PCM III- Inflammation & Repair Exam Questions with Correct
Answers (Grade A+)
Question 1: goal of inflammation & repair
Answer: restore function by eliminating pathological or physical insult replace damaged/destroyed tissue
promote regeneration of normal tissue structure
Question 2: 3 stages of healing
Answer: inflammation proliferation maturation/remodeling
Question 3: inflammation phase
Answer: prepares wound for healing (1-6 days)
Question 4: proliferation phase
Answer: rebuild damaged structures and strengthens wound (3-20 days)
Question 5: maturation/remodeling phase
Answer: modifies scar tissue into mature form (day 9-recovery)
Question 6: stages of inflammation phase
Answer: vascular hemostatic cellular immune
Question 7: goal of inflammation phase
Answer: form fibrin lattice to limit blood loss and provide strength to the wound prepare wound for healing
by removing damaged tissue and recruiting endothelial cells and fibroblasts
Question 8: inflammation phase cardinal signs
Answer: heat erythema edema pain loss of function
Question 9: why does heat occur
Answer: vasodilation and increased BF
Question 10: why does erythema occur
Page 1
, Answer: vasodilation and increased BF
Question 11: why does edema occur
Answer: fluid and cells leaking from BV due to increased permeability and vasodilation blockage of
lymphatic drainage
Question 12: why does pain occur
Answer: pressure or chemical irritation of nociceptive nerve endings
Question 13: why does loss of function occur
Answer: caused by tissue disruption, pain, and muscle inhibition
Question 14: first stage of inflammation vascular response
Answer: transient vasoconstriction to minimize blood loss 5-10 min
Question 15: what causes transient vasoconstriction
Answer: norepinephrine and serotonin
Question 16: what happens to BV after vasoconstriction
Answer: vasodilation to being blood and other components related to healing to the site of injury capillary
permeability is increased, more fluid leaks out
Question 17: what causes vasodilation and capillary permeability
Answer: histamine Hageman factor bradykinin prostaglandins complenet fractions
Question 18: effect of prostaglandins
Answer: attract leukocytes sensitize nociceptive fibers (increasing peripheral sensitivity)
Question 19: transudate
Answer: first liquid to leak out mostly water, little protein or cells
Question 20: exudate
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Answers (Grade A+)
Question 1: goal of inflammation & repair
Answer: restore function by eliminating pathological or physical insult replace damaged/destroyed tissue
promote regeneration of normal tissue structure
Question 2: 3 stages of healing
Answer: inflammation proliferation maturation/remodeling
Question 3: inflammation phase
Answer: prepares wound for healing (1-6 days)
Question 4: proliferation phase
Answer: rebuild damaged structures and strengthens wound (3-20 days)
Question 5: maturation/remodeling phase
Answer: modifies scar tissue into mature form (day 9-recovery)
Question 6: stages of inflammation phase
Answer: vascular hemostatic cellular immune
Question 7: goal of inflammation phase
Answer: form fibrin lattice to limit blood loss and provide strength to the wound prepare wound for healing
by removing damaged tissue and recruiting endothelial cells and fibroblasts
Question 8: inflammation phase cardinal signs
Answer: heat erythema edema pain loss of function
Question 9: why does heat occur
Answer: vasodilation and increased BF
Question 10: why does erythema occur
Page 1
, Answer: vasodilation and increased BF
Question 11: why does edema occur
Answer: fluid and cells leaking from BV due to increased permeability and vasodilation blockage of
lymphatic drainage
Question 12: why does pain occur
Answer: pressure or chemical irritation of nociceptive nerve endings
Question 13: why does loss of function occur
Answer: caused by tissue disruption, pain, and muscle inhibition
Question 14: first stage of inflammation vascular response
Answer: transient vasoconstriction to minimize blood loss 5-10 min
Question 15: what causes transient vasoconstriction
Answer: norepinephrine and serotonin
Question 16: what happens to BV after vasoconstriction
Answer: vasodilation to being blood and other components related to healing to the site of injury capillary
permeability is increased, more fluid leaks out
Question 17: what causes vasodilation and capillary permeability
Answer: histamine Hageman factor bradykinin prostaglandins complenet fractions
Question 18: effect of prostaglandins
Answer: attract leukocytes sensitize nociceptive fibers (increasing peripheral sensitivity)
Question 19: transudate
Answer: first liquid to leak out mostly water, little protein or cells
Question 20: exudate
Page 2