Exercise?
Ultimate test for the regulation of homeostasis in many organ systems
Cardiovascular and respiratory systems play a key role
Learning goals
1. Regulation of metabolism
2. Aerobic exercise capacity
3. Cardiovascular and Respiratory adaptations
Regulation of metabolism
Metabolism and exercise
• What are the primary substrates used for energy production?
• Which substrates are used for short term maximal exercise, and for long term exercise?
Skeletal Muscle Energy Metabolism
Three substrates to generate ATP:
- Creatine phosphate
- Glucose (via glycolysis and oxidative phosphorylation)
- Fatty acids (via oxidative phosphorylation)
- Amino acids but only used when you are in a catabolic state (usually not used to
generate ATP)
, Which energy source does skeletal muscle use during exercise?
Short sprint running→ ATP-PC system
As long as oxygen can be transported to the muscles→ aerobic system goes on