Inhoud
Polyarteritis nodosa ............................................................................................................................... 4
Ziekte van Kawasaki ............................................................................................................................... 4
Henoch-Schönlein .................................................................................................................................. 4
Hypersensitiviteit vasculitis .................................................................................................................... 5
Cryoglobulinemie ................................................................................................................................... 5
Guillain-Barré syndroom ........................................................................................................................ 6
Endocarditis ........................................................................................................................................... 7
Syndroom van Sjögren ........................................................................................................................... 8
Systemische Lupus Erythematodes ........................................................................................................ 8
Granulomatosis met polyangiitis (GPA) = Ziekte van Wegener .............................................................. 9
Acute bacteriële meningitis .................................................................................................................... 9
Subacute meningo-encefalitis .............................................................................................................. 10
Acute virale meningitis ......................................................................................................................... 10
Virale encefalitis ................................................................................................................................... 10
Abces in CZS ......................................................................................................................................... 10
Pneumonie ........................................................................................................................................... 10
Pneumocystis jirovecii pneumonie (PJP) .............................................................................................. 12
HIV........................................................................................................................................................ 12
Sarcoïdose (ziekte van Besnier-Boeck) ................................................................................................. 13
Syndroom van Löfgren ......................................................................................................................... 14
Antifosfolipiden syndroom (APS of APLS) ............................................................................................. 14
Cystic fibrosis ....................................................................................................................................... 15
Bronchiolitis (bij kinderen) ................................................................................................................... 16
Lagere luchtweginfectie ....................................................................................................................... 17
Huidaandoeningen ............................................................................................................................... 17
Epidermolysis bullosa (EB) ................................................................................................................... 18
Netherton syndroom ............................................................................................................................ 18
Vitiligo .................................................................................................................................................. 19
Psoriasis ............................................................................................................................................... 19
Atopisch eczeem .................................................................................................................................. 19
Malassezia ............................................................................................................................................ 19
Exantheem bij kinderen ....................................................................................................................... 19
1e ziekte: Mazelen (Morbilli) ................................................................................................................ 20
2e ziekte: Roodvonk .............................................................................................................................. 20
,3e ziekte: Rubella/Rode hond ............................................................................................................... 21
5e ziekte: Erythema infectiosum ........................................................................................................... 21
6e ziekte: Exanthema subitum .............................................................................................................. 22
Varicella (waterpokken) ....................................................................................................................... 22
Ziekte van Behçet ................................................................................................................................. 23
Systemische sclerose/sclerodermie ..................................................................................................... 23
Infectieziekten van de huid .................................................................................................................. 24
Ziekte van Lyme / Borreliose ................................................................................................................ 30
Reizigers- en importziekten .................................................................................................................. 31
Rabiës ................................................................................................................................................... 32
Koorts na de reis .................................................................................................................................. 32
Malaria ................................................................................................................................................. 32
Dengue ................................................................................................................................................. 33
Diarree na de reis ................................................................................................................................. 34
Campylobacter ..................................................................................................................................... 35
Amoebendysenterie ............................................................................................................................. 35
Giardiasis .............................................................................................................................................. 36
Huidklachten na de reis ........................................................................................................................ 36
Myasis (vliegenlarven) .......................................................................................................................... 37
Cutana larva migrans ............................................................................................................................ 37
Tunga penetrans (tungiasis) ................................................................................................................. 37
Ziekte van Lime/fyto-fotodermatitis .................................................................................................... 37
Cutane leishmania ................................................................................................................................ 38
Hepatitis ............................................................................................................................................... 38
Hepatitis A ............................................................................................................................................ 38
Hepatitis C ............................................................................................................................................ 39
Worminfecties ...................................................................................................................................... 39
Aarsmade ............................................................................................................................................. 40
Schistosomiasis .................................................................................................................................... 40
Ascaris lumbricoïdes............................................................................................................................. 41
Strongyloïdes stercoralis ...................................................................................................................... 42
Allergieën ............................................................................................................................................. 42
Type 1 allergie – IgE gemedieerd ......................................................................................................... 43
Acute urticaria (galbulten) ................................................................................................................... 44
Type II allergie ...................................................................................................................................... 44
Type III allergie ..................................................................................................................................... 44
,Type IV allergie – vertraagd beloop ...................................................................................................... 44
Atopisch syndroom .............................................................................................................................. 44
Constitutioneel eczeem ........................................................................................................................ 45
Voedsel allergie .................................................................................................................................... 46
Anafylaxie ............................................................................................................................................. 47
Beroepsallergie .................................................................................................................................... 49
Antibiotica ............................................................................................................................................ 50
Resistentie β-lactam antibiotica ........................................................................................................... 50
Preventie ziekenhuis infecties .............................................................................................................. 50
, Polyarteritis nodosa
Middelgrote vaten vasculitis (huid, zenuwen, tractus digestivus en hart)
Aspecifiek begin (grieperig)
Associatie met HepB infectie
Gemarmerde huid
Pijn na het eten
T: prednison en cyclofosfamide
Ziekte van Kawasaki
Middelgrote vaten vasculitis.
Kinderen 3 à 4 jaar.
Aardbeientong, kwijlen en rode huid.
Ontsteking coronairvaten.
T: immunoglobulines iv en aspirine (hart betrokkenheid)
Henoch-Schönlein
Kleine vaten vasculitis.
IgA complexen slaan neer in huid (benen). Meestal na infectie.
Purpura (>4mm)/petechiën(<4mm). Buikklachten, nierproblemen (bloedingen).
T: gaat vanzelf over
Meestal kinderen (<9 jaar).
