Harr ISBB question n answers 2023 passed

Harr ISBBWhat type of serological testing does the blood bank technologist perform when determining the blood group of a patient? A. Genotyping B. Phenotyping C. Both genotyping and phenotyping D. Polymerase chain reaction B Phenotyping, or the physical expression of a genotype, is the type of testing routinely performed in the blood bank. An individual, for example, may have the AO genotype but phenotypes as group A. If anti-K reacts 3+ with a donor cell with a genotype KK and 2+ with a Kk cell, the antibody is demonstrating: A. Dosage B. Linkage disequilibrium C. Homozygosity D. Heterozygosity A Dosage is defined as an antibody reacting stronger with homozygous cells (such as KK) than with heterozygous cells (such as Kk). In addition to Kell, dosage effect is seen commonly with antigens M, N, S, s, Fya, Fyb, Jka, Jkb, and the antigens of the Rh system. Carla expresses the blood group antigens Fya, Fyb, and Xga. James shows expressions of none of these antigens. What factor(s) may account for the absence of these antigens in James? A. Gender B. Race C. Gender and race D. Medication C The frequency of Duffy antigens Fya and Fyb varies with race. The Fy(a−b−) phenotype occurs in almost 70% of African Americans and is very rare in whites. The Xga antigen is X-linked and, therefore, expressed more frequently in women (who may inherit the antigen from either parent) than in men. Which of the following statements is true? A. An individual with the BO genotype is homozygous for B antigen B. An individual with the BB genotype is homozygous for B antigen C. An individual with the OO genotype is heterozygous for O antigen D. An individual with the AB phenotype is homozygous for A and B antigens B An individual having the BB genotype has inherited the B gene from both parents and, therefore, is homozygous for B antigen. Which genotype is heterozygous for C? A. DCedce B. DCEDCE C. Dcedce D. DCEdCe A The genotype DCedce contains one C and one c gene and is heterozygous for C and c antigens. Which genotype(s) will give rise to the Bombay phenotype? A. HH only B. HH and Hh C. Hh and hh D. hh only D The Bombay phenotype will be expressed only when no H substance is present. The Oh type is expressed by the genotype hh. Bombays produce naturally occurring anti-H, and their serum agglutinates group O red cells in addition to red cells from groups A, B, and AB persons. Meiosis in cell division is limited to the ova and sperm producing four gametes containing what complement of DNA? A. 1N B. 2N C. 3N D. 4N A Meiosis involves two nuclear divisions in succession resulting in four gametocytes each containing half the number of chromosomes found in somatic cells or 1N. A cell that is not actively dividing is said to be in: A. Interphase B. Prophase C. Anaphase D. Telophase A Interphase is the stage in between cell divisions. The cell is engaged in metabolic activity. Chromosomes are not clearly discerned; however, nucleoli may be visible.