NSG 5003 Week 3Quiz Knowledge Check Advanced Pathophysiology South University | 100% Verified
And Correct Answers Latest Updates
Hypersensitivity is best defined as a(an) - (ANSWER)c.
Altered immunologic response to an antigen that results in disease
A hypersensitivity reaction that produces an allergic response is called: - (ANSWER)Anaphylaxis
The common hay fever allergy is expressed through a reaction that is mediated by which class of
immunoglobulins? - (ANSWER)IgE
Which type of antibody is involved in type I hypersensitivity reaction? - (ANSWER)IgE
Blood transfusion reactions are an example of: - (ANSWER)Alloimmunity
During an IgE-mediated hypersensitivity reaction, which leukocyte is activated? - (ANSWER)c.
Eosinophils
During an IgE-mediated hypersensitivity reaction, the degranulation of mast cells is a result of which
receptor action? - (ANSWER)Histamine bound to H2
What characteristic do atopic individuals have that make them genetically predisposed to develop
allergies? - (ANSWER)c.
Greater quantities of IgE
What is the mechanism that results in type II hypersensitivity reactions? - (ANSWER)d.
Antibodies bind to the antigens on the cell surface.
When mismatched blood is administered causing an ABO incompatibility, the erythrocytes are
destroyed by - (ANSWER)a.
Complement-mediated cell lysis
,NSG 5003 Week 3Quiz Knowledge Check Advanced Pathophysiology South University | 100% Verified
And Correct Answers Latest Updates
When antibodies are formed against red blood cell antigens of the Rh system, the blood cells are
destroyed by: - (ANSWER)Phagocytosis in the spleen
When soluble antigens from infectious agents enter circulation, tissue damage is a result of: -
(ANSWER)d.
Neutrophil granules and toxic oxygen products
How are target cells destroyed in a type II hypersensitivity reaction? - (ANSWER)d.
Natural killer cells
Graves disease (hyperthyroidism) is an example of which type II hypersensitivity reaction? -
(ANSWER)Modulation
Type III hypersensitivity reactions are a result of which of the following? - (ANSWER)b.
Antibodies binding to soluble antigens that were released into body fluids and the immune complexes
being deposited in the tissues
A type IV hypersensitivity reaction causes which result? - (ANSWER).
Lymphokine-producing Th1 cells directly attacking and destroying cellular targets
In a type III hypersensitivity reaction, the harmful effects after the immune complexes that are
deposited in tissues are a result of: - (ANSWER)Complement activation
Raynaud phenomenon is classified as a type III hypersensitivity reaction and is due to: - (ANSWER)a.
Immune complexes that are deposited in capillary beds, blocking circulation
Deficiencies in which element can produce depression of both B- and T-cell function? - (ANSWER)Zinc
When the maternal immune system becomes sensitized against antigens expressed by the fetus, what
reaction occurs? - (ANSWER)Alloimmunity
, NSG 5003 Week 3Quiz Knowledge Check Advanced Pathophysiology South University | 100% Verified
And Correct Answers Latest Updates
Tissue damage caused by the deposition of circulating immune complexes containing an antibody
against the host DNA is the cause of which disease? - (ANSWER)Systemic lupus erythematosus
Why does tissue damage occurs in acute rejection after organ transplantation? - (ANSWER)a.
Th1 cells release cytokines that activate infiltrating macrophages, and cytotoxic T cells directly attack the
endothelial cells of the transplanted tissue.
Which blood cell carries the carbohydrate antigens for blood type? - (ANSWER)Erythrocytes
A person with type O blood is likely to have high titers of which anti-antibodies? - (ANSWER)A and B
Which class of immunoglobulins forms isohemagglutinins? - (ANSWER)IgM
Which component of the immune system is deficient in individuals with infections caused by viruses,
fungi, or yeast? - (ANSWER)T cells
In which primary immune deficiency is there a partial-to-complete absence of T-cell immunity? -
(ANSWER)DiGeorge syndrome
How many months does it take for the newborn to be sufficiently protected by antibodies produced by
its own B cells? - (ANSWER)6 to 8
Considering the effects of nutritional deficiencies on the immune system, severe deficits in calories and
protein lead to deficiencies in the formation of which immune cells? - (ANSWER)T cells
Urticaria are a manifestation of a which type of hypersensitivity reaction? - (ANSWER)Type I
Graves disease is a result of: - (ANSWER)c.