Polyarteritis nodosa ............................................................................................................................... 4
Ziekte van Kawasaki ............................................................................................................................... 4
Henoch-Schönlein .................................................................................................................................. 4
Hypersensitiviteit vasculitis .................................................................................................................... 5
Cryoglobulinemie ................................................................................................................................... 5
Guillain-Barré syndroom ........................................................................................................................ 6
Endocarditis ........................................................................................................................................... 7
Syndroom van Sjögren ........................................................................................................................... 8
Systemische Lupus Erythematodes ........................................................................................................ 8
Granulomatosis met polyangiitis (GPA) = Ziekte van Wegener .............................................................. 9
Acute bacteriële meningitis .................................................................................................................... 9
Subacute meningo-encefalitis .............................................................................................................. 10
Acute virale meningitis ......................................................................................................................... 10
Virale encefalitis ................................................................................................................................... 10
Abces in CZS ......................................................................................................................................... 10
Pneumonie ........................................................................................................................................... 10
Pneumocystis jirovecii pneumonie (PJP) .............................................................................................. 12
HIV........................................................................................................................................................ 12
Sarcoïdose (ziekte van Besnier-Boeck) ................................................................................................. 13
Syndroom van Löfgren ......................................................................................................................... 14
Antifosfolipiden syndroom (APS of APLS) ............................................................................................. 14
Cystic fibrosis ....................................................................................................................................... 15
Bronchiolitis (bij kinderen) ................................................................................................................... 16
Lagere luchtweginfectie ....................................................................................................................... 17
Huidaandoeningen ............................................................................................................................... 17
Epidermolysis bullosa (EB) ................................................................................................................... 18
Netherton syndroom ............................................................................................................................ 18
Vitiligo .................................................................................................................................................. 19
Psoriasis ............................................................................................................................................... 19
Atopisch eczeem .................................................................................................................................. 19
Malassezia ............................................................................................................................................ 19
Exantheem bij kinderen ....................................................................................................................... 19
1e ziekte: Mazelen (Morbilli) ................................................................................................................ 20
2e ziekte: Roodvonk .............................................................................................................................. 20
,3e ziekte: Rubella/Rode hond ............................................................................................................... 21
5e ziekte: Erythema infectiosum ........................................................................................................... 21
6e ziekte: Exanthema subitum .............................................................................................................. 22
Varicella (waterpokken) ....................................................................................................................... 22
Ziekte van Behçet ................................................................................................................................. 23
Systemische sclerose/sclerodermie ..................................................................................................... 23
Infectieziekten van de huid .................................................................................................................. 24
Ziekte van Lyme / Borreliose ................................................................................................................ 30
Reizigers- en importziekten .................................................................................................................. 31
Rabiës ................................................................................................................................................... 32
Koorts na de reis .................................................................................................................................. 32
Malaria ................................................................................................................................................. 32
Dengue ................................................................................................................................................. 33
Diarree na de reis ................................................................................................................................. 34
Campylobacter ..................................................................................................................................... 35
Amoebendysenterie ............................................................................................................................. 35
Giardiasis .............................................................................................................................................. 36
Huidklachten na de reis ........................................................................................................................ 36
Myasis (vliegenlarven) .......................................................................................................................... 37
Cutana larva migrans ............................................................................................................................ 37
Tunga penetrans (tungiasis) ................................................................................................................. 37
Ziekte van Lime/fyto-fotodermatitis .................................................................................................... 37
Cutane leishmania ................................................................................................................................ 38
Hepatitis ............................................................................................................................................... 38
Hepatitis A ............................................................................................................................................ 38
Hepatitis C ............................................................................................................................................ 39
Worminfecties ...................................................................................................................................... 39
Aarsmade ............................................................................................................................................. 40
Schistosomiasis .................................................................................................................................... 40
Ascaris lumbricoïdes............................................................................................................................. 41
Strongyloïdes stercoralis ...................................................................................................................... 42
Allergieën ............................................................................................................................................. 42
Type 1 allergie – IgE gemedieerd ......................................................................................................... 43
Acute urticaria (galbulten) ................................................................................................................... 44
Type II allergie ...................................................................................................................................... 44
Type III allergie ..................................................................................................................................... 44
,Type IV allergie – vertraagd beloop ...................................................................................................... 44
Atopisch syndroom .............................................................................................................................. 44
Constitutioneel eczeem ........................................................................................................................ 45
Voedsel allergie .................................................................................................................................... 46
Anafylaxie ............................................................................................................................................. 47
Beroepsallergie .................................................................................................................................... 49
Antibiotica ............................................................................................................................................ 50
Resistentie β-lactam antibiotica ........................................................................................................... 50
Preventie ziekenhuis infecties .............................................................................................................. 50
, Polyarteritis nodosa
Middelgrote vaten vasculitis (huid, zenuwen, tractus digestivus en hart)
Aspecifiek begin (grieperig)
Associatie met HepB infectie
Gemarmerde huid
Pijn na het eten
T: prednison en cyclofosfamide
Ziekte van Kawasaki
Middelgrote vaten vasculitis.
Kinderen 3 à 4 jaar.
Aardbeientong, kwijlen en rode huid.
Ontsteking coronairvaten.
T: immunoglobulines iv en aspirine (hart betrokkenheid)
Henoch-Schönlein
Kleine vaten vasculitis.
IgA complexen slaan neer in huid (benen). Meestal na infectie.
Purpura (>4mm)/petechiën(<4mm). Buikklachten, nierproblemen (bloedingen).
T: gaat vanzelf over
Meestal kinderen (<9 jaar).
