Cell Division
Semiconservative DNA replication
leading strand new (daughter)
5' ~
tt•
t~ ~
~\\JJ ~ 'IUlP I ,i
...
st
r:~:1e-strand
b1nd1ng proteins
~ JWI " 3, ~ L /ep~i:ion 3,
3
' DNA polymerase( helicase ' ; ~ ~.;•111,rlM I
DNA ligase \
\ _
5
"- "\,. 't ,ifJ -.UJ/'1 . 5'
• r.,, ,:____
old (parent)
strand
·
'. "'-- 0 k a z a k i fragment
I (
3'
lagging strand
~.;i 2 013 En cyc lopredia Brllnnnic::i , Inc . 1
, THE C
ttl CYC l t
A \u g_h, ~ o,d~tt_d . seque nc.e r-1uc~ toker plu CJl in u ce I!
~v~nts
o.nd rtSu\ts ,n tu ojvi ~i on c~ tk ce\l, ~oon, ri% 2 i~ (\ n:ic~
iQ~Dl1rn I d0113-htu CR\\ ~
1hft-t C\ ti' l m()j(\ phasrs ( in ~u Ka~otic Ctl I~) ~
'N TlRPl~A SE-
The cell · double chedtS" the
dupl.ca\ed chromosomes for t he r[Wh1 . pc.n-od C/L(J 1/\.,1(_~ I
A /
cfT'O(, making llflY oeetie<J .• . 0. 11 cs penc\ s
Mitosis .... ·'i \ .
I moH 1 ,ts b' mt ,n tlir
rei:,a1rs.
c~11 ~•tr inci-tcuo .A. • '
01\Jf\ 11 chtck.ru:;;. - - , ¢016~ ~ \,\ ~ht\~l
G1 I "'e tu
s "0~~ ce,1 \i1e ioot 1 ph<He r1he~
.X~ Each of rhe 46 eel\ eitlR r t('.rnporu.n·1g
· (hrori•,050rfl,CS •·• · Ce ll ula r cor1teot:;,
, auph~t~o 'b•; the ello uo,ng r,he chrornosomcs , or perm ctn en t I~ \ t,qm
c<dlL '"' Q"iJ A arPu d upl1cill~ -
l'f t)lit ll.bCJr\ prottif\ ~~nthWr
tu ve II c.w,1~
O(CU r\ Whil '1,\ / '-.. t\.R. ~ tl hoc
mo u t Go ~u l)NA d d,j~(t·n'ltiottcl
Cell cycle arres• I\ (lfriO~
The G-1 ch rcKQOint occun a.t the end fu G1 phcue
th
cell siu, nutn ef'ts ts DNA dafY"a~ OI-{ au ecKed
tl.e. & phase , {QC'\1 DNA rno\ecu1e ( chrom.o~ome}
Dun·o_g
i~ con\Jtrr td info 2 i dtnt i c..oJ DN f\ mo,~cu\~ r C(h'romuod ~)
DNA r Omb I·ne, v-rifl - Iu sto:ou to ~rm ad em~ / ,r=,-;=;-. Sister chromat·!ls I
Sisklrchrnma~ds
. ,__c:;--7....L-,
ClHYlPl(''t ca.lle_.d ch rp mot; A r
Toe Lt a rt ,q\11nw OJ'
<l 1<.ept to%ether tu (tnuomer<:
So t u. ~ c.an be prec,q l~
mnocry vrt.d arid sepa rn t t-d . • .. 'I'tJ!: Replication
.,
~9,U o.l~
'
lhe G,. cbtckPOJot occurs
ot th~ ~nd tu C':r2. phase
chects J-or QN-A Kornai)ga'JS
Homologous
dOmo~ and Df\l A rt.pli cA ti c""
chromosoire 1
momosomes
Chee ts Gell ~11e
The cell ir \ U\tHen t ~ hrn \t ha, ..lllll. thr obi lit~ to &XJZkl o.,n d
dJ vid t '6 c:;.o ~nttY\ t\..Q Go \)nU\~
Semiconservative DNA replication
leading strand new (daughter)
5' ~
tt•
t~ ~
~\\JJ ~ 'IUlP I ,i
...
