1
Nurs 5315: Adv Patho Exam 2 Set 1 Questions
with Correct Answers | Updated (100%
Correct Answers)
First 5 steps in the inflammatory process— Answer: 1. mast cell
degranulation
2. activation of coagulation cascade
3. activation of kinin cascade
4. release of chemotactic factors
5.Activation of the complement cascade
Role/function in the inflammatory process: Complement— Answer:
Form the membrane attack complex
bacterial lysis
vasodilation
Increased vascular permeability
triggers mast cell degranulation
chemotaxis
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,2
opsonization - opsonins tag foreign pathogens for elimination by
phagocytes
Role/function in the inflammatory process: kinin— Answer: turned
into bradykinin which is responsible for pain, chemotaxis and
Increased vascular permeability and vasodilation
Role/function in the inflammatory process: Coagulation cascade—
Answer: plays role in activating the kinin system
Factor XII (Hagemon factor) activates kinin and forms a fibrin mesh
to stop bleeding and trap microorganisms
Role/function in the inflammatory process: chemotactic factors—
Answer: once released attract neutrophils, eosinophils and
monocytes for phagocytosis
Role/function in the inflammatory process: Neutrophils— Answer:
show up at the site of injury in 6-8 hours
Neutrophils express and release cytokines, which in turn amplify
inflammatory reactions by several other cell types. In addition to
recruiting and activating other cells of the immune system,
neutrophils play a key role in the front-line defense against invading
pathogens.
Role/function in the inflammatory process: monocytes— Answer:
Show up in 1-7 days
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, 3
become macrophages
present antigens to the CD4 cell which leads to Tcell immunity
which leads to B cell immunity
Releases IL1, IL6, TNF and growth factors
Role/function in the inflammatory process: Mast cell
degranulation— Answer: triggers the activation of the acute phase
reactants
This leads to the release of histamine, cytokines, leukotrienes,
platelet activation factor and prostaglandins
Role/function in the inflammatory process: Histamine 1 (H1)—
Answer: promotes inflammation
smooth muscles, i.e. bronchi - asthma causes bronchoconstriction
Role/function in the inflammatory process: Histamine 2 (H2)—
Answer: anti-inflammatory properties
gastric mucosa
Role/function in the inflammatory process: cytokines— Answer: IL4
early in the inflammation
IL 13 later in inflammation
TNF
© 2025 All rights reserved
Nurs 5315: Adv Patho Exam 2 Set 1 Questions
with Correct Answers | Updated (100%
Correct Answers)
First 5 steps in the inflammatory process— Answer: 1. mast cell
degranulation
2. activation of coagulation cascade
3. activation of kinin cascade
4. release of chemotactic factors
5.Activation of the complement cascade
Role/function in the inflammatory process: Complement— Answer:
Form the membrane attack complex
bacterial lysis
vasodilation
Increased vascular permeability
triggers mast cell degranulation
chemotaxis
© 2025 All rights reserved
,2
opsonization - opsonins tag foreign pathogens for elimination by
phagocytes
Role/function in the inflammatory process: kinin— Answer: turned
into bradykinin which is responsible for pain, chemotaxis and
Increased vascular permeability and vasodilation
Role/function in the inflammatory process: Coagulation cascade—
Answer: plays role in activating the kinin system
Factor XII (Hagemon factor) activates kinin and forms a fibrin mesh
to stop bleeding and trap microorganisms
Role/function in the inflammatory process: chemotactic factors—
Answer: once released attract neutrophils, eosinophils and
monocytes for phagocytosis
Role/function in the inflammatory process: Neutrophils— Answer:
show up at the site of injury in 6-8 hours
Neutrophils express and release cytokines, which in turn amplify
inflammatory reactions by several other cell types. In addition to
recruiting and activating other cells of the immune system,
neutrophils play a key role in the front-line defense against invading
pathogens.
Role/function in the inflammatory process: monocytes— Answer:
Show up in 1-7 days
© 2025 All rights reserved
, 3
become macrophages
present antigens to the CD4 cell which leads to Tcell immunity
which leads to B cell immunity
Releases IL1, IL6, TNF and growth factors
Role/function in the inflammatory process: Mast cell
degranulation— Answer: triggers the activation of the acute phase
reactants
This leads to the release of histamine, cytokines, leukotrienes,
platelet activation factor and prostaglandins
Role/function in the inflammatory process: Histamine 1 (H1)—
Answer: promotes inflammation
smooth muscles, i.e. bronchi - asthma causes bronchoconstriction
Role/function in the inflammatory process: Histamine 2 (H2)—
Answer: anti-inflammatory properties
gastric mucosa
Role/function in the inflammatory process: cytokines— Answer: IL4
early in the inflammation
IL 13 later in inflammation
TNF
© 2025 All rights reserved
