HESI RN PHARMACOLOGY EXAM REAL EXAM 2026 | ALL
160 QUESTIONS AND CORRECT ANSWERS | VERIFIED
ANSWERS | JUST RELEASED
A client prescribed clindamycin hydrochloride intravenously asks the
nurse why blood has to be drawn before the third dose and one hour
after the completion of the administration of the medication. Which
information should the nurse provide the client to answer the
question?
A. the onset action for the medication occurs very quickly
B. A small margin exists between safe and toxic plasma levels
C. Bioavailability is significantly reduced by the first-pass effect
D. Standard dosage is needed for the medication to be effective ----------
--Correct Answer--------------------B
A pediatric client diagnosed with partial seizures receives a prescription
for topiramate. Which information should the nurse provide to the
child's parents?
A. do not crush the tablet prior to administration
B. Give the medication with 8 oz of orange juice
C. Avoid prolonged exposure to direct sunlight
,D. Administer the tablet an hour before meals ------------Correct Answer-
-------------------A
A male client with meningitis is prescribed cefotaxime (Claforan) IV and
asks the nurse why he cannot receive an oral drug, such as cefaclor
(Ceclor) or cefadroxil (Duricef), that he has taken before infections.
How should the nurse respond when considering the actions of
cephalosporins?
A. Cefazolin (Ancef) is another IV antibiotic that can be prescribed
B. Cefaclor (Ceclor) is a good alternative to suggest to the healthcare
provider
C. Cefadroxil (Duricef) is usually prescribed when the IV is discontinued
D. Cefotaxime (Claforan) provides therapeutic CNS concentrations -------
-----Correct Answer--------------------D
A client experiencing pain from metastatic cancer is prescribed
morphine. Which route of administration should the nurse clarify with
the healthcare provider prior to administering the medication?
A. Oral
B. Buccal
C. Sublingual
,D. Intravenous ------------Correct Answer--------------------A
Which statement by a client warrants further instruction by the nurse
about the changing insulin needs of a diabetic client during pregnancy?
A. "Eisodes of hypoglycemia are more likely to occur during the first 3
months"
B. "I will increase my insulin dosage by 5 units each month during the
first trimester"
C. "Insulin dosage will likely need to be increased during the second and
third trimesters"
D. "Breastfeeding will decrease my insulin needs to lower than my
prepregnancy levels" ------------Correct Answer--------------------B
A client with chronic gouty arthritis prescribed allopurinol is
experiencing an acute attack of gouty arthritis. The healthcare provider
prescribes concurrent low-dose colchicine. Which information should
the nurse provide the client that best explains the action of the
colchicine?
A. It acts like aspirin to relieve pain
B. It facilitates the excretion of uric acid
C. It reduces the inflammation at the affected site
, D. It prevents the formation of uric acid crystals ------------Correct
Answer--------------------C
The healthcare provider prescribes oral antifungal therapy for a client
with onychomycosis. Which information should the nurse provide the
client?
A. A single dose of the oral antifungal agent is usually sufficient to treat
the infection
B. The infection is difficult to eradicate and requires prolonged therapy
for 3 to 6 months
C. Complete eradication is important because of the risk of a systemic
infection
D. Prolonged therapy provides no benefit and increases the risk of
adverse effcts ------------Correct Answer--------------------B
A client receives a prescription for sulfamethoxazole-trimethoprim
(septra) for a urinary tract infection (UTI). Which instruction should the
nurse provide to the client?
A. Ingest food prior to taking the antibiotic
B. Drink at least 8 glasses for water a day
C. take the medication with grapefruit juice
160 QUESTIONS AND CORRECT ANSWERS | VERIFIED
ANSWERS | JUST RELEASED
A client prescribed clindamycin hydrochloride intravenously asks the
nurse why blood has to be drawn before the third dose and one hour
after the completion of the administration of the medication. Which
information should the nurse provide the client to answer the
question?
A. the onset action for the medication occurs very quickly
B. A small margin exists between safe and toxic plasma levels
C. Bioavailability is significantly reduced by the first-pass effect
D. Standard dosage is needed for the medication to be effective ----------
--Correct Answer--------------------B
A pediatric client diagnosed with partial seizures receives a prescription
for topiramate. Which information should the nurse provide to the
child's parents?
A. do not crush the tablet prior to administration
B. Give the medication with 8 oz of orange juice
C. Avoid prolonged exposure to direct sunlight
,D. Administer the tablet an hour before meals ------------Correct Answer-
-------------------A
A male client with meningitis is prescribed cefotaxime (Claforan) IV and
asks the nurse why he cannot receive an oral drug, such as cefaclor
(Ceclor) or cefadroxil (Duricef), that he has taken before infections.
How should the nurse respond when considering the actions of
cephalosporins?
A. Cefazolin (Ancef) is another IV antibiotic that can be prescribed
B. Cefaclor (Ceclor) is a good alternative to suggest to the healthcare
provider
C. Cefadroxil (Duricef) is usually prescribed when the IV is discontinued
D. Cefotaxime (Claforan) provides therapeutic CNS concentrations -------
-----Correct Answer--------------------D
A client experiencing pain from metastatic cancer is prescribed
morphine. Which route of administration should the nurse clarify with
the healthcare provider prior to administering the medication?
A. Oral
B. Buccal
C. Sublingual
,D. Intravenous ------------Correct Answer--------------------A
Which statement by a client warrants further instruction by the nurse
about the changing insulin needs of a diabetic client during pregnancy?
A. "Eisodes of hypoglycemia are more likely to occur during the first 3
months"
B. "I will increase my insulin dosage by 5 units each month during the
first trimester"
C. "Insulin dosage will likely need to be increased during the second and
third trimesters"
D. "Breastfeeding will decrease my insulin needs to lower than my
prepregnancy levels" ------------Correct Answer--------------------B
A client with chronic gouty arthritis prescribed allopurinol is
experiencing an acute attack of gouty arthritis. The healthcare provider
prescribes concurrent low-dose colchicine. Which information should
the nurse provide the client that best explains the action of the
colchicine?
A. It acts like aspirin to relieve pain
B. It facilitates the excretion of uric acid
C. It reduces the inflammation at the affected site
, D. It prevents the formation of uric acid crystals ------------Correct
Answer--------------------C
The healthcare provider prescribes oral antifungal therapy for a client
with onychomycosis. Which information should the nurse provide the
client?
A. A single dose of the oral antifungal agent is usually sufficient to treat
the infection
B. The infection is difficult to eradicate and requires prolonged therapy
for 3 to 6 months
C. Complete eradication is important because of the risk of a systemic
infection
D. Prolonged therapy provides no benefit and increases the risk of
adverse effcts ------------Correct Answer--------------------B
A client receives a prescription for sulfamethoxazole-trimethoprim
(septra) for a urinary tract infection (UTI). Which instruction should the
nurse provide to the client?
A. Ingest food prior to taking the antibiotic
B. Drink at least 8 glasses for water a day
C. take the medication with grapefruit juice
