MENDIX CERTIFICATION EXAM PREP
QUESTIONS AND ANSWERS FULL
SOLUTION GRADED A+
⩥ Mast cell.
Answer: Cellular bags of granules located in loose connective tisssue
close to blood vessels. Activation initiates inflammatory process.
⩥ Histamine.
Answer: Causes vasodilation, increases vascular permeability, increases
blood flow to the site of injury- causes erythema and swelling.
⩥ Cytokines.
Answer: Soluble factors that contribute to the regulation of innate or
adaptive resistance by affecting other neighboring cells. Can be pro-
inflammatory or anti-inflammatory. Can react quickly or be more
delayed.
⩥ Leukotrines.
Answer: Released when mast cells degranulate, prolong the
inflammatory process. Cause vasodilation, attract neutrophils,
monocytes, and eosinophils.target of inhibition for singular.
,⩥ Prostaglandins.
Answer: Released when mast cells degranulate, are produced by the
arachidonic pathway. Cause vasodilation, platelet aggregation at site of
injury, pain, and fever.
⩥ Chemotactic factors.
Answer: Biochemical substance that attracts leukocyte to the site of
inflammation
⩥ Neutrophils.
Answer: Predominant leukocyte at work during the early stages of acute
inflammation
⩥ Monocytes.
Answer: Become macrophages when entering the tissue, responsible for
presenting antigens to the CD4 cell which triggers T-cell immunity and
B-cell immunity.
Releases additional cytokines IL1, IL6, TNF.
⩥ Cytokine IL1 function.
Answer: Causes fever, activates phagocytes & lymphocytes and also
increases the release of IL6a
⩥ Cytokine IL6 function.
, Answer: Stimulates production of acute phase reactants and promotes
growth and stimulation of RBCs
⩥ Cytokine TNF function.
Answer: Causes fever, increases synthesis of proinflammatory proteins
by liver, causes muscle wasting, induces thrombosis
⩥ Cytokine growth factor function.
Answer: Promotes production and maturation of neutrophils
⩥ Complement.
Answer: Functions include bacterial lysis, vasodilation and increased
vascular permeability, triggers mast cell degranulation, chemotaxis, and
opsonization.
⩥ Kinin.
Answer: Converted to bradykinin which is responsible for pain and
chemotaxis, and it increases vascular permeability and vasodilation.
⩥ Coagulation cascade.
Answer: Factor XII activates kinin. Function is to form fibrin mesh to
stop bleeding and trap micro organisms.
⩥ COX1.
QUESTIONS AND ANSWERS FULL
SOLUTION GRADED A+
⩥ Mast cell.
Answer: Cellular bags of granules located in loose connective tisssue
close to blood vessels. Activation initiates inflammatory process.
⩥ Histamine.
Answer: Causes vasodilation, increases vascular permeability, increases
blood flow to the site of injury- causes erythema and swelling.
⩥ Cytokines.
Answer: Soluble factors that contribute to the regulation of innate or
adaptive resistance by affecting other neighboring cells. Can be pro-
inflammatory or anti-inflammatory. Can react quickly or be more
delayed.
⩥ Leukotrines.
Answer: Released when mast cells degranulate, prolong the
inflammatory process. Cause vasodilation, attract neutrophils,
monocytes, and eosinophils.target of inhibition for singular.
,⩥ Prostaglandins.
Answer: Released when mast cells degranulate, are produced by the
arachidonic pathway. Cause vasodilation, platelet aggregation at site of
injury, pain, and fever.
⩥ Chemotactic factors.
Answer: Biochemical substance that attracts leukocyte to the site of
inflammation
⩥ Neutrophils.
Answer: Predominant leukocyte at work during the early stages of acute
inflammation
⩥ Monocytes.
Answer: Become macrophages when entering the tissue, responsible for
presenting antigens to the CD4 cell which triggers T-cell immunity and
B-cell immunity.
Releases additional cytokines IL1, IL6, TNF.
⩥ Cytokine IL1 function.
Answer: Causes fever, activates phagocytes & lymphocytes and also
increases the release of IL6a
⩥ Cytokine IL6 function.
, Answer: Stimulates production of acute phase reactants and promotes
growth and stimulation of RBCs
⩥ Cytokine TNF function.
Answer: Causes fever, increases synthesis of proinflammatory proteins
by liver, causes muscle wasting, induces thrombosis
⩥ Cytokine growth factor function.
Answer: Promotes production and maturation of neutrophils
⩥ Complement.
Answer: Functions include bacterial lysis, vasodilation and increased
vascular permeability, triggers mast cell degranulation, chemotaxis, and
opsonization.
⩥ Kinin.
Answer: Converted to bradykinin which is responsible for pain and
chemotaxis, and it increases vascular permeability and vasodilation.
⩥ Coagulation cascade.
Answer: Factor XII activates kinin. Function is to form fibrin mesh to
stop bleeding and trap micro organisms.
⩥ COX1.
