HESI RN PHARMACOLOGY REVIEW 2026 V2 –65 QUESTIONS
AND ANSWERS LATEST VERSION WITH GREAT RATIONALES
COMPLETE 100% GRADED A+
PLEASE NOTE: Health care system is continuously changing, guidelines and
recommendation could differ from time to time, the answers of below questions were
made up to our best knowledge and elimination of wrong answers– and remember that
most of the time there are more than a correct answer but you have to choose
theMOSTimportantorpriorityorwhat’swithinnursingscopeof practice.Wetriedourbestto
have all answers correct but we do not guarantee that 100%. You must study andreview
them as well. Good luck!
1. Beforeadministeringalaxativetoabedfastclient,itismostimportantfor the
nurse to perform what assessment?
A. Observetheskinintegrityoftheclient'srectalandsacralareas
B. assesstheclientstrengthinmovingandturninginthe bed
C. evaluatetheclient'sabilitytorecognizetheurgetodefecate
D. determinethefrequencyandconsistencyofbowelmovements
2. A female client with multiple sclerosis reports having less fatigue and
improved memory since she began using the herbal supplement, ginkgo
biloba.Whichinformationismostimportantforthenursetoincludeinthe
teaching plans for this client?
A. Aspirinandnonsteroidalanti-inflammatorydrugsinteractwith
ginkgo
B. nauseaanddiarrheacanoccurwhenusingthissupplement
C. anxietyandheadachesincreasedwithuseofginkgo
D. ginkgobilobauseshouldbelimitedandnottakenduringpregnancy
,HESI RN PHARMACOLOGY REVIEW 2026 V2 –65 QUESTIONS
AND ANSWERS LATEST VERSION WITH GREAT RATIONALES
COMPLETE 100% GRADED A+
3. Inexplainingthebenefitsofthecombinationanti-infectivedrugcodeTMP- SMZ
(Bactrim) to a client receiving the medication for a urinary tract infection,
more rationale to the nurse provide?
A. Eachdrugcouldcausedamagetothekidneysiftakenseparately
B. Onedrugreducestheriskofsideeffectscausedbythedrug
C. whileonedrugproviderelief,theotherfightstheinfection
D. thetwodrugsworktogethertoreduceresistanceofthebacterialinfec
tion of symptoms
4. Client being treated with Haldol for schizophrenia is complaining of jaw
tightnessandastiffneck.Whichinterventionsshouldthenurseimplement?
A. givePRNdoseofdiphenhydramineBenadryl
B. assessclientothersensoryhallucinations
C. massageneckuntilmusclesbegintorelax
D. obtaina12leadEKG
5. Whichinterventionismostimportantforthenurseimplementforaclient is
receiving Lispro Humalog insulin?
A. Checkbloodglucoselevelseverysixhours
B. Providemealsatthesametimethatinsulinisgiven
C. Assessforhypoglycemiabetweenmeals
D. Keepingoralliquidorglucosesourceavailable
6. Clienttakesnonsteroidalanti-inflammatorydrugseverydayforrheumatoid
arthritis is being treated for anemia which intervention is most important
for the nurse to include any plan of care
A. Observeforgastrointestinalbleeding
B. Monitorliverfunctiontestresults
C. Protectskinfrombruising
D. Offereddietaryselectionsrichiniron
,HESI RN PHARMACOLOGY REVIEW 2026 V2 –65 QUESTIONS
AND ANSWERS LATEST VERSION WITH GREAT RATIONALES
COMPLETE 100% GRADED A+
7. A client receives a prescription for theophylline (Theo-Dur) PO to beinitiated
in the morning after the dose of theophylline IV is complete. The
nursedeterminesthat atheophyllineleveldrawnyesterdaywas22mcg/mL.
Based on this information, which action should the nurse implement?
A. Holdthetheophyllinedoseandnotifythehealthcareprovider.
B. Starttheclientonahalf-doseoftheophyllinePO.
C. Thetheophyllinedosecanbeinitiatedasplanned.
D. TheclientisnotreadytobeweanedfromtheIVtothePO route
8. Thenurse is reviewinga client's laboratory results beforea procedurein
whichaneuromuscularblockingagentisastandingorder.Whichfinding
should the nurse report to the health care provider?
