🩺 HESI RN Pharmacology Q-Bank – 2027–2028 Edition
Verified Questions with Detailed Rationales
HealthStudyPro | Trusted Nursing Exam Support
Document Type:
Question Bank for HESI RN Students
Updated:
2025–2026 Academic Year
Includes:
• 100+ Pharmacology Practice Questions
• NCLEX/HESI-Style Format
• Multiple Choice, SATA & Clinical Judgment
• Verified Correct Answers
• Detailed Answer Rationales
Best Used For:
HESI RN Pharmacology Prep | NCLEX Review | Nursing Exam Success
Created by:
HealthStudyPro
Helping Nursing Students Pass with Confidence
Email:
WhatsApp: +254727526142
,Welcome to the HESI RN Pharmacology Q-Bank (2025–2026 Edition), created by
HealthStudyPro to support nursing students preparing for the HESI exit exam and NCLEX-RN
with focused, high-yield pharmacology practice.
This question bank includes 100+ carefully selected questions, designed in the HESI exam
style, covering critical pharmacology concepts tested in real clinical settings. Each question is
followed by a correct answer and a brief but thorough rationale to help you not just
memorize, but understand the “why” behind each answer.
,Question 1
A nurse is administering furosemide (Lasix) to a client with heart failure. Which electrolyte
imbalance should the nurse monitor most closely?
A. Hyperkalemia
B. Hypokalemia
C. Hypernatremia
D. Hypocalcemia
Correct Answer: B. Hypokalemia
Rationale:
Furosemide is a loop diuretic that causes potassium excretion. The nurse should monitor for
hypokalemia, which can cause muscle cramps, weakness, or cardiac dysrhythmias.
Question 2
A client is prescribed warfarin (Coumadin). Which of the following instructions is most
important for the nurse to include?
A. Avoid green leafy vegetables entirely
B. Report signs of bleeding
C. Take with antacids to prevent stomach upset
D. Expect your urine to turn orange
Correct Answer: B. Report signs of bleeding
Rationale:
Warfarin is an anticoagulant. Patients should be instructed to watch for signs of bleeding
(bruising, gum bleeding, black stools). Vitamin K intake should be consistent, not eliminated.
Question 3
A nurse is reviewing a new order for digoxin (Lanoxin). What is the priority nursing
assessment before administering the drug?
A. Blood pressure
B. Respiratory rate
C. Apical pulse
D. Bowel sounds
, Correct Answer: C. Apical pulse
Rationale:
Digoxin can cause bradycardia. The apical pulse should be checked for 1 full minute, and the
drug should be held if the heart rate is <60 bpm.
Question 4
Which adverse effect should the nurse monitor for in a patient receiving gentamicin?
A. Constipation
B. Tinnitus
C. Rash
D. Hypertension
Correct Answer: B. Tinnitus
Rationale:
Gentamicin is an aminoglycoside antibiotic that is ototoxic. Tinnitus, hearing loss, or balance
issues should be reported immediately.
Question 5
A patient taking lisinopril reports a persistent dry cough. What should the nurse anticipate?
A. The medication dose will be increased
B. The patient should increase fluid intake
C. The medication may be discontinued
D. This is an expected side effect, and no action is needed
Correct Answer: C. The medication may be discontinued
Rationale:
ACE inhibitors like lisinopril commonly cause a dry cough. It’s often persistent and
uncomfortable, leading providers to switch the patient to an ARB (like losartan).
Question 6
Which lab value should be monitored when a patient is on heparin therapy?
Verified Questions with Detailed Rationales
HealthStudyPro | Trusted Nursing Exam Support
Document Type:
Question Bank for HESI RN Students
Updated:
2025–2026 Academic Year
Includes:
• 100+ Pharmacology Practice Questions
• NCLEX/HESI-Style Format
• Multiple Choice, SATA & Clinical Judgment
• Verified Correct Answers
• Detailed Answer Rationales
Best Used For:
HESI RN Pharmacology Prep | NCLEX Review | Nursing Exam Success
Created by:
HealthStudyPro
Helping Nursing Students Pass with Confidence
Email:
WhatsApp: +254727526142
,Welcome to the HESI RN Pharmacology Q-Bank (2025–2026 Edition), created by
HealthStudyPro to support nursing students preparing for the HESI exit exam and NCLEX-RN
with focused, high-yield pharmacology practice.
This question bank includes 100+ carefully selected questions, designed in the HESI exam
style, covering critical pharmacology concepts tested in real clinical settings. Each question is
followed by a correct answer and a brief but thorough rationale to help you not just
memorize, but understand the “why” behind each answer.
,Question 1
A nurse is administering furosemide (Lasix) to a client with heart failure. Which electrolyte
imbalance should the nurse monitor most closely?
A. Hyperkalemia
B. Hypokalemia
C. Hypernatremia
D. Hypocalcemia
Correct Answer: B. Hypokalemia
Rationale:
Furosemide is a loop diuretic that causes potassium excretion. The nurse should monitor for
hypokalemia, which can cause muscle cramps, weakness, or cardiac dysrhythmias.
Question 2
A client is prescribed warfarin (Coumadin). Which of the following instructions is most
important for the nurse to include?
A. Avoid green leafy vegetables entirely
B. Report signs of bleeding
C. Take with antacids to prevent stomach upset
D. Expect your urine to turn orange
Correct Answer: B. Report signs of bleeding
Rationale:
Warfarin is an anticoagulant. Patients should be instructed to watch for signs of bleeding
(bruising, gum bleeding, black stools). Vitamin K intake should be consistent, not eliminated.
Question 3
A nurse is reviewing a new order for digoxin (Lanoxin). What is the priority nursing
assessment before administering the drug?
A. Blood pressure
B. Respiratory rate
C. Apical pulse
D. Bowel sounds
, Correct Answer: C. Apical pulse
Rationale:
Digoxin can cause bradycardia. The apical pulse should be checked for 1 full minute, and the
drug should be held if the heart rate is <60 bpm.
Question 4
Which adverse effect should the nurse monitor for in a patient receiving gentamicin?
A. Constipation
B. Tinnitus
C. Rash
D. Hypertension
Correct Answer: B. Tinnitus
Rationale:
Gentamicin is an aminoglycoside antibiotic that is ototoxic. Tinnitus, hearing loss, or balance
issues should be reported immediately.
Question 5
A patient taking lisinopril reports a persistent dry cough. What should the nurse anticipate?
A. The medication dose will be increased
B. The patient should increase fluid intake
C. The medication may be discontinued
D. This is an expected side effect, and no action is needed
Correct Answer: C. The medication may be discontinued
Rationale:
ACE inhibitors like lisinopril commonly cause a dry cough. It’s often persistent and
uncomfortable, leading providers to switch the patient to an ARB (like losartan).
Question 6
Which lab value should be monitored when a patient is on heparin therapy?
