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Lecture Notes Risk Behavior and Addiction | Adolescence | Utrecht | 2025/26

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Lecture notes from the introductory session of Risk Behavior and Addiction in Adolescence () at Universiteit Utrecht. Covers definitions of risk behavior and addiction, neurological development during adolescence, brain region development differences, and the Behavior Change Wheel model for intervention planning. Essential for understanding the course framework and the neuroscientific basis of adolescent risk-taking, with practical applications for behavior change diagnosis and intervention strategies.

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NOTES LECTURES RISK BEHAVIOR AND ADDICTION IN ADOLESCENCE



Lecture 1 – 4/9: Introduction Risk Behavior and Addiction in
Adolescence
How do we define Risk Behaviour?
Risk Behaviour
- Risk Behaviour: Behaviours that pose a risk to a healthy physical, cognitive,
psychosocial development of adolescents
 Substance use (e.g., smoking/vaping, alcohol use, cannabis use, use of XTC
and other party/designer drugs)
 Other risk behaviors (e.g., (online) gambling, gaming, social media use)
- Addiction

The general development process of addiction
Contact with a substance  Experimenting with a substance  Integrated use (part of
daily life)  Excessive use (higher proportions)  Addicted use

Something can become a risk behavior when it becomes excessive
 Nicotine addiction can develop on very early on, when someone is in a position to start
with smoking

What we tend to regard as ‘risks behavior’ depends on…
- Characteristics of the particular substance or behavior
 For instance, smoking/vaping versus gaming
- Cultural and societal norms: what is seen as risk behavior
 Example: alcohol use in western versus Islamic cultures
- Advances in scientific knowledge:
 Example: knowledge on the risks of alcohol use for the development of the
adolescent brain

Predictors of Risk Behavior
(Risk) behaviors
depend on
three things:
capability,
motivation,
opportunity




 The Behavior Change
Wheel
(will be central later on)

Which (neurological) developments take place during adolescence?
Adolescence (+10 – 24 years)
- Early adolescence (aged 10 – 14): physical growth, sexual maturation, psychosocial
development, social identity formation (who am I in the eyes of my peers)
- Mid adolescence (aged 15 – 17): experimenting with (risk) behaviours, personal
identity formation (who am I through my own eyes)
- Late adolescence (aged 18 – 24): practicing adult roles

Neurological development in adolescence
1. Strong grow in brain volume

, NOTES LECTURES RISK BEHAVIOR AND ADDICTION IN ADOLESCENCE


 Decrease in grey matter (nerve cells)
 Increase in white matter (connections –
brain and cells)
 Decrease starts age 11 girls, age 14 boys
 Not all parts grey matter is decreasing  Pruning (snoeien); depends on which
parts of the grey matters is used, the parts who are less used will disappear –
if you don’t use it, you lose it
2. High plasticity and flexibility of the brain
 Phones  no sustains attention – through flexibility certain skills can be trained
again and you can gain it again
3. Increase in white matter: communication between brain regions strongly
improves
 Long term memory increases
 Capacity for abstract (critical) thinking and
metacognition increases
 This development certainly results in conflicts
between child and parents
 All smaller roads are disappearing, but bigger
stronger roads will appear

Why is there a peak in risk behaviours during adolescence?
Risk behavior follows an inverted U-shaped curve




Neurological development in adolescence
- The speed of the development of two different brain
regions differs
 The affective-motivational system
(emotional brain) develops fast
 the VTA produces dopamine and
sends it to the nucleus accumbens,
thereby creating feelings of reward
 Old part of the brain
 Part plays an important role regarding
rewards and motivation
 Is overactive during early and mid-
adolescence
 Adolescents experience stronger
positive emotions than adults when they receive or anticipate a
reward  process is enhanced by testosterone
 Boys: generally higher testosterone, they tend to show more risk
behavior
 The control system (rational brain) develops slowly
 Outside of the brain

, NOTES LECTURES RISK BEHAVIOR AND ADDICTION IN ADOLESCENCE


 Develops very slowly (until about 25 years)
 Plays important role in the development of executive functions:
 Risk estimations
 Monitoring long-term goals
 Inhibition of the tendency to respond to (short-term) possibilities
for reward (impulse control, behavioral inhibition, self-control)
 Systems interact

The Maturational Imbalance Model
- Increased risk-taking during adolescence is
a result of an imbalance between reward
sensitivity (the affective-motivational
system) and impulse control (control
system)
- Risk taking during adolescence is result of
an imbalance

The horse and rider metaphor
- Rider: Control system; keep it in control
– top-down processes, behavioral
inhabitation system (BIS)
- Horse: Motivational system; wants to
run – bottom-up processes, behavioral
activation system (BAS)




What are psycho-active substances
(drugs)?
How can we define drugs or psycho-active substances?
- Psychoactive substances are chemical substances that cross the blood-brain
barrier and affect the function of the central nervous system thereby changing mood,
perceptions, or consciousness (e.g., high/ euphoria, relaxation)
- Other characteristics of psychoactive substances:
 They often induce craving after (regular) use
 They often evoke loss of control after they have been used (regularly)

Psychoactive substances differ in…
- Type and strength of the psychoactive effect
- The degree to which they elicit craving and loss of control

For which substance is the risk highest to develop addiction after one has used the
substance only once? NICOTINE!

Types of drugs (based on their psychoactive effects)

, NOTES LECTURES RISK BEHAVIOR AND ADDICTION IN ADOLESCENCE




How do we define Addiction?
- Intensional: these definitions aim to describe a causal addiction process (see
Sussman, Table 1.2)
- Extensional: a classification of characteristics of an addiction (e.g. DSM-5, ICD-11)

Substance use disorder (DSM-5 TR, 2022)
- Classification system: you are defined as addicted if you have certain criteria
- Recurrent use over the last 12 months AND meeting at least two or more criteria (2-3
mild, 4-5 moderate, 6> severe SUD)




Which implicit/automatic processes underlie the development of
addiction?
Two learning principles underlying the development of addiction
1. Positive reinforcement occurs when the rate of a behavior increases because a
desirable experience (e.g., euphoria, relaxation) is resulting from the behavior
2. Negative reinforcement occurs when the rate of a behavior increases because an
aversive experience is prevented from happening (e.g., withdrawal symptoms)

The neurobiological of withdrawal symptoms?
VIDEO LECTURE 1 –
https://www.youtube.com/ watch?
v=NxHNxmJv2bQ (EXAM MATERIAL)

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