HUIDZIEKTEN 2025-2026
Histologie van de huid (NIET)....................................................................................................................... 6
Inleidende begrippen................................................................................................................................... 10
Dermatologie............................................................................................................................................ 10
Diagnostiek...............................................................................................................................................12
Oefeningen...............................................................................................................................................15
Psoriasis & psoriasiforme huidziekten...................................................................................................... 16
Psoriasis...................................................................................................................................................16
Pityriasis Rosea van Gibert...................................................................................................................... 21
Acné, rosacea & acneïforme huidziekten.................................................................................................. 22
Acné......................................................................................................................................................... 22
Rosacea................................................................................................................................................... 25
Peri-orale dermatitis = clownseczeem..................................................................................................... 26
Hidradenitis suppurativa...........................................................................................................................26
Hidradenitis suppurativa............................................................................................................................. 28
Hidradenitis suppurativa...........................................................................................................................28
Behandeling............................................................................................................................................. 29
Huidinfecties (bacterieel & viraal).............................................................................................................. 32
Huidinfecties.............................................................................................................................................32
Bacteriële huidinfecties............................................................................................................................ 32
Klassieke bacteriële huidinfecties...................................................................................................... 32
Bijzondere bacteriële huidinfecties.....................................................................................................36
Virale huidinfecties................................................................................................................................... 39
Klassieke virale huidinfecties............................................................................................................. 39
Andere virale huidinfecties................................................................................................................. 43
Huidinfecties (gisten & schimmels)........................................................................................................... 44
Schimmels & gisten..................................................................................................................................44
Schimmelinfecties.................................................................................................................................... 44
Gisten infecties.........................................................................................................................................48
Candida.............................................................................................................................................. 48
Malassezia = Pityrosporon................................................................................................................. 50
Huidinfecties (parasitair)............................................................................................................................. 53
Scabiës = schurft......................................................................................................................................53
Pediculosis = luizen..................................................................................................................................55
Hoofdluizen........................................................................................................................................ 55
Schaamluizen.....................................................................................................................................55
Demodex.................................................................................................................................................. 55
Leishmania (NIET)................................................................................................................................... 56
Larva migrans (NIET)............................................................................................................................... 56
Insectenbeten...........................................................................................................................................56
Huidinfecties (SOA)..................................................................................................................................... 58
Syfilis........................................................................................................................................................ 58
Gonorroe.................................................................................................................................................. 60
Chlamydia................................................................................................................................................ 60
Andere SOA’s...........................................................................................................................................60
HIV (NIET)................................................................................................................................................60
1
,Eczeem & kinderdermatologie....................................................................................................................62
Eczeem.................................................................................................................................................... 62
Atopisch eczeem (AD) = constitutioneel eczeem.....................................................................................62
Andere eczemen...................................................................................................................................... 68
Contact allergisch eczeem................................................................................................................. 68
Contact irritatief eczeem.....................................................................................................................68
Seborroïsch eczeem.......................................................................................................................... 68
Nummulair eczeem............................................................................................................................ 69
Variceus / veneus / stase eczeem...................................................................................................... 69
Asteatotisch / craquelé eczeem......................................................................................................... 69
Dishydrosiform (dyshidrotisch) eczeem............................................................................................. 69
Lichen simplex chronicus = neurodermitis......................................................................................... 69
Prurigo nodularis = knobbeleczeem................................................................................................... 69
Handeczeem...................................................................................................................................... 70
Kinderdermatologie.................................................................................................................................. 70
Bacteriële infecties............................................................................................................................. 70
Virale infecties.................................................................................................................................... 71
Parasitaire infecties............................................................................................................................ 71
Congenitale naevus............................................................................................................................71
Vasculaire naevi................................................................................................................................. 71
Luierdermatitis....................................................................................................................................72
Pityriasis alba..................................................................................................................................... 72
Seborrhoea capitis neonatorum......................................................................................................... 73
Acne................................................................................................................................................... 73
Fotodermatosen & fototherapie..................................................................................................................74
