BIO
BIO
302
BIO
302
Cancer
302
Cancer
Cancer
ASU
ASU
ASU
Exam
Exam
Exam
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
BIO 302 Cancer ASU Exam 1 Cancer ASU Exam 1
BIO 302
Study online at https://quizlet.com/_3pzgjb
1. The fundamental cause of cancer is gene T
mutation. T/F
2. Only malignant neoplasms can cause death. F
T/F
3. Carcinogenesis is the process by which can- F
cer cells spread throughout the body. T/F
4. Most cancers start as benign neoplasms. T/F F
5. Dysplastic cells are precursors to cancer. T/F T
6. How many women will develop cancer in 1 out of every 3
their lifetime?
7. How many men will develop cancer in their 1 out of every 2
lifetime
8. Cancer cells arise from normal cells and uti- T
lize normal processes in abnormal ways. T/F
9. All cancers have the common feature: loss of T
growth control. T/F
10. Not all tumors are cancer. T/F T
11. Gain of function mutations in cancer impact Oncogenes
which class of genes?
12. Cancer will undergo high rates of glycolysis T
and produce large amounts of lactic acid
regardless of oxygen availability. T/F
13. Primary somatic cells
1
BIO
BIO
302
BIO
302
Cancer
302
Cancer
Cancer
ASU
ASU
ASU
Exam
Exam
Exam
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
, BIO
BIO
302
BIO
302
Cancer
302
Cancer
Cancer
ASU
ASU
ASU
Exam
Exam
Exam
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
BIO 302 Cancer ASU Exam 1 Cancer ASU Exam 1
BIO 302
Study online at https://quizlet.com/_3pzgjb
Telomere length can be maintained by all of
the following cell types, EXCEPT:
14. Changes in tumor-suppressor gene expres- epigenetic silencing
sion without mutating or altering the DNA
sequence in referred to as ______________.
15. What is carcinogenesis? The process by which normal cells trans-
form into cancer cells.
16. p53 is a commonly altered ______________ in tumor suppressor gene
many cancers.
17. Which of the following molecular changes All of the above.
can allow cancer cells to avoid cell death?
mutations in p53
increased telomerase expression
decreased expression of caspases
All of the above.
18. It is possible to block the action of onco- T
genes with drugs.
T/F
19. What are two main categories of tumor sup- gatekeepers and caretakers
pressor genes that can be altered in cancer?
20. Loss of function mutations impact which tumor suppressors
class of genes?
2
BIO
BIO
302
BIO
302
Cancer
302
Cancer
Cancer
ASU
ASU
ASU
Exam
Exam
Exam
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
, BIO
BIO
302
BIO
302
Cancer
302
Cancer
Cancer
ASU
ASU
ASU
Exam
Exam
Exam
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
BIO 302 Cancer ASU Exam 1 Cancer ASU Exam 1
BIO 302
Study online at https://quizlet.com/_3pzgjb
21. Consequences of leaky, chaotic tumor blood Increased inflammation in the microenvi-
vessels? ronment.
Impaired drug delivery to the tumor.
Facilitation of invasion and metastasis.
22. Process of tumor metastasis. 1. primary tumor formation
2. local invasion
3. intravasation
4. survival in circulation
5. extravasation
6. micrometastasis formation
7. metastatic colonization and tumor
growth
8. clinically detectable macroscopic
metastasis
23. Tumor metastasis step 1of8: primary tumor formation
24. Tumor metastasis step 2of8: local invasion
25. Tumor metastasis step 3of8: intravasation
26. Tumor metastasis step 4of8: survival in circulation
27. Tumor metastasis step 5of8: extravasation
3
BIO
BIO
302
BIO
302
Cancer
302
Cancer
Cancer
ASU
ASU
ASU
Exam
Exam
Exam
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
BIO
302
BIO
302
Cancer
302
Cancer
Cancer
ASU
ASU
ASU
Exam
Exam
Exam
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
BIO 302 Cancer ASU Exam 1 Cancer ASU Exam 1
BIO 302
Study online at https://quizlet.com/_3pzgjb
1. The fundamental cause of cancer is gene T
mutation. T/F
2. Only malignant neoplasms can cause death. F
T/F
3. Carcinogenesis is the process by which can- F
cer cells spread throughout the body. T/F
4. Most cancers start as benign neoplasms. T/F F
5. Dysplastic cells are precursors to cancer. T/F T
6. How many women will develop cancer in 1 out of every 3
their lifetime?
7. How many men will develop cancer in their 1 out of every 2
lifetime
8. Cancer cells arise from normal cells and uti- T
lize normal processes in abnormal ways. T/F
9. All cancers have the common feature: loss of T
growth control. T/F
10. Not all tumors are cancer. T/F T
11. Gain of function mutations in cancer impact Oncogenes
which class of genes?
12. Cancer will undergo high rates of glycolysis T
and produce large amounts of lactic acid
regardless of oxygen availability. T/F
13. Primary somatic cells
1
BIO
BIO
302
BIO
302
Cancer
302
Cancer
Cancer
ASU
ASU
ASU
Exam
Exam
Exam
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
, BIO
BIO
302
BIO
302
Cancer
302
Cancer
Cancer
ASU
ASU
ASU
Exam
Exam
Exam
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
BIO 302 Cancer ASU Exam 1 Cancer ASU Exam 1
BIO 302
Study online at https://quizlet.com/_3pzgjb
Telomere length can be maintained by all of
the following cell types, EXCEPT:
14. Changes in tumor-suppressor gene expres- epigenetic silencing
sion without mutating or altering the DNA
sequence in referred to as ______________.
15. What is carcinogenesis? The process by which normal cells trans-
form into cancer cells.
16. p53 is a commonly altered ______________ in tumor suppressor gene
many cancers.
17. Which of the following molecular changes All of the above.
can allow cancer cells to avoid cell death?
mutations in p53
increased telomerase expression
decreased expression of caspases
All of the above.
18. It is possible to block the action of onco- T
genes with drugs.
T/F
19. What are two main categories of tumor sup- gatekeepers and caretakers
pressor genes that can be altered in cancer?
20. Loss of function mutations impact which tumor suppressors
class of genes?
2
BIO
BIO
302
BIO
302
Cancer
302
Cancer
Cancer
ASU
ASU
ASU
Exam
Exam
Exam
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
, BIO
BIO
302
BIO
302
Cancer
302
Cancer
Cancer
ASU
ASU
ASU
Exam
Exam
Exam
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
BIO 302 Cancer ASU Exam 1 Cancer ASU Exam 1
BIO 302
Study online at https://quizlet.com/_3pzgjb
21. Consequences of leaky, chaotic tumor blood Increased inflammation in the microenvi-
vessels? ronment.
Impaired drug delivery to the tumor.
Facilitation of invasion and metastasis.
22. Process of tumor metastasis. 1. primary tumor formation
2. local invasion
3. intravasation
4. survival in circulation
5. extravasation
6. micrometastasis formation
7. metastatic colonization and tumor
growth
8. clinically detectable macroscopic
metastasis
23. Tumor metastasis step 1of8: primary tumor formation
24. Tumor metastasis step 2of8: local invasion
25. Tumor metastasis step 3of8: intravasation
26. Tumor metastasis step 4of8: survival in circulation
27. Tumor metastasis step 5of8: extravasation
3
BIO
BIO
302
BIO
302
Cancer
302
Cancer
Cancer
ASU
ASU
ASU
Exam
Exam
Exam
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
1.pdf!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~@@@@@@@@@@@@@@@@@@@@@@@@
