Practice Questions and Correct Answers 2026/2027
1. What is the role of mast cells in the immune response?
Mast cells release granzymes that create pores between endothelial
cells and facilitate leukocytes to the site of infection.
Mast cells are a type of phagocyte that recognizes PAMPs on
pathogens.
Mast cells release complement proteins which form a membrane
attack complex on the pathogen.
Mast cells release histamine which facilitates the movement of
leukocytes to the site of infection.
2. Which of the following sets of clinical manifestations is most characteristic of
influenza?
body aches, cough, sore throat
nasal congestion, sneezing, watery eyes
headache, sinus pressure, fever
diarrhea, stomach cramping, vomiting
3. Describe the relationship between liver disease and the risk of bleeding.
Liver disease has no impact on bleeding risk.
Liver disease enhances the production of clotting factors, reducing
the risk of bleeding.
Liver disease causes the body to produce more platelets, increasing
bleeding risk.
, Liver disease leads to impaired production of clotting factors, which
increases the risk of bleeding.
4. What is the main purpose of the fibrin mesh formed during the coagulation
cascade?
To stop bleeding and trap microorganisms
To promote inflammation
To enhance antibody production
To facilitate cell division
5. Describe the relationship between the antigens and antibodies present in
blood type A.
Blood type A has A antigens on the surface of red blood cells and
produces B antibodies in the plasma.
Blood type A has B antigens and produces A antibodies.
Blood type A has A antigens and produces O antibodies.
Blood type A has no antigens and produces AB antibodies.
6. This involves immune complexes that are formed when the antigens bind to
antibodies, immune complexes are then deposited in tissues or vascular
endothelium
Delayed-Type hypersensitivity
Cytotoxic
Anaphylactic
Immune Complex
,7. In a patient experiencing an allergic reaction, what role do mast cells play in
the symptoms observed?
They inhibit the activity of other immune cells.
They produce antibodies that neutralize allergens.
They directly kill pathogens in the bloodstream.
They release granules that cause inflammation and allergic
symptoms.
8. If a person with blood type A receives blood from a type B donor, what
immune response is likely to occur?
A transfusion reaction due to the presence of A antibodies.
A transfusion reaction due to the presence of B antibodies.
No reaction as the blood types are compatible.
A mild immune response with no serious consequences.
9. Describe the role of intrinsic factor in the development of pernicious anemia.
Intrinsic factor is responsible for the maturation of white blood cells,
and its lack causes leukopenia.
Intrinsic factor is involved in iron absorption, and its deficiency leads
to iron-deficiency anemia.
Intrinsic factor helps in the production of hemoglobin, and its absence
causes low hemoglobin levels.
Intrinsic factor is necessary for the absorption of Vitamin B12, and its
absence leads to Vitamin B12 deficiency and subsequent anemia.
10. What is the most common cause of microcytic anemia?
, Iron deficiency anemia (IDA)
Hemolytic anemia
Folic acid deficiency
Vitamin B12 deficiency
11. What is the definition of leukopenia?
An increase in red blood cells
A decrease in the total white blood cell count
A type of autoimmune disease
A condition affecting hemoglobin levels
12. How to treat autoimmune diseases?
symptomatic treatment
immunosuppressants inhibit the immune system
anti-inflammatory drugs can help
all three are true
13. In a patient with a bleeding disorder, how might thromboxane levels affect
their condition?
Thromboxane levels would have no effect on bleeding disorders.
High thromboxane levels would enhance platelet aggregation and
reduce bleeding.
Low thromboxane levels could lead to impaired platelet
aggregation and increased bleeding.
Thromboxane would only affect blood pressure, not bleeding.