Autoantibodies binding to thyroid-stimulating hormone (TSH)-receptor sites
And Correct Answers Latest Updates
Hypersensitivity is best defined as a(an) - (ANSWER)c.
Altered immunologic response to an antigen that results in disease
A hypersensitivity reaction that produces an allergic response is called: - (ANSWER)Anaphylaxis
The common hay fever allergy is expressed through a reaction that is mediated by which class of
immunoglobulins? - (ANSWER)IgE
Which type of antibody is involved in type I hypersensitivity reaction? - (ANSWER)IgE
Blood transfusion reactions are an example of: - (ANSWER)Alloimmunity
During an IgE-mediated hypersensitivity reaction, which leukocyte is activated? - (ANSWER)c.
Eosinophils
During an IgE-mediated hypersensitivity reaction, the degranulation of mast cells is a result of which
receptor action? - (ANSWER)Histamine bound to H2
What characteristic do atopic individuals have that make them genetically predisposed to develop
allergies? - (ANSWER)c.
Greater quantities of IgE
What is the mechanism that results in type II hypersensitivity reactions? - (ANSWER)d.
Antibodies bind to the antigens on the cell surface.
When mismatched blood is administered causing an ABO incompatibility, the erythrocytes are
destroyed by - (ANSWER)a.
Complement-mediated cell lysis
,NSG 5003 Week 3Quiz Knowledge Check Advanced Pathophysiology South University | 100% Verified
And Correct Answers Latest Updates
When antibodies are formed against red blood cell antigens of the Rh system, the blood cells are
destroyed by: - (ANSWER)Phagocytosis in the spleen
When soluble antigens from infectious agents enter circulation, tissue damage is a result of: -
(ANSWER)d.
Neutrophil granules and toxic oxygen products
How are target cells destroyed in a type II hypersensitivity reaction? - (ANSWER)d.
Natural killer cells
Graves disease (hyperthyroidism) is an example of which type II hypersensitivity reaction? -
(ANSWER)Modulation
Type III hypersensitivity reactions are a result of which of the following? - (ANSWER)b.
Antibodies binding to soluble antigens that were released into body fluids and the immune complexes
being deposited in the tissues
A type IV hypersensitivity reaction causes which result? - (ANSWER).
Lymphokine-producing Th1 cells directly attacking and destroying cellular targets
In a type III hypersensitivity reaction, the harmful effects after the immune complexes that are
deposited in tissues are a result of: - (ANSWER)Complement activation
Raynaud phenomenon is classified as a type III hypersensitivity reaction and is due to: - (ANSWER)a.
Immune complexes that are deposited in capillary beds, blocking circulation
Deficiencies in which element can produce depression of both B- and T-cell function? - (ANSWER)Zinc
When the maternal immune system becomes sensitized against antigens expressed by the fetus, what
reaction occurs? - (ANSWER)Alloimmunity
, NSG 5003 Week 3Quiz Knowledge Check Advanced Pathophysiology South University | 100% Verified
And Correct Answers Latest Updates
Tissue damage caused by the deposition of circulating immune complexes containing an antibody
against the host DNA is the cause of which disease? - (ANSWER)Systemic lupus erythematosus
Why does tissue damage occurs in acute rejection after organ transplantation? - (ANSWER)a.
Th1 cells release cytokines that activate infiltrating macrophages, and cytotoxic T cells directly attack the
endothelial cells of the transplanted tissue.
Which blood cell carries the carbohydrate antigens for blood type? - (ANSWER)Erythrocytes
A person with type O blood is likely to have high titers of which anti-antibodies? - (ANSWER)A and B
Which class of immunoglobulins forms isohemagglutinins? - (ANSWER)IgM
Which component of the immune system is deficient in individuals with infections caused by viruses,
fungi, or yeast? - (ANSWER)T cells
In which primary immune deficiency is there a partial-to-complete absence of T-cell immunity? -
(ANSWER)DiGeorge syndrome
How many months does it take for the newborn to be sufficiently protected by antibodies produced by
its own B cells? - (ANSWER)6 to 8
Considering the effects of nutritional deficiencies on the immune system, severe deficits in calories and
protein lead to deficiencies in the formation of which immune cells? - (ANSWER)T cells
Urticaria are a manifestation of a which type of hypersensitivity reaction? - (ANSWER)Type I
Graves disease is a result of: - (ANSWER)c.
Autoantibodies binding to thyroid-stimulating hormone (TSH)-receptor sites