st
r:~:1e-strand
b1nd1ng proteins
~ JWI " 3, ~ L /ep~i:ion 3,
3
' DNA polymerase( helicase ' ; ~ ~.;•111,rlM I
DNA ligase \
\ _
5
"- "\,. 't ,ifJ -.UJ/'1 . 5'
• r.,, ,:____
old (parent)
strand
·
'. "'-- 0 k a z a k i fragment
I (
3'
lagging strand
~.;i 2 013 En cyc lopredia Brllnnnic::i , Inc . 1
, THE C
ttl CYC l t
A \u g_h, ~ o,d~tt_d . seque nc.e r-1uc~ toker plu CJl in u ce I!
~v~nts
o.nd rtSu\ts ,n tu ojvi ~i on c~ tk ce\l, ~oon, ri% 2 i~ (\ n:ic~
iQ~Dl1rn I d0113-htu CR\\ ~
1hft-t C\ ti' l m()j(\ phasrs ( in ~u Ka~otic Ctl I~) ~
'N TlRPl~A SE-
The cell · double chedtS" the
dupl.ca\ed chromosomes for t he r[Wh1 . pc.n-od C/L(J 1/\.,1(_~ I
A /
cfT'O(, making llflY oeetie<J .• . 0. 11 cs penc\ s
Mitosis .... ·'i \ .
I moH 1 ,ts b' mt ,n tlir
rei:,a1rs.
c~11 ~•tr inci-tcuo .A. • '
01\Jf\ 11 chtck.ru:;;. - - , ¢016~ ~ \,\ ~ht\~l
G1 I "'e tu
s "0~~ ce,1 \i1e ioot 1 ph<He r1he~
.X~ Each of rhe 46 eel\ eitlR r t('.rnporu.n·1g
· (hrori•,050rfl,CS •·• · Ce ll ula r cor1teot:;,
, auph~t~o 'b•; the ello uo,ng r,he chrornosomcs , or perm ctn en t I~ \ t,qm
c<dlL '"' Q"iJ A arPu d upl1cill~ -
l'f t)lit ll.bCJr\ prottif\ ~~nthWr
tu ve II c.w,1~
O(CU r\ Whil '1,\ / '-.. t\.R. ~ tl hoc
mo u t Go ~u l)NA d d,j~(t·n'ltiottcl
Cell cycle arres• I\ (lfriO~
The G-1 ch rcKQOint occun a.t the end fu G1 phcue
th
cell siu, nutn ef'ts ts DNA dafY"a~ OI-{ au ecKed
tl.e. & phase , {QC'\1 DNA rno\ecu1e ( chrom.o~ome}
Dun·o_g
i~ con\Jtrr td info 2 i dtnt i c..oJ DN f\ mo,~cu\~ r C(h'romuod ~)
DNA r Omb I·ne, v-rifl - Iu sto:ou to ~rm ad em~ / ,r=,-;=;-. Sister chromat·!ls I
Sisklrchrnma~ds
. ,__c:;--7....L-,
ClHYlPl(''t ca.lle_.d ch rp mot; A r
Toe Lt a rt ,q\11nw OJ'
<l 1<.ept to%ether tu (tnuomer<:
So t u. ~ c.an be prec,q l~
mnocry vrt.d arid sepa rn t t-d . • .. 'I'tJ!: Replication
.,
~9,U o.l~
'
lhe G,. cbtckPOJot occurs
ot th~ ~nd tu C':r2. phase
chects J-or QN-A Kornai)ga'JS
Homologous
dOmo~ and Df\l A rt.pli cA ti c""
chromosoire 1
momosomes
Chee ts Gell ~11e
The cell ir \ U\tHen t ~ hrn \t ha, ..lllll. thr obi lit~ to &XJZkl o.,n d
dJ vid t '6 c:;.o ~nttY\ t\..Q Go \)nU\~