Fotodermatosen - diagnose..................................................................................................................... 75
Fotodermatosen - pathologieën............................................................................................................... 77
Primaire idiopathische fotodermatosen.............................................................................................. 77
Chemische- en medicatie-geïnduceerde fotodermatosen..................................................................78
Pellagra.............................................................................................................................................. 79
Voorbestaande huidaandoeningen.....................................................................................................80
Starten met fototherapie...........................................................................................................................80
Zonbescherming.......................................................................................................................................81
Pigmentatiestoornissen.............................................................................................................................. 86
Hypopigmentatie & depigmentatie........................................................................................................... 86
Vitiligo................................................................................................................................................. 86
Albinisme............................................................................................................................................89
Hyperpigmentatie..................................................................................................................................... 89
Epheliden & lentigines........................................................................................................................89
Melasma = zwangerschapsmasker = chloasma................................................................................ 90
Ziekten / syndromen met hyperpigmentatie....................................................................................... 90
Medicatie-geïnduceerde hyperpigmentatie........................................................................................ 90
Haar- en nagelaandoeningen...................................................................................................................... 92
Haaraandoeningen...................................................................................................................................92
Niet-cicatricieel................................................................................................................................... 93
Cicatricieel..........................................................................................................................................96
Nagelaandoeningen................................................................................................................................. 96
Onychomycose...................................................................................................................................97
Psoriasis...........................................................................................................................................101
2
, Lichen planus................................................................................................................................... 101
Nagels bij oudere patiënten..............................................................................................................101
Distale onycholyse........................................................................................................................... 101
Onychomadese................................................................................................................................ 101
Retronychie...................................................................................................................................... 102
Ingroeiende nagels...........................................................................................................................102
Pyogeen granuloma......................................................................................................................... 102
Nagelmelanoom............................................................................................................................... 102
Cutane oncologie....................................................................................................................................... 104
Photoaging............................................................................................................................................. 104
Benigne huidtumoren............................................................................................................................. 104
Epidermale huidtumoren.................................................................................................................. 104
Dermale tumoren..............................................................................................................................106
Premaligne huidletsels........................................................................................................................... 107
Actinische keratose (AK).................................................................................................................. 107
Kerato-acanthoom............................................................................................................................108
Maligne huidtumoren (uitz. melanoom).................................................................................................. 108
Epidermale tumoren......................................................................................................................... 108
Naevi...................................................................................................................................................... 110
Maligne melanoom (MM)........................................................................................................................ 111
Huidletsels die soms verward worden met naevi / MM.......................................................................... 113
Andere huidtumoren............................................................................................................................... 113
Dermatofibrosarcoma protuberans (DFSP)...................................................................................... 113
Merkcel carcinoom (MCC)................................................................................................................ 114
Atypisch fibroxanthoma (AFX).......................................................................................................... 114
Xeroderma pigmentosum (XP)......................................................................................................... 114
Behandelingen (incl. dermatochirurgie)..................................................................................................116
Huidziekten op de donkere huid............................................................................................................... 118
Reactieve dermatosen, medicamenteuze erupties & zwangerschapsdermatosen............................. 124
Reactieve dermatosen........................................................................................................................... 124
Vasculitis.......................................................................................................................................... 124
Erythema exsudativum multiforme (EEM)........................................................................................126
Erythema nodosum (EN)..................................................................................................................127
Neutrofiele dermatosen.................................................................................................................... 128
Medicamenteuze erupties...................................................................................................................... 131
Milde medicamenteuze erupties.......................................................................................................131
Ernstige medicamenteuze erupties.................................................................................................. 133
Zwangerschapsdermatosen (NIET)....................................................................................................... 136
Vasculitis.....................................................................................................................................................137
Vasculitis................................................................................................................................................ 137
Conclusie................................................................................................................................................141
Pruritus, urticaria & angio-oedeem.......................................................................................................... 142
Pruritus (jeuk)......................................................................................................................................... 142
Urticaria & angio-oedeem.......................................................................................................................147
Blaarziekten................................................................................................................................................ 151
Auto-immune blaarziekten......................................................................................................................151
Bulleus pemfigoïd.............................................................................................................................151
Pemfigus (zie casussen, dia 19-22)................................................................................................. 153
