NURS 5357 Neurobiology Exam 3
comprehensive questions _
FREQUENTLY MOST TESTED QUESTIONS
AND VERIFIED SOLUTIONS @ 2026
All of the following are true about the monoamine hypothesis except? - ANSWER-
It explains the delay in response seen with depression treatments
Postmortem studies in depressed patients have found all of the following except?
- ANSWER-Reduced neurons in the hypothalamus
Antidepressants may decrease depressive symptoms and improve neuronal
survival through which of the following effects? - ANSWER-Decrease
glucocorticoids and increase BDNF.
Goals for effective treatment of depression include all of the following except? -
ANSWER-Awaken the prefrontal cortex
Which of the following interventions has not been shown to increase BDNF in
animal models? - ANSWER-Cognitive behavioral therapy
Possible culprits in the etiology of depression include all of the following except? -
ANSWER-Insufficient limbic activity
, One plausible explanation for antidepressant effectiveness is: - ANSWER-Restoring
access to the DNA
The pathological mechanism of bipolar disorder is best described as: - ANSWER-
None of the other ANSWERs
Which brain region may be associated with the cognitive impairment symptoms of
depression? - ANSWER-Dorsolateral Prefrontal Cortex
Which of the following statements is true regarding neuroimaging findings of
brain activation in depression? - ANSWER-Depressed patients have lower activity
in the dorsolateral prefrontal cortex compared to non-depressed individuals.
Depressed patients have higher activity in the amygdala and ventromedial
prefrontal cortex compared to non-depressed individuals.
Depressed patients have inadequate recruitment of the hippocampus compared
to non-depressed individuals.
James comes to you presenting with depressed mood, anhedonia, and loss of
energy. These symptoms can be conceptualized as reflecting reduced positive
affect; such a categorization is theoretically useful because it may direct treatment
choice. Specifically, symptoms of reduced positive affect are hypothetically more
likely to respond to agents that enhance: - ANSWER-Dopamine and possibly
norepinephrine function
Michael is a 42-year-old with bipolar I disorder who frequently exhibits impulsive
symptoms of mania including risk taking and pressured speech during his manic
comprehensive questions _
FREQUENTLY MOST TESTED QUESTIONS
AND VERIFIED SOLUTIONS @ 2026
All of the following are true about the monoamine hypothesis except? - ANSWER-
It explains the delay in response seen with depression treatments
Postmortem studies in depressed patients have found all of the following except?
- ANSWER-Reduced neurons in the hypothalamus
Antidepressants may decrease depressive symptoms and improve neuronal
survival through which of the following effects? - ANSWER-Decrease
glucocorticoids and increase BDNF.
Goals for effective treatment of depression include all of the following except? -
ANSWER-Awaken the prefrontal cortex
Which of the following interventions has not been shown to increase BDNF in
animal models? - ANSWER-Cognitive behavioral therapy
Possible culprits in the etiology of depression include all of the following except? -
ANSWER-Insufficient limbic activity
, One plausible explanation for antidepressant effectiveness is: - ANSWER-Restoring
access to the DNA
The pathological mechanism of bipolar disorder is best described as: - ANSWER-
None of the other ANSWERs
Which brain region may be associated with the cognitive impairment symptoms of
depression? - ANSWER-Dorsolateral Prefrontal Cortex
Which of the following statements is true regarding neuroimaging findings of
brain activation in depression? - ANSWER-Depressed patients have lower activity
in the dorsolateral prefrontal cortex compared to non-depressed individuals.
Depressed patients have higher activity in the amygdala and ventromedial
prefrontal cortex compared to non-depressed individuals.
Depressed patients have inadequate recruitment of the hippocampus compared
to non-depressed individuals.
James comes to you presenting with depressed mood, anhedonia, and loss of
energy. These symptoms can be conceptualized as reflecting reduced positive
affect; such a categorization is theoretically useful because it may direct treatment
choice. Specifically, symptoms of reduced positive affect are hypothetically more
likely to respond to agents that enhance: - ANSWER-Dopamine and possibly
norepinephrine function
Michael is a 42-year-old with bipolar I disorder who frequently exhibits impulsive
symptoms of mania including risk taking and pressured speech during his manic