A. Hypokalemia
B. Hyponatremia
C. Hypercalcemia
D. Hypomagnesemia
9. The nurse is preparing a child for transport to the operating room for an
emergencyappendectomy.Theanesthesiologistprescribesatropinesulfate
(Atropine), IM STAT. What is the primary purpose for administering this
drug to the child at this time?
A. Decreasetheoralsecretions
B. Reducethechild'sanxiety
C. Potentiatetheopioideffects
D. Preventpossibleperitonitis
10. When caring for a client on digoxin (Lanoxin) therapy, the nurse knows to
bealertfordigoxin(Lanoxin)toxicity.Whichfindingwouldpredisposethis
client to developing digoxin toxicity?
A. Lowserumsodiumlevel
B. Highserumsodiumlevel
C. Lowserumpotassium level
D. Highserumpotassium level
, HESI RN PHARMACOLOGY REVIEW 2026 V2 –65 QUESTIONS
AND ANSWERS LATEST VERSION WITH GREAT RATIONALES
COMPLETE 100% GRADED A+
11. Aclientis receiving anti-infectivedrug therapy fora postoperativeinfection.
Which complaint should alert the nurse to the possibility that the client has
contracted a superinfection?
A. "Mymouthfeelssore"
B. "Ihaveaheadache."
C. "Myearsfeelpluggedup."
D. "Ifeel constipated"
12. Duringtheinitialnursingassessmenthistory,aclienttellsthenursethathe is
taking tetracycline hydrochloride (Sumycin) for urethritis. Which
medication taken concurrently with Sumycin could interfere with its
absorption?
A. Sucralfate(Carafate)
B. Hydrochlorothiazide(Diuril)
C. Acetaminophen(Tylenol)
D. Phenytoin(Dilantin)
13. Followingtheadministrationofsublingualnitroglycerin,whichassessment
finding indicates that the medication was effective?
A. Decreaseinlevelofchestpain
B. Clearbilateralbreathsounds
C. Increaseinbloodpressure
D. Increaseinurinaryoutput
14. Alterationofwhichlaboratoryfindingrepresentstheachievementofa
therapeutic goal for heparin administration?
A. Prothrombintime(PT)
B. Fibrinsplitproducts
C. Plateletcount
D. Partialthromboplastintime(PTT)
AND ANSWERS LATEST VERSION WITH GREAT RATIONALES
COMPLETE 100% GRADED A+
PLEASE NOTE: Health care system is continuously changing, guidelines and
recommendation could differ from time to time, the answers of below questions were
made up to our best knowledge and elimination of wrong answers– and remember that
most of the time there are more than a correct answer but you have to choose
theMOSTimportantorpriorityorwhat’swithinnursingscopeof practice.Wetriedourbestto
have all answers correct but we do not guarantee that 100%. You must study andreview
them as well. Good luck!
1. Beforeadministeringalaxativetoabedfastclient,itismostimportantfor the
nurse to perform what assessment?
A. Observetheskinintegrityoftheclient'srectalandsacralareas
B. assesstheclientstrengthinmovingandturninginthe bed
C. evaluatetheclient'sabilitytorecognizetheurgetodefecate
D. determinethefrequencyandconsistencyofbowelmovements
2. A female client with multiple sclerosis reports having less fatigue and
improved memory since she began using the herbal supplement, ginkgo
biloba.Whichinformationismostimportantforthenursetoincludeinthe
teaching plans for this client?
A. Aspirinandnonsteroidalanti-inflammatorydrugsinteractwith
ginkgo
B. nauseaanddiarrheacanoccurwhenusingthissupplement
C. anxietyandheadachesincreasedwithuseofginkgo
D. ginkgobilobauseshouldbelimitedandnottakenduringpregnancy
,HESI RN PHARMACOLOGY REVIEW 2026 V2 –65 QUESTIONS
AND ANSWERS LATEST VERSION WITH GREAT RATIONALES
COMPLETE 100% GRADED A+
3. Inexplainingthebenefitsofthecombinationanti-infectivedrugcodeTMP- SMZ
(Bactrim) to a client receiving the medication for a urinary tract infection,
more rationale to the nurse provide?
A. Eachdrugcouldcausedamagetothekidneysiftakenseparately
B. Onedrugreducestheriskofsideeffectscausedbythedrug
C. whileonedrugproviderelief,theotherfightstheinfection
D. thetwodrugsworktogethertoreduceresistanceofthebacterialinfec
tion of symptoms
4. Client being treated with Haldol for schizophrenia is complaining of jaw
tightnessandastiffneck.Whichinterventionsshouldthenurseimplement?