Dermatitis herpetiformis................................................................................................................... 154
3
, Systeemziekten - cutane lupus.................................................................................................................157
Types cutane lupus................................................................................................................................ 157
Systemische lupus erythematosus...................................................................................................157
Discoïde cutane lupus erythematosus............................................................................................. 157
Subacute cutane lupus erythematosus............................................................................................ 157
Acute cutane lupus erythematosus.................................................................................................. 157
Non-specifieke huidafwijkingen bij SLE............................................................................................158
Behandeling cutane LE.......................................................................................................................... 158
Systeemziekten - dermatomyositis.......................................................................................................... 159
Systeemziekten - sclerodermie.................................................................................................................162
Systeemsclerose.................................................................................................................................... 162
Lokale sclerodermie............................................................................................................................... 163
Exogene dermatosen - contacteczeem & psychogene huidziekten..................................................... 164
Contacteczeem...................................................................................................................................... 164
Contact-irritatief eczeem.................................................................................................................. 164
Contact-allergisch eczeem............................................................................................................... 164
Psychogene huidziekten........................................................................................................................ 166
Dermatitis artefacta.......................................................................................................................... 167
Parasietenwaan................................................................................................................................167
Parapsoriasis & huidlymfomen................................................................................................................ 168
Parapsoriasis..........................................................................................................................................168
Huidlymfomen........................................................................................................................................ 168
Mycosis fungoides (Sézary)............................................................................................................. 170
Cutane CD30+ lymfoproliferatieve aandoeningen........................................................................... 171
Cutane B-cellymfomen..................................................................................................................... 172
Paraneoplastische huidaandoeningen.................................................................................................... 174
Paraneoplastische huidaandoeningen................................................................................................... 174
Wondheling & wondzorg........................................................................................................................... 175
Littekens................................................................................................................................................. 175
Lokale behandeling van ulcera.............................................................................................................. 175
Hypergranulerend ulcus......................................................................................................................... 179
Vertraagde wondheling.......................................................................................................................... 179
Atone wonde.......................................................................................................................................... 179
EXAMEN
● 40 MCQ: 4 mogelijke antwoorden, 1 juist antwoord
● geen giscorrectie, geen verhoogde cesuur
● onderdelen
○ belangrijk: huidinfecties, ernstige drugerupties
○ cutane oncologie: melanoom (SCC, BCC), Morbus Bowen, actinische keratose
○ parapsoriasis / cutaan lymfoom + wondzorg → hooguit 1 vraag
foto’s
● www.huidziekten.nl
● www.dermnetnz.org
4
Histologie van de huid (NIET)....................................................................................................................... 6
Inleidende begrippen................................................................................................................................... 10
Dermatologie............................................................................................................................................ 10
Diagnostiek...............................................................................................................................................12
Oefeningen...............................................................................................................................................15
Psoriasis & psoriasiforme huidziekten...................................................................................................... 16
Psoriasis...................................................................................................................................................16
Pityriasis Rosea van Gibert...................................................................................................................... 21
Acné, rosacea & acneïforme huidziekten.................................................................................................. 22
Acné......................................................................................................................................................... 22
Rosacea................................................................................................................................................... 25
Peri-orale dermatitis = clownseczeem..................................................................................................... 26
Hidradenitis suppurativa...........................................................................................................................26
Hidradenitis suppurativa............................................................................................................................. 28
Hidradenitis suppurativa...........................................................................................................................28
Behandeling............................................................................................................................................. 29
Huidinfecties (bacterieel & viraal).............................................................................................................. 32
Huidinfecties.............................................................................................................................................32
Bacteriële huidinfecties............................................................................................................................ 32
Klassieke bacteriële huidinfecties...................................................................................................... 32
Bijzondere bacteriële huidinfecties.....................................................................................................36
Virale huidinfecties................................................................................................................................... 39
Klassieke virale huidinfecties............................................................................................................. 39
Andere virale huidinfecties................................................................................................................. 43
Huidinfecties (gisten & schimmels)........................................................................................................... 44
Schimmels & gisten..................................................................................................................................44
Schimmelinfecties.................................................................................................................................... 44
Gisten infecties.........................................................................................................................................48
Candida.............................................................................................................................................. 48
Malassezia = Pityrosporon................................................................................................................. 50
Huidinfecties (parasitair)............................................................................................................................. 53
Scabiës = schurft......................................................................................................................................53
Pediculosis = luizen..................................................................................................................................55
Hoofdluizen........................................................................................................................................ 55
Schaamluizen.....................................................................................................................................55
