PATHOPHYSIOLOGY STUDY GUIDE
30+ Conditions with Dx, Pharm & Non-Pharm Tx
Based on McCance & Huether Textbook
★ 2026/2027 UPDATE ★
Subject: Pathophysiology / Advanced Pathophysiology
Level: Bachelor's / Master's Degree – Nursing
Year: 2026/2027
Author: Nursing Student
� CONDITIONS COVERED
✅Cardiovascular: HTN, Ischemic HD, CHF, HLHS
✅Endocrine: Hypothyroid, Thyroid Storm, Parathyroid
✅Hematological: Sickle Cell, Thalassemia, G6PD
✅Oncology: Lung CA, Medullary Thyroid CA
✅Neurological: Alzheimer's, Schizophrenia, MG
✅GI: Crohn's, Ulcerative Colitis
✅Renal: Nephritis
✅Infectious: TB/PPD, Strep Pharyngitis
✅Psychiatric: Generalized Anxiety Disorder
✅Genetic: Fragile X, Color Blindness
✅Metabolic: DKA
✅Lab Values: BUN, Creatinine, K+, Na+, TSH, PT/PTT, INR
✅Comprehensive Study Guide
✅Perfect for Pathophysiology Exams & Nursing Finals
, Pathophysiology Study Guide – Complete Review of 30+ Conditions | McCance &
Huether | Nursing & Medical Students | 2026/2027
CONDITION SUB. Hx. FINDINGS Dx PHARM Tx Non-PHARM Tx MISC.
Primary HTN • Sx rare until • increased BP r/t • Hx & physical • diuretics • lifestyle mods
HTN is severe • increased • BP • ACE • reduce sodium
peripheral • ambulatory • ARB
resistance monitoring • CCB
Ischemic Heart • crushing/ • hypoxia • EKG • daily aspirin • lifestyle mods • Complications =
Disease squeezing/sharp • arrhythmias • Holter • Beta blockers • HF, MI, stroke,
pain in nech/ • aFib monitoring • CCBs PAD
jaw/chest • ST elevation • cardiac cath • ACE
CHF • SOB • auscultation • ECG • ACE: enlapril, • coronary bypass • May lead to
• edema in ankles • heart murmur • ECHO lisinopril • implanted ICD heart transplant
aka & feet • JVD • stress test diuretics • implanted VAD
• rapid wt gain r/t • edema • CT • Digoxin
Heart Failure/HF fluid build-up assessment • MRI • ARB: losartan,
• rapid or irregular HR • coronary valsartan
• persistent cough angiogram • Beta Blockers:
or wheezing carvedilol,
metoprolol
Hypoplastic L • cyanosis • Foramen ovale & • prenatal US • aprostadil to • 3 stage surgery • May require
Heart Syndrome • poor feeding ductus • ECHO keep ductus to open ductus heart transplant.
• rapid dyspnea arteriosus will • heart murmur arteriosus & arteriosus &
close w/out foramen ovale foramen ovale
intervention open until
surgery
Pleural Effusion • chest pain • fluid build-up in • CXR • diuretics • chest tube to
• dry cough pleural space • CT • ABX drain fluid
• dyspnea • US of chest
Nephritis • proteinuria • urinalysis • Tx BP • reduce sodium, • Can be acute or
• hematuria • hyperalbuminemia • blood test r/t • diuretics protein & K+ chronic.
• decreased urine • hyperlipidemia kidney function • ACE • control BP • May lead to
• nocturia • ultrasound kidney failure.
30+ Conditions with Dx, Pharm & Non-Pharm Tx
Based on McCance & Huether Textbook
★ 2026/2027 UPDATE ★
Subject: Pathophysiology / Advanced Pathophysiology
Level: Bachelor's / Master's Degree – Nursing
Year: 2026/2027
Author: Nursing Student
� CONDITIONS COVERED
✅Cardiovascular: HTN, Ischemic HD, CHF, HLHS
✅Endocrine: Hypothyroid, Thyroid Storm, Parathyroid
✅Hematological: Sickle Cell, Thalassemia, G6PD
✅Oncology: Lung CA, Medullary Thyroid CA
✅Neurological: Alzheimer's, Schizophrenia, MG
✅GI: Crohn's, Ulcerative Colitis
✅Renal: Nephritis
✅Infectious: TB/PPD, Strep Pharyngitis
✅Psychiatric: Generalized Anxiety Disorder
✅Genetic: Fragile X, Color Blindness
✅Metabolic: DKA
✅Lab Values: BUN, Creatinine, K+, Na+, TSH, PT/PTT, INR
✅Comprehensive Study Guide
✅Perfect for Pathophysiology Exams & Nursing Finals
, Pathophysiology Study Guide – Complete Review of 30+ Conditions | McCance &
Huether | Nursing & Medical Students | 2026/2027
CONDITION SUB. Hx. FINDINGS Dx PHARM Tx Non-PHARM Tx MISC.
Primary HTN • Sx rare until • increased BP r/t • Hx & physical • diuretics • lifestyle mods
HTN is severe • increased • BP • ACE • reduce sodium
peripheral • ambulatory • ARB
resistance monitoring • CCB
Ischemic Heart • crushing/ • hypoxia • EKG • daily aspirin • lifestyle mods • Complications =
Disease squeezing/sharp • arrhythmias • Holter • Beta blockers • HF, MI, stroke,
pain in nech/ • aFib monitoring • CCBs PAD
jaw/chest • ST elevation • cardiac cath • ACE
CHF • SOB • auscultation • ECG • ACE: enlapril, • coronary bypass • May lead to
• edema in ankles • heart murmur • ECHO lisinopril • implanted ICD heart transplant
aka & feet • JVD • stress test diuretics • implanted VAD
• rapid wt gain r/t • edema • CT • Digoxin
Heart Failure/HF fluid build-up assessment • MRI • ARB: losartan,
• rapid or irregular HR • coronary valsartan
• persistent cough angiogram • Beta Blockers:
or wheezing carvedilol,
metoprolol
Hypoplastic L • cyanosis • Foramen ovale & • prenatal US • aprostadil to • 3 stage surgery • May require
Heart Syndrome • poor feeding ductus • ECHO keep ductus to open ductus heart transplant.
• rapid dyspnea arteriosus will • heart murmur arteriosus & arteriosus &
close w/out foramen ovale foramen ovale
intervention open until
surgery
Pleural Effusion • chest pain • fluid build-up in • CXR • diuretics • chest tube to
• dry cough pleural space • CT • ABX drain fluid
• dyspnea • US of chest
Nephritis • proteinuria • urinalysis • Tx BP • reduce sodium, • Can be acute or
• hematuria • hyperalbuminemia • blood test r/t • diuretics protein & K+ chronic.
• decreased urine • hyperlipidemia kidney function • ACE • control BP • May lead to
• nocturia • ultrasound kidney failure.
