C HAPTER 41: A NTITUBERCULAR D RUGS
Lilley: Pharmacology and the Nursing Process, 10th Edition
MULTIPLE CHOICE
1. The nurse is counseling a woman who will be starting rifampin as part of
antitubercular therapy. The patient is currentl y taking oral contraceptives.
Which statement is true regarding rifampin therapy for this patient?
a. Women have a high risk for thrombophlebitis while on this drug.
b. A higher dose of rifampin will be necessary because of the
contraceptive.
c. Oral contraceptives are less effective while the patient is taking
rifampin.
d. The incidence of adverse effects is greater if the two drugs are
taken together.
ANS: C
Women taking oral contraceptives and rifampin need to be counseled
about other forms of birth contro l because of the impaired
effectiveness of the oral contraceptives during concurrent use of
rifampin.
DIF: Cognitive Level: Understanding (Comprehension)
TOP: Nursing Process: Implementation
MSC: NC LEX: Physiological Integrit y: Physiological Adaptation
2. The nurse is reviewing the medication administration record of a patient
who is taking isoniazid. Which drug or drug class has a significant drug
interaction with isoniazid?
, a. Pyridoxine
b. Penicillins
c. Phenytoin
d. Benzodiazepines
ANS: C
Taking INH with phenytoin w ill cause decreased metabolism of the
phenytoin, leading to increased drug effects. P yridoxine is often given
with isoniazid to prevent peripheral neuropathy. The other options are
incorrect.
DIF: Cognitive Level: Understanding (Comprehension)
TOP: Nursing Process: Implementation
MSC: NC LEX: Physiological Integrit y: Pharmacological and
Parenteral Therapies
3. A patient who has started drug therapy for tuberculosis wants to know
how long he will be on the medications. Which response by the nurse is
correct?
a. “Drug therapy will last until the symptoms have stopped. ”
b. “Drug therapy will continue until the tuberculosis develops
resistance. ”
c. “You should expect to take these drugs for as long as 12 months. ”
d. “You will be on this drug therapy for the rest of your life. ”
ANS: C
Drug therapy can last for up to 12 months if consistent drug therapy
has been maintained. The other options are incorrect.
DIF: Cognitive Level: Anal yzing (Anal ysis)
TOP: Nursing Process: Implementation
Lilley: Pharmacology and the Nursing Process, 10th Edition
MULTIPLE CHOICE
1. The nurse is counseling a woman who will be starting rifampin as part of
antitubercular therapy. The patient is currentl y taking oral contraceptives.
Which statement is true regarding rifampin therapy for this patient?
a. Women have a high risk for thrombophlebitis while on this drug.
b. A higher dose of rifampin will be necessary because of the
contraceptive.
c. Oral contraceptives are less effective while the patient is taking
rifampin.
d. The incidence of adverse effects is greater if the two drugs are
taken together.
ANS: C
Women taking oral contraceptives and rifampin need to be counseled
about other forms of birth contro l because of the impaired
effectiveness of the oral contraceptives during concurrent use of
rifampin.
DIF: Cognitive Level: Understanding (Comprehension)
TOP: Nursing Process: Implementation
MSC: NC LEX: Physiological Integrit y: Physiological Adaptation
2. The nurse is reviewing the medication administration record of a patient
who is taking isoniazid. Which drug or drug class has a significant drug
interaction with isoniazid?
, a. Pyridoxine
b. Penicillins
c. Phenytoin
d. Benzodiazepines
ANS: C
Taking INH with phenytoin w ill cause decreased metabolism of the
phenytoin, leading to increased drug effects. P yridoxine is often given
with isoniazid to prevent peripheral neuropathy. The other options are
incorrect.
DIF: Cognitive Level: Understanding (Comprehension)
TOP: Nursing Process: Implementation
MSC: NC LEX: Physiological Integrit y: Pharmacological and
Parenteral Therapies
3. A patient who has started drug therapy for tuberculosis wants to know
how long he will be on the medications. Which response by the nurse is
correct?
a. “Drug therapy will last until the symptoms have stopped. ”
b. “Drug therapy will continue until the tuberculosis develops
resistance. ”
c. “You should expect to take these drugs for as long as 12 months. ”
d. “You will be on this drug therapy for the rest of your life. ”
ANS: C
Drug therapy can last for up to 12 months if consistent drug therapy
has been maintained. The other options are incorrect.
DIF: Cognitive Level: Anal yzing (Anal ysis)
TOP: Nursing Process: Implementation
