Pathopharmacology Test 3 –
Drugs Q&A Study Guide
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Page 1 of 33 Pathopharmacology Test 3 – Drugs Q&A Study Guide.pdf
,PATHOPHARM_ Test 3 Drugs Q&A 2 2026-03-07
Beta Lactam Antibiotics
Penicillins
Cephalosporins
Carbapenems
Monobactams
prototype for penicillins
ampicillin
What's the action of penicillin?
binds to cell wall and causes cell death
What are the most serious adverse effects of penicillin?
rash and anaphylaxis
What is given for:
-treatment or prophylaxis of infectious endocarditis
-Skin and soft tissue, respiratory, GI, & GU infections
penicillin
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,PATHOPHARM_ Test 3 Drugs Q&A 3 2026-03-07
What are contraindications for penicillin?
Hypersensitivity
Renal impairment
What's the BBW for penicillin?
-Can only give IM (penicillin G)
-IV may cause cardiopulmonary arrest
What must you monitor for with penicillin?
BUN and creatinine
What's the prototype for cephalosporins?
cefazolin
What's the action of cephalosporins?
binds to cell wall and causes cell death (bactericidal)
What 2 drugs have known cross-sensitivity with penicillins?
cephalosporins and carbapenems
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, PATHOPHARM_ Test 3 Drugs Q&A 4 2026-03-07
What drug is least likely to have cross-sensitivity with penicillin?
monobactams
What is given for surgical prophylaxis and treatment of infections of the
respiratory tract, skin and soft tissues, bones and joints, urinary tract, brain
and spinal cord, and bloodstream (septicemia) ?
cephalosporins
T/F: Cephalosporins must be taken on an empty stomach
False: take with food or milk
Is there a BBW for cephalosporins?
no
T/F: Antacids decrease absorption of cephalosporins
true
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