This document features over 100 multiple-choice questions with verified correct answers from NCOI Exam 4, focusing on the complex interplay between immunity, malignancy, and infection, updated for Fall 2026. It is ideal for nursing students preparing for fundamentals, med-surg, or pharmacology exams with a strong immunologic and oncologic emphasis.
Key topics include:
Immune responses (monocytes, IgG, hypersensitivity types, autoimmunity)
Anaphylaxis management, immunotherapy, and latex allergy
Organ transplant rejection (acute, chronic, GVHD) and immunosuppressive therapy
Cancer development, prevention, and treatment (chemotherapy, radiation, side effects, bone marrow transplant)
Hematologic complications (anemia, thrombocytopenia, neutropenia)
HIV/AIDS pathophysiology, ART side effects, transmission prevention, CD4 count criteria
Opportunistic infections, metabolic changes, and patient adherence strategies
Scenarios test critical thinking and clinical knowledge related to plasmapheresis, tumor-associated antigens, chemotherapy complications, radiation precautions, ART management, and health care–associated infection (HAI) prevention.
This guide is essential for students in ADN, BSN, LPN/LVN, and bridge programs, and supports prep for NCLEX, ATI, and HESI evaluations. It’s also valuable for clinical skill reinforcement in topics like oncology, HIV care, and immunologic nursing.
Keywords:
hypersensitivity
plasmapheresis
anaphylaxis
latex allergy
organ rejection
autoimmune disorders
HIV AIDS
opportunistic infections
chemotherapy care
tumor surveillance
radiation precautions
cancer nutrition
ART complications
immunotherapy
CD4 count
graft-versus-host disease
Voorbeeld van de inhoud
Exam 4 NCOI Immunity and Malignancy
(Ch. 13, 14, 15) Questions and Answers
The function of monocytes in immunity is related to their ability to - 🧠
ANSWER ✔✔Capture antigens by phagocytosis and present them to
lymphocytes.
The reason newborns are protected for the first 6 months of life from
bacterial infections is because of the maternal transmission of - 🧠 ANSWER
✔✔IgG.
In a type I hypersensitivity reaction the primary immunologic disorder
appears to be - 🧠 ANSWER ✔✔Release of chemical mediators from IgE-
bound mast cells and basophils.
The nurse is alerted to possible anaphylactic shock immediately after a
patient has received intramuscular penicillin by the development of - 🧠
ANSWER ✔✔Edema and itching at the injection site.
, The nurse advises a friend who asks him to administer his allergy shots
that - 🧠 ANSWER ✔✔Immunotherapy should only be administered in a
setting where emergency equipment and drugs are available.
Association between HLA antigens and diseases is most commonly found
in what disease conditions? - 🧠 ANSWER ✔✔Autoimmune disorders
A patient is undergoing plasmapheresis for treatment of systemic lupus
erythematosus. The nurse explains that plasmapheresis is used in her
treatment to - 🧠 ANSWER ✔✔Exchange her plasma that contains
antinuclear antibodies with a substitute fluid.
The most common cause of secondary immunodeficiencies is - 🧠 ANSWER
✔✔Drugs
What accurately describes rejection following transplantation? - 🧠 ANSWER
✔✔Hyperacute reaction can usually be avoided if crossmatching is done
before the transplantation.
In a person having an acute rejection of a transplanted kidney, what would
help the nurse understand the course of events (select all that apply)? - 🧠
ANSWER ✔✔Acute rejection can be treated with OKT3