Demodex.................................................................................................................................................. 55
Leishmania (NIET)................................................................................................................................... 56
Larva migrans (NIET)............................................................................................................................... 56
Insectenbeten...........................................................................................................................................56
Huidinfecties (SOA)..................................................................................................................................... 58
Syfilis........................................................................................................................................................ 58
Gonorroe.................................................................................................................................................. 60
Chlamydia................................................................................................................................................ 60
Andere SOA’s...........................................................................................................................................60
HIV (NIET)................................................................................................................................................60
1
,Eczeem & kinderdermatologie....................................................................................................................62
Eczeem.................................................................................................................................................... 62
Atopisch eczeem (AD) = constitutioneel eczeem.....................................................................................62
Andere eczemen...................................................................................................................................... 68
Contact allergisch eczeem................................................................................................................. 68
Contact irritatief eczeem.....................................................................................................................68
Seborroïsch eczeem.......................................................................................................................... 68
Nummulair eczeem............................................................................................................................ 69
Variceus / veneus / stase eczeem...................................................................................................... 69
Asteatotisch / craquelé eczeem......................................................................................................... 69
Dishydrosiform (dyshidrotisch) eczeem............................................................................................. 69
Lichen simplex chronicus = neurodermitis......................................................................................... 69
Prurigo nodularis = knobbeleczeem................................................................................................... 69
Handeczeem...................................................................................................................................... 70
Kinderdermatologie.................................................................................................................................. 70
Bacteriële infecties............................................................................................................................. 70
Virale infecties.................................................................................................................................... 71
Parasitaire infecties............................................................................................................................ 71
Congenitale naevus............................................................................................................................71
Vasculaire naevi................................................................................................................................. 71
Luierdermatitis....................................................................................................................................72
Pityriasis alba..................................................................................................................................... 72
Seborrhoea capitis neonatorum......................................................................................................... 73
Acne................................................................................................................................................... 73
Fotodermatosen & fototherapie..................................................................................................................74
Fotodermatosen - diagnose..................................................................................................................... 75
Fotodermatosen - pathologieën............................................................................................................... 77
Primaire idiopathische fotodermatosen.............................................................................................. 77
Chemische- en medicatie-geïnduceerde fotodermatosen..................................................................78
Pellagra.............................................................................................................................................. 79
Voorbestaande huidaandoeningen.....................................................................................................80
Starten met fototherapie...........................................................................................................................80
Zonbescherming.......................................................................................................................................81
Pigmentatiestoornissen.............................................................................................................................. 86
Hypopigmentatie & depigmentatie........................................................................................................... 86
Vitiligo................................................................................................................................................. 86
Albinisme............................................................................................................................................89
Hyperpigmentatie..................................................................................................................................... 89
Epheliden & lentigines........................................................................................................................89
Melasma = zwangerschapsmasker = chloasma................................................................................ 90
Ziekten / syndromen met hyperpigmentatie....................................................................................... 90
Medicatie-geïnduceerde hyperpigmentatie........................................................................................ 90
Haar- en nagelaandoeningen...................................................................................................................... 92
Haaraandoeningen...................................................................................................................................92
Niet-cicatricieel................................................................................................................................... 93
Cicatricieel..........................................................................................................................................96
Nagelaandoeningen................................................................................................................................. 96
Onychomycose...................................................................................................................................97
Psoriasis...........................................................................................................................................101
2
, Lichen planus................................................................................................................................... 101
Nagels bij oudere patiënten..............................................................................................................101
Distale onycholyse........................................................................................................................... 101
Onychomadese................................................................................................................................ 101
Retronychie...................................................................................................................................... 102
Ingroeiende nagels...........................................................................................................................102
Pyogeen granuloma......................................................................................................................... 102
Nagelmelanoom............................................................................................................................... 102
Cutane oncologie....................................................................................................................................... 104
Photoaging............................................................................................................................................. 104
Benigne huidtumoren............................................................................................................................. 104
Epidermale huidtumoren.................................................................................................................. 104
Dermale tumoren..............................................................................................................................106
Premaligne huidletsels........................................................................................................................... 107
Actinische keratose (AK).................................................................................................................. 107
Kerato-acanthoom............................................................................................................................108
Maligne huidtumoren (uitz. melanoom).................................................................................................. 108
Epidermale tumoren......................................................................................................................... 108
Naevi...................................................................................................................................................... 110
Maligne melanoom (MM)........................................................................................................................ 111
Huidletsels die soms verward worden met naevi / MM.......................................................................... 113
Andere huidtumoren............................................................................................................................... 113
Dermatofibrosarcoma protuberans (DFSP)...................................................................................... 113
Merkcel carcinoom (MCC)................................................................................................................ 114
Atypisch fibroxanthoma (AFX).......................................................................................................... 114
Xeroderma pigmentosum (XP)......................................................................................................... 114
Behandelingen (incl. dermatochirurgie)..................................................................................................116
Huidziekten op de donkere huid............................................................................................................... 118
Reactieve dermatosen, medicamenteuze erupties & zwangerschapsdermatosen............................. 124
Reactieve dermatosen........................................................................................................................... 124
Vasculitis.......................................................................................................................................... 124
Erythema exsudativum multiforme (EEM)........................................................................................126
Erythema nodosum (EN)..................................................................................................................127
Neutrofiele dermatosen.................................................................................................................... 128
Medicamenteuze erupties...................................................................................................................... 131
Milde medicamenteuze erupties.......................................................................................................131
Ernstige medicamenteuze erupties.................................................................................................. 133
Zwangerschapsdermatosen (NIET)....................................................................................................... 136
Vasculitis.....................................................................................................................................................137
Vasculitis................................................................................................................................................ 137
Conclusie................................................................................................................................................141
Pruritus, urticaria & angio-oedeem.......................................................................................................... 142
Pruritus (jeuk)......................................................................................................................................... 142
Urticaria & angio-oedeem.......................................................................................................................147
Blaarziekten................................................................................................................................................ 151
Auto-immune blaarziekten......................................................................................................................151
Bulleus pemfigoïd.............................................................................................................................151
Pemfigus (zie casussen, dia 19-22)................................................................................................. 153
Dermatitis herpetiformis................................................................................................................... 154
3
, Systeemziekten - cutane lupus.................................................................................................................157
Types cutane lupus................................................................................................................................ 157
Systemische lupus erythematosus...................................................................................................157
Discoïde cutane lupus erythematosus............................................................................................. 157
Subacute cutane lupus erythematosus............................................................................................ 157
Acute cutane lupus erythematosus.................................................................................................. 157
Non-specifieke huidafwijkingen bij SLE............................................................................................158
Behandeling cutane LE.......................................................................................................................... 158
Systeemziekten - dermatomyositis.......................................................................................................... 159
Systeemziekten - sclerodermie.................................................................................................................162
Systeemsclerose.................................................................................................................................... 162
Lokale sclerodermie............................................................................................................................... 163
Exogene dermatosen - contacteczeem & psychogene huidziekten..................................................... 164
Contacteczeem...................................................................................................................................... 164
Contact-irritatief eczeem.................................................................................................................. 164
Contact-allergisch eczeem............................................................................................................... 164
Psychogene huidziekten........................................................................................................................ 166
Dermatitis artefacta.......................................................................................................................... 167
Parasietenwaan................................................................................................................................167
Parapsoriasis & huidlymfomen................................................................................................................ 168
Parapsoriasis..........................................................................................................................................168
Huidlymfomen........................................................................................................................................ 168
Mycosis fungoides (Sézary)............................................................................................................. 170
Cutane CD30+ lymfoproliferatieve aandoeningen........................................................................... 171
Cutane B-cellymfomen..................................................................................................................... 172
Paraneoplastische huidaandoeningen.................................................................................................... 174
Paraneoplastische huidaandoeningen................................................................................................... 174
Wondheling & wondzorg........................................................................................................................... 175
Littekens................................................................................................................................................. 175
Lokale behandeling van ulcera.............................................................................................................. 175
Hypergranulerend ulcus......................................................................................................................... 179
Vertraagde wondheling.......................................................................................................................... 179
Atone wonde.......................................................................................................................................... 179
EXAMEN
● 40 MCQ: 4 mogelijke antwoorden, 1 juist antwoord
● geen giscorrectie, geen verhoogde cesuur
● onderdelen
○ belangrijk: huidinfecties, ernstige drugerupties
○ cutane oncologie: melanoom (SCC, BCC), Morbus Bowen, actinische keratose
○ parapsoriasis / cutaan lymfoom + wondzorg → hooguit 1 vraag
foto’s
● www.huidziekten.nl
● www.dermnetnz.org
4
