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HOSA PHARMACY SCIENCE STUDYGUIDE FOR TEST EXAM
WITH CORRECT ACTUAL QUESTIONS AND CORRECTLY WELL
DEFINED ANSWERS LATEST ALREADY GRADED A+
the date after which a product must not be dispensed or used
(expiration date); this is determined by the pharmacist based on when
the product is prepared and its storage conditions
......ANSWER......Beyond Use Dating
a measure of how acidic or basic solution is; close to 1 is more acidic,
and close to 14 is more basic. ......ANSWER......pH
how the cells in our body respond to surrounding fluid; three
classifications--hyperotonic, hypotonic, and isotonic
......ANSWER......Tonicity
a solution that has more particles than the surrounding cells, which
causes water to be drawn out of cells, and the cells to shrivel
......ANSWER......Hypertonic Solution
a solution that has fewer particles than the surrounding cells, which
causes water to be drawn into the cells, and the cells to swell and
sometimes burst ......ANSWER......Hypotonic Solution
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a solution tha has the same amount of particles as the surrounding
cells, so no water will move in or out, and the cell will stay the same
......ANSWER......Isotonic
the ability to combine two or more products without creating a change
in the physical, chemical, or therapeutic effectiveness of the drug
......ANSWER......Compatibility
when two or more drugs than are compatible are combined, a physical
change occurs that can be detected, including cloudiness, temperature,
or a color change ......ANSWER......Physical Incompatibilities
when two or more drugs are combined and are not compatible, a
chemical change occurs that may alter pH of a solution or cause the
decomposition of a component ......ANSWER......Chemical
Incompatibilities
when two or more drugs are combined that are not compatible, it
causes a change in the effectiveness of one or more of the drugs when
administered ......ANSWER......Therapeutic Incompatibilities
-defined by the USP chapter <797>
-assigned according to the probability of contaminating a CSP
......ANSWER......Risk Levels
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involves the mixing of no more than three sterile products within an ISO
class 5 workbench
-example: single transfer of a dosage from a vial into an IV bag
......ANSWER......Low-risk CSPs
involves more complex sterile compounding procedures than low risk,
such as mixing more than three sterile products or administering to
multiple patients
-Example: preparation of total parenteral nutrition (TPN)
......ANSWER......Medium-risk CSPs
involves mixing more than three products and/or one of the products is
not sterile or being compounded in an environment less than ISO class
5; these products must be sterilized before being injected into the
patient
-Example: using a non sterile ingredient in preparing a medication for a
patient ......ANSWER......High-Risk CSPs
intended to be used only for emergency situations or when a patient
requires the immediate use of a CSP; must be administered within one
hour of preparation
-Example: emergency medications for cardiopulmonary resuscitation
......ANSWER......Immediate Use CSP
area where pharmacy personnel prepare for sterile compounding.
including:
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-garbing
-hand washing
-gathering supplies ......ANSWER......Anteroom
place where hoods are housed to be used during sterile compounding;
personnel should not enter unless properly garbed
......ANSWER......Clean Room
system for describing the maximum number of particles in the air
allowed in a room where sterile products are compounded
......ANSWER......International Organization for Standardization (ISO)
used to minimize airborne contamination by filtering 99.97% of
particles sized 0.3 microns and greater ......ANSWER......High-Efficiency
Particulate Airflow Filter (HEPA)
a hood used to prepare CSPs that are not hazardous
-air is pulled into the hood through a prefilter and then filtered through
the HEPA filter before blowing horizontally across the work surface
toward the worker
-technicians must work 6 inches inside the hood to avoid mixing
unfiltered air of the clean room with the HEPA filtered air of the LAFW
......ANSWER......Horizontal Laminar Airflow Workbench (LAFW)
HOSA PHARMACY SCIENCE STUDYGUIDE FOR TEST EXAM
WITH CORRECT ACTUAL QUESTIONS AND CORRECTLY WELL
DEFINED ANSWERS LATEST ALREADY GRADED A+
the date after which a product must not be dispensed or used
(expiration date); this is determined by the pharmacist based on when
the product is prepared and its storage conditions
......ANSWER......Beyond Use Dating
a measure of how acidic or basic solution is; close to 1 is more acidic,
and close to 14 is more basic. ......ANSWER......pH
how the cells in our body respond to surrounding fluid; three
classifications--hyperotonic, hypotonic, and isotonic
......ANSWER......Tonicity
a solution that has more particles than the surrounding cells, which
causes water to be drawn out of cells, and the cells to shrivel
......ANSWER......Hypertonic Solution
a solution that has fewer particles than the surrounding cells, which
causes water to be drawn into the cells, and the cells to swell and
sometimes burst ......ANSWER......Hypotonic Solution
,2|Page
a solution tha has the same amount of particles as the surrounding
cells, so no water will move in or out, and the cell will stay the same
......ANSWER......Isotonic
the ability to combine two or more products without creating a change
in the physical, chemical, or therapeutic effectiveness of the drug
......ANSWER......Compatibility
when two or more drugs than are compatible are combined, a physical
change occurs that can be detected, including cloudiness, temperature,
or a color change ......ANSWER......Physical Incompatibilities
when two or more drugs are combined and are not compatible, a
chemical change occurs that may alter pH of a solution or cause the
decomposition of a component ......ANSWER......Chemical
Incompatibilities
when two or more drugs are combined that are not compatible, it
causes a change in the effectiveness of one or more of the drugs when
administered ......ANSWER......Therapeutic Incompatibilities
-defined by the USP chapter <797>
-assigned according to the probability of contaminating a CSP
......ANSWER......Risk Levels
,3|Page
involves the mixing of no more than three sterile products within an ISO
class 5 workbench
-example: single transfer of a dosage from a vial into an IV bag
......ANSWER......Low-risk CSPs
involves more complex sterile compounding procedures than low risk,
such as mixing more than three sterile products or administering to
multiple patients
-Example: preparation of total parenteral nutrition (TPN)
......ANSWER......Medium-risk CSPs
involves mixing more than three products and/or one of the products is
not sterile or being compounded in an environment less than ISO class
5; these products must be sterilized before being injected into the
patient
-Example: using a non sterile ingredient in preparing a medication for a
patient ......ANSWER......High-Risk CSPs
intended to be used only for emergency situations or when a patient
requires the immediate use of a CSP; must be administered within one
hour of preparation
-Example: emergency medications for cardiopulmonary resuscitation
......ANSWER......Immediate Use CSP
area where pharmacy personnel prepare for sterile compounding.
including:
, 4|Page
-garbing
-hand washing
-gathering supplies ......ANSWER......Anteroom
place where hoods are housed to be used during sterile compounding;
personnel should not enter unless properly garbed
......ANSWER......Clean Room
system for describing the maximum number of particles in the air
allowed in a room where sterile products are compounded
......ANSWER......International Organization for Standardization (ISO)
used to minimize airborne contamination by filtering 99.97% of
particles sized 0.3 microns and greater ......ANSWER......High-Efficiency
Particulate Airflow Filter (HEPA)
a hood used to prepare CSPs that are not hazardous
-air is pulled into the hood through a prefilter and then filtered through
the HEPA filter before blowing horizontally across the work surface
toward the worker
-technicians must work 6 inches inside the hood to avoid mixing
unfiltered air of the clean room with the HEPA filtered air of the LAFW
......ANSWER......Horizontal Laminar Airflow Workbench (LAFW)