A. givePRNdoseofdiphenhydramineBenadryl
B. assessclientothersensoryhallucinations
C. massageneckuntilmusclesbegintorelax
D. obtaina12leadEKG
5. Whichinterventionismostimportantforthenurseimplementforaclient is
receiving Lispro Humalog insulin?
A. Checkbloodglucoselevelseverysixhours
B. Providemealsatthesametimethatinsulinisgiven
C. Assessforhypoglycemiabetweenmeals
D. Keepingoralliquidorglucosesourceavailable
6. Clienttakesnonsteroidalanti-inflammatorydrugseverydayforrheumatoid
arthritis is being treated for anemia which intervention is most important
for the nurse to include any plan of care
A. Observeforgastrointestinalbleeding
B. Monitorliverfunctiontestresults
C. Protectskinfrombruising
D. Offereddietaryselectionsrichiniron
,HESI RN PHARMACOLOGY REVIEW 2026 V2 –65 QUESTIONS
AND ANSWERS LATEST VERSION WITH GREAT RATIONALES
COMPLETE 100% GRADED A+
7. A client receives a prescription for theophylline (Theo-Dur) PO to beinitiated
in the morning after the dose of theophylline IV is complete. The
nursedeterminesthat atheophyllineleveldrawnyesterdaywas22mcg/mL.
Based on this information, which action should the nurse implement?
A. Holdthetheophyllinedoseandnotifythehealthcareprovider.
B. Starttheclientonahalf-doseoftheophyllinePO.
C. Thetheophyllinedosecanbeinitiatedasplanned.
D. TheclientisnotreadytobeweanedfromtheIVtothePO route
8. Thenurse is reviewinga client's laboratory results beforea procedurein
whichaneuromuscularblockingagentisastandingorder.Whichfinding
should the nurse report to the health care provider?
A. Hypokalemia
B. Hyponatremia
C. Hypercalcemia
D. Hypomagnesemia
9. The nurse is preparing a child for transport to the operating room for an
emergencyappendectomy.Theanesthesiologistprescribesatropinesulfate
(Atropine), IM STAT. What is the primary purpose for administering this
drug to the child at this time?
A. Decreasetheoralsecretions
B. Reducethechild'sanxiety
C. Potentiatetheopioideffects
D. Preventpossibleperitonitis
10. When caring for a client on digoxin (Lanoxin) therapy, the nurse knows to
bealertfordigoxin(Lanoxin)toxicity.Whichfindingwouldpredisposethis
client to developing digoxin toxicity?
A. Lowserumsodiumlevel
B. Highserumsodiumlevel
C. Lowserumpotassium level
D. Highserumpotassium level
, HESI RN PHARMACOLOGY REVIEW 2026 V2 –65 QUESTIONS
AND ANSWERS LATEST VERSION WITH GREAT RATIONALES
COMPLETE 100% GRADED A+
11. Aclientis receiving anti-infectivedrug therapy fora postoperativeinfection.
Which complaint should alert the nurse to the possibility that the client has
contracted a superinfection?
A. "Mymouthfeelssore"
B. "Ihaveaheadache."
C. "Myearsfeelpluggedup."
D. "Ifeel constipated"
12. Duringtheinitialnursingassessmenthistory,aclienttellsthenursethathe is
taking tetracycline hydrochloride (Sumycin) for urethritis. Which
medication taken concurrently with Sumycin could interfere with its
absorption?
A. Sucralfate(Carafate)
B. Hydrochlorothiazide(Diuril)
C. Acetaminophen(Tylenol)
D. Phenytoin(Dilantin)
13. Followingtheadministrationofsublingualnitroglycerin,whichassessment
finding indicates that the medication was effective?
A. Decreaseinlevelofchestpain
B. Clearbilateralbreathsounds
C. Increaseinbloodpressure
D. Increaseinurinaryoutput
14. Alterationofwhichlaboratoryfindingrepresentstheachievementofa
therapeutic goal for heparin administration?
A. Prothrombintime(PT)
B. Fibrinsplitproducts
C. Plateletcount
D. Partialthromboplastintime(PTT)
