................................................... 2
CA1 Introduction ................................................................................................................................. 6
SSA 1.................................................................................................................................................... 7
Theme 2 Innate immunity..................................................................................................................... 15
LC2..................................................................................................................................................... 15
SSA 2.................................................................................................................................................. 18
Theme 3 MHC complex structure and function, and antigen processing ............................................ 31
LC3..................................................................................................................................................... 31
SSA 3.................................................................................................................................................. 33
Theme 4 T cell development and T cell receptor + signaling ................................................................ 36
LC4..................................................................................................................................................... 36
SSA 4.................................................................................................................................................. 44
Theme 5 B cell development and B cell receptor and antibodies + signaling ...................................... 53
LC5..................................................................................................................................................... 53
CA4/5 flow cytometry B and T cells .................................................................................................. 72
SSA 5.................................................................................................................................................. 59
PA5 antibodies (graded) ....................................................................................................................... 73
Theme 6 Cellular immunity ................................................................................................................... 77
LC 6 .................................................................................................................................................... 77
SSA 6.................................................................................................................................................. 79
Theme 7 Humoral immunity ................................................................................................................. 84
LC7..................................................................................................................................................... 84
CA7 Humoral techniques .................................................................................................................. 95
SSA 7.................................................................................................................................................. 88
Theme 8 Infection and immunodeficiency ........................................................................................... 97
LC8..................................................................................................................................................... 97
SSA 8................................................................................................................................................ 102
Theme 9 Tumor immunology.............................................................................................................. 110
LC9................................................................................................................................................... 110
, SSA 9................................................................................................................................................ 114
Theme 10 tolerance and autoimmunity ............................................................................................. 116
LC10................................................................................................................................................. 116
SSA 10.............................................................................................................................................. 122
Overview theme 1-7 (basics of immunology) .......................................... Error! Bookmark not defined.
Q&A theme 1-7 ........................................................................................ Error! Bookmark not defined.
Theme 11 Transplantation .................................................................................................................. 136
LC11................................................................................................................................................. 136
SSA 11.............................................................................................................................................. 138
Theme 12 Manipulation...................................................................................................................... 142
LC12................................................................................................................................................. 142
SSA 12.............................................................................................................................................. 145
Intermezzo Covid vaccines .................................................................................................................. 147
Q&A theme 1-12 group 1 .................................................................................................................... 148
CA overview immunology ........................................................................ Error! Bookmark not defined.
Johan van der Vlag coordinator, Head of nephrology research at RadboudUMC, kidney diseases and
transplantation.
Each theme has a lecture, SSA and responsive lecture
PA theme 5 on campus, PA theme 4/5 and 7 virtual are graded (20% of final grade)
All lectures will be recorded. PowerPoint files will be on BS
2 discussion for a (organizational, like comments and feedback, and content questions)
in case of problems or absence
Study load decreases during time
Studymaterial: textbook (largest part). Keep up with studying!
Theme 1 Introduction immune system
LC1
Immunity: consists of tissues, cells and humoral components
,
, 3 phases:
1. Recognition phase (danger, receptors are key, they arise in B/T cells)
2. Induction phase (immune response or tolerance, which type of response)
3. Effector phase (effector mechanisms, then immune response terminated, memory
established and maintained